Search Results - "Wichmann, H. Erich"

Differences between human plasma and serum metabolite profiles by Yu, Zhonghao, Kastenmüller, Gabi, He, Ying, Belcredi, Petra, Möller, Gabriele, Prehn, Cornelia, Mendes, Joaquim, Wahl, Simone, Roemisch-Margl, Werner, Ceglarek, Uta, Polonikov, Alexey, Dahmen, Norbert, Prokisch, Holger, Xie, Lu, Li, Yixue, Wichmann, H-Erich, Peters, Annette, Kronenberg, Florian, Suhre, Karsten, Adamski, Jerzy, Illig, Thomas, Wang-Sattler, Rui

“…Human plasma and serum are widely used matrices in clinical and biological studies. However, different collecting procedures and the coagulation cascade…”
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Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting by Suhre, Karsten, Meisinger, Christa, Döring, Angela, Altmaier, Elisabeth, Belcredi, Petra, Gieger, Christian, Chang, David, Milburn, Michael V, Gall, Walter E, Weinberger, Klaus M, Mewes, Hans-Werner, Hrabé de Angelis, Martin, Wichmann, H-Erich, Kronenberg, Florian, Adamski, Jerzy, Illig, Thomas

“…Metabolomics is the rapidly evolving field of the comprehensive measurement of ideally all endogenous metabolites in a biological fluid. However, no single…”
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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum by Gieger, Christian, Geistlinger, Ludwig, Altmaier, Elisabeth, Hrabé de Angelis, Martin, Kronenberg, Florian, Meitinger, Thomas, Mewes, Hans-Werner, Wichmann, H-Erich, Weinberger, Klaus M, Adamski, Jerzy, Illig, Thomas, Suhre, Karsten

“…The rapidly evolving field of metabolomics aims at a comprehensive measurement of ideally all endogenous metabolites in a cell or body fluid. It thereby…”
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Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants by Hinney, Anke, Nguyen, Thuy Trang, Scherag, André, Friedel, Susann, Brönner, Günter, Müller, Timo Dirk, Grallert, Harald, Illig, Thomas, Wichmann, H-Erich, Rief, Winfried, Schäfer, Helmut, Hebebrand, Johannes

“…Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predisposing to obesity are not very well understood. We have…”
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Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture by Stuart, Philip E., Nair, Rajan P., Tsoi, Lam C., Tejasvi, Trilokraj, Das, Sayantan, Kang, Hyun Min, Ellinghaus, Eva, Chandran, Vinod, Callis-Duffin, Kristina, Ike, Robert, Li, Yanming, Wen, Xiaoquan, Enerbäck, Charlotta, Gudjonsson, Johann E., Kõks, Sulev, Kingo, Külli, Esko, Tõnu, Mrowietz, Ulrich, Reis, Andre, Wichmann, H. Erich, Gieger, Christian, Hoffmann, Per, Nöthen, Markus M., Winkelmann, Juliane, Kunz, Manfred, Moreta, Elvia G., Mease, Philip J., Ritchlin, Christopher T., Bowcock, Anne M., Krueger, Gerald G., Lim, Henry W., Weidinger, Stephan, Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Gladman, Dafna D., Abecasis, Gonçalo R., Elder, James T.

“…Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up to 30% of people with PsV eventually develop psoriatic arthritis…”
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Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci by Ellinghaus, David, Ellinghaus, Eva, Nair, Rajan P., Stuart, Philip E., Esko, Tõnu, Metspalu, Andres, Debrus, Sophie, Raelson, John V., Tejasvi, Trilokraj, Belouchi, Majid, West, Sarah L., Barker, Jonathan N., Kõks, Sulev, Kingo, Külli, Balschun, Tobias, Palmieri, Orazio, Annese, Vito, Gieger, Christian, Wichmann, H. Erich, Kabesch, Michael, Trembath, Richard C., Mathew, Christopher G., Abecasis, Gonçalo R., Weidinger, Stephan, Nikolaus, Susanna, Schreiber, Stefan, Elder, James T., Weichenthal, Michael, Nothnagel, Michael, Franke, Andre

