Search Results - "Wick, Jo A"
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Using Bayesian hierarchical modeling for performance evaluation of clinical trial accrual for a cancer center
Published in Contemporary clinical trials communications (01-04-2024)“…Slow patient accrual in cancer clinical trials is always a concern. In 2021, the University of Kansas Comprehensive Cancer Center (KUCC), an NCI-designated…”
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2
Women Physicians and Promotion in Academic Medicine
Published in The New England journal of medicine (26-11-2020)“…In analyses of data on graduates from all U.S. medical schools from 1979 through 2013, women were less likely than men to be promoted from assistant to…”
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Programming of infant neurodevelopment by maternal obesity: potential role of maternal inflammation and insulin resistance
Published in Asia Pacific Journal of Clinical Nutrition (01-06-2017)“…Background and Objectives: Recent studies show that maternal obesity is associated with impaired offspring neurodevelopmental outcomes. The mechanism…”
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4
Improving the efficiency of clinical trials by standardizing processes for Investigator Initiated Trials
Published in Contemporary clinical trials communications (01-06-2020)“…Early phase clinical trials are the first step in testing new medications and therapeutics developed by clinical and biomedical investigators. These trials aim…”
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5
Potential factors associated with perceived cognitive impairment in breast cancer survivors
Published in Supportive care in cancer (01-11-2015)“…Purpose This cross-sectional study was designed to explore potential factors associated with perceived cognitive impairment (PCI) in breast cancer survivors…”
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Assessing the incidence and severity of drug adverse events: a Bayesian hierarchical cumulative logit model
Published in Journal of biopharmaceutical statistics (03-03-2024)“…Detection of safety signals based on multiple comparisons of adverse events (AEs) between two treatments in a clinical trial involves evaluations requiring…”
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7
Supplemental Screening With Automated Breast Ultrasound in Women With Dense Breasts: Comparing Notification Methods and Screening Behaviors
Published in American journal of roentgenology (1976) (01-01-2018)“…Supplemental screening with ultrasound has been shown to detect additional breast malignancies in women with dense breast tissue and normal mammogram findings…”
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Improved mortality analysis in early‐phase dose‐ranging clinical trials for emergency medical diseases using Bayesian time‐to‐event models with active comparators
Published in Statistics in medicine (30-08-2024)“…Emergency medical diseases (EMDs) are the leading cause of death worldwide. A time‐to‐death analysis is needed to accurately identify the risks and describe…”
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A Connection Between Baseball and Clinical Trials Found in "Slugging Percentage is Not a Percentage-And Why That Matters"
Published in The American statistician (02-01-2022)Get full text
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10
DHA supplementation for early preterm birth prevention: An application of Bayesian finite mixture models to adaptive clinical trial design optimization
Published in Contemporary clinical trials (01-09-2024)“…Early preterm birth (ePTB) - born before 34 weeks of gestation - poses a significant public health challenge. Two randomized trials indicated an ePTB reduction…”
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Designing and analyzing clinical trials for personalized medicine via Bayesian models
Published in Pharmaceutical statistics : the journal of the pharmaceutical industry (01-05-2021)“…Patients with different characteristics (e.g., biomarkers, risk factors) may have different responses to the same medicine. Personalized medicine clinical…”
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T-cell trafficking plays an essential role in tumor immunity
Published in Laboratory investigation (01-01-2019)“…Distinct populations of effector memory T cells use different homing receptors to traffic to the skin and gut. Whether tissue-selective T cells are needed for…”
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Formula with long-chain polyunsaturated fatty acids reduces incidence of allergy in early childhood
Published in Pediatric allergy and immunology (01-03-2016)“…Background Allergy has sharply increased in affluent Western countries in the last 30 years. N‐3 long‐chain polyunsaturated fatty acids (n‐3 LCPUFAs) may…”
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Race, Gender, and Faculty Retention in Academic Medicine
Published in JAMA network open (04-11-2024)“…Importance Poor retention may be associated with lack of faculty diversity in academic medicine. Objective To examine differences in faculty retention by…”
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15
A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax®) in patients with peritoneal malignancies
Published in Cancer chemotherapy and pharmacology (01-05-2015)“…Purpose This multicenter, open-label, dose-escalating, phase I study evaluated the safety, tolerability, pharmacokinetics and preliminary tumor response of a…”
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Using a Bayesian model of the joint distribution of pain and time on medication to decide on pain medication for neuropathy
Published in Communication in statistics. Case studies and data analysis (2023)“…The PAIN-CONTRoLS trial compared four medications in treating Cryptogenic sensory polyneuropathy. The primary outcome was a utility function that combined two…”
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Accrual Prediction Program: A web-based clinical trials tool for monitoring and predicting accrual for early-phase cancer studies
Published in Clinical trials (London, England) (01-12-2019)“…Background Monitoring subject recruitment is key to the success of a clinical trial. Accordingly, researchers have developed accrual-monitoring tools to…”
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Multidisciplinary group clinic appointments: the Self-Management and Care of Heart Failure (SMAC-HF) trial
Published in Circulation. Heart failure (01-11-2014)“…This trial tested the effects of multidisciplinary group clinic appointments on the primary outcome of time to first heart failure (HF) rehospitalization or…”
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Bayesian design for two-arm randomized Phase II clinical trials with endpoints from the exponential family using multiple constraints
Published in Journal of biopharmaceutical statistics (03-09-2018)“…Frequentist design for two-arm randomized Phase II clinical trials with outcomes from the exponential dispersion family was proposed previously, where the…”
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20
A Bayesian Analysis of Synchronous Distance Learning versus Matched Traditional Control in Graduate Biostatistics Courses
Published in The American statistician (01-05-2017)“…Distance learning can be useful for bridging geographical barriers to education in rural settings. However, empirical evidence on the equivalence of distance…”
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