Search Results - "Wicht, J"

Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria by Wicht, Kathryn J, Mok, Sachel, Fidock, David A

“…Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium…”
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Effects of compressibility on driving zonal flow in gas giants by Gastine, T., Wicht, J.

“…► We model compressible convection to explore the properties of zonal winds in rapidly rotating spherical shells. ► We perform a systematic parametric study…”
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From solar-like to antisolar differential rotation in cool stars by Gastine, T., Yadav, R. K., Morin, J., Reiners, A., Wicht, J.

“…Stellar differential rotation can be separated into two main regimes: solar-like when the equator rotates faster than the poles and antisolar when the polar…”
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Zonal flow scaling in rapidly-rotating compressible convection by Gastine, T., Heimpel, M., Wicht, J.

“…•We derive the compressible beta-effect in rotating anelastic spherical shells.•We apply the compressible Rhines scale to the gas giant planets Jupiter and…”
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Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine by Ross, Leila S., Dhingra, Satish K., Mok, Sachel, Yeo, Tomas, Wicht, Kathryn J., Kümpornsin, Krittikorn, Takala-Harrison, Shannon, Witkowski, Benoit, Fairhurst, Rick M., Ariey, Frederic, Menard, Didier, Fidock, David A.

“…The widely used antimalarial combination therapy dihydroartemisinin + piperaquine (DHA + PPQ) has failed in Cambodia. Here, we perform a genomic analysis that…”
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Zonal winds in the gas planets driven by convection above a stably stratified layer by Wulff, Paula N, Dietrich, W, Christensen, U R, Wicht, J

“…ABSTRACT The analysis of the recent gravity measurements of Jupiter and Saturn reveal that the zonal winds observed on their surfaces reach several thousand…”
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Ocean-driven heating of Europa’s icy shell at low latitudes by Soderlund, K. M., Schmidt, B. E., Wicht, J., Blankenship, D. D.

“…On Jupiter’s icy moon Europa, enigmatic chaos terrain—where the icy crust is cut by a jumble of ridges and cracks—occurs most commonly at lower latitudes…”
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Zonal flow regimes in rotating anelastic spherical shells: An application to giant planets by Gastine, T., Wicht, J., Aurnou, J.M.

“…•We study different zonal flow regimes in rotating anelastic spherical shells.•We carry out a systematic parametric study for various density stratifications…”
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International Geomagnetic Reference Field: the thirteenth generation by Alken, P., Thébault, E., Beggan, C. D., Amit, H., Aubert, J., Baerenzung, J., Bondar, T. N., Brown, W. J., Califf, S., Chambodut, A., Chulliat, A., Cox, G. A., Finlay, C. C., Fournier, A., Gillet, N., Grayver, A., Hammer, M. D., Holschneider, M., Huder, L., Hulot, G., Jager, T., Kloss, C., Korte, M., Kuang, W., Kuvshinov, A., Langlais, B., Léger, J.-M., Lesur, V., Livermore, P. W., Lowes, F. J., Macmillan, S., Magnes, W., Mandea, M., Marsal, S., Matzka, J., Metman, M. C., Minami, T., Morschhauser, A., Mound, J. E., Nair, M., Nakano, S., Olsen, N., Pavón-Carrasco, F. J., Petrov, V. G., Ropp, G., Rother, M., Sabaka, T. J., Sanchez, S., Saturnino, D., Schnepf, N. R., Shen, X., Stolle, C., Tangborn, A., Tøffner-Clausen, L., Toh, H., Torta, J. M., Varner, J., Vervelidou, F., Vigneron, P., Wardinski, I., Wicht, J., Woods, A., Yang, Y., Zeren, Z., Zhou, B.

“…In December 2019, the International Association of Geomagnetism and Aeronomy (IAGA) Division V Working Group (V-MOD) adopted the thirteenth generation of the…”
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Sequential assimilation of geomagnetic observations: perspectives for the reconstruction and prediction of core dynamics by Sanchez, S, Wicht, J, Bärenzung, J, Holschneider, M

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The BepiColombo Planetary Magnetometer MPO-MAG: What Can We Learn from the Hermean Magnetic Field? by Heyner, D., Auster, H.-U., Fornaçon, K.-H., Carr, C., Richter, I., Mieth, J. Z. D., Kolhey, P., Exner, W., Motschmann, U., Baumjohann, W., Matsuoka, A., Magnes, W., Berghofer, G., Fischer, D., Plaschke, F., Nakamura, R., Narita, Y., Delva, M., Volwerk, M., Balogh, A., Dougherty, M., Horbury, T., Langlais, B., Mandea, M., Masters, A., Oliveira, J. S., Sánchez-Cano, B., Slavin, J. A., Vennerstrøm, S., Vogt, J., Wicht, J., Glassmeier, K.-H.

“…The magnetometer instrument MPO-MAG on-board the Mercury Planetary Orbiter (MPO) of the BepiColombo mission en-route to Mercury is introduced, with its…”
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Contributions of Jupiter's Deep‐Reaching Surface Winds to Magnetic Field Structure and Secular Variation by Wicht, J., Christensen, U. R.

“…NASA's Juno mission delivered gravity data of exceptional quality. They indicate that the zonal winds, which rule the dynamics of Jupiter's cloud deck, must…”
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Theory and Modeling of Planetary Dynamos by Wicht, J., Tilgner, A.

“…Numerical dynamo models are increasingly successful in modeling many features of the geomagnetic field. Moreover, they have proven to be a useful tool for…”
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Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches by Amod, Leah, Mohunlal, Roxanne, Teixeira, Nicole, Egan, Timothy J., Wicht, Kathryn J.

“…The biomineral haemozoin, or its synthetic analogue β-haematin (βH), has been the focus of several target-based screens for activity against Plasmodium…”
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Explaining Jupiter's magnetic field and equatorial jet dynamics by Gastine, T., Wicht, J., Duarte, L. D. V., Heimpel, M., Becker, A.

“…Spacecraft data reveal a very Earth‐like Jovian magnetic field. This is surprising since numerical simulations have shown that the vastly different interiors…”
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On the generation and segregation of helicity in geodynamo simulations by Ranjan, A, Davidson, P A, Christensen, U R, Wicht, J

“…SUMMARY Helicity, the inner product of velocity and vorticity, is considered an important ingredient for the maintenance of a dipolar magnetic field in the…”
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Internally driven inertial waves in geodynamo simulations by Ranjan, A, Davidson, P A, Christensen, U R, Wicht, J

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Curcumin Inhibits Constitutive STAT3 Phosphorylation in Human Pancreatic Cancer Cell lines and Downregulation of Survivin/BIRC5 Gene Expression by Glienke, W., Maute, L., Wicht, J., Bergmann, L.

“…ABSTRACT The purpose of this study was to determine the effect of curcumin on Survivin/BIRC5 and on the role of signal transducer and activator of…”
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Anelastic convection-driven dynamo benchmarks by Jones, C.A., Boronski, P., Brun, A.S., Glatzmaier, G.A., Gastine, T., Miesch, M.S., Wicht, J.

“…► Anelastic dynamo benchmark solutions have been proposed. ► Valid for convection driven compressible dynamos in spherical geometry. ► Four different codes…”
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Self-determined use of provided powered oral hygiene devices leads to improved gingival health after 1 year: a longitudinal clinical trial by Deeg, I, Wicht, M J, Barbe, A G, Derman, S H M

“…Our study aimed to evaluate the long-term concordance and acceptance when using powered devices for everyday oral hygiene routine and gingival health in…”
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