“…Psoriasis (PS) and Crohn disease (CD) have been shown to be epidemiologically, pathologically, and therapeutically connected, but little is known about their…”
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Metabolomic Fingerprints in Large Population Cohorts: Impact of Preanalytical Heterogeneity by Ghini, Veronica, Abuja, Peter M, Polasek, Ozren, Kozera, Lukasz, Laiho, Päivi, Anton, Gabriele, Zins, Marie, Klovins, Janis, Metspalu, Andres, Wichmann, H -Erich, Gieger, Christian, Luchinat, Claudio, Zatloukal, Kurt, Turano, Paola

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Association of early repolarization pattern on ECG with risk of cardiac and all-cause mortality: a population-based prospective cohort study (MONICA/KORA) by Sinner, Moritz F, Reinhard, Wibke, Müller, Martina, Beckmann, Britt-Maria, Martens, Eimo, Perz, Siegfried, Pfeufer, Arne, Winogradow, Janina, Stark, Klaus, Meisinger, Christa, Wichmann, H-Erich, Peters, Annette, Riegger, Günter A J, Steinbeck, Gerhard, Hengstenberg, Christian, Kääb, Stefan

“…Early repolarization pattern (ERP) on electrocardiogram was associated with idiopathic ventricular fibrillation and sudden cardiac arrest in a case-control…”
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Allergies in high-risk schoolchildren after early intervention with cow's milk protein hydrolysates: 10-year results from the German Infant Nutritional Intervention (GINI) study by von Berg, Andrea, MD, Filipiak-Pittroff, Birgit, MSc, Krämer, Ursula, PhD, Hoffmann, Barbara, MD, Link, Elke, Beckmann, Christina, MD, Hoffmann, Ute, MD, Reinhardt, Dietrich, MD, Grübl, Armin, MD, Heinrich, Joachim, PhD, Wichmann, H.-Erich, MD, PhD, Bauer, Carl-P., MD, Koletzko, Sibylle, MD, Berdel, Dietrich, MD

“…Background The long-term effect of nutritional intervention with hydrolysate infant formulas on allergic manifestations in high-risk children is uncertain…”
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A genome-wide perspective of genetic variation in human metabolism by Suhre, Karsten, Illig, Thomas, Gieger, Christian, Zhai, Guangju, Römisch-Margl, Werner, Wang-Sattler, Rui, Prehn, Cornelia, Altmaier, Elisabeth, Kastenmüller, Gabi, Kato, Bernet S, Mewes, Hans-Werner, Meitinger, Thomas, de Angelis, Martin Hrabé, Kronenberg, Florian, Soranzo, Nicole, Wichmann, H-Erich, Spector, Tim D, Adamski, Jerzy

“…Serum metabolite concentrations provide a direct readout of biological processes in the human body, and they are associated with disorders such as…”
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The association between fine particulate air pollution and hospital emergency room visits for cardiovascular diseases in Beijing, China by Guo, Yuming, Jia, Yuping, Pan, Xiaochuan, Liu, Liqun, Wichmann, H.-Erich

“…Because epidemiological studies have yielded different results, the association between exposure to fine particulate matter less than 2.5 μm in aerodynamic…”
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Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study by Cuellar-Partida, Gabriel, Lu, Yi, Kho, Pik Fang, Hewitt, Alex W., Wichmann, H.-Erich, Yazar, Seyhan, Stambolian, Dwight, Bailey-Wilson, Joan E., Wojciechowski, Robert, Wang, Jie Jin, Mitchell, Paul, Mackey, David A., MacGregor, Stuart

“…ABSTRACT Myopia is the largest cause of uncorrected visual impairments globally and its recent dramatic increase in the population has made it a major public…”
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Atopic Diseases, Allergic Sensitization, and Exposure to Traffic-related Air Pollution in Children by Morgenstern, Verena, Zutavern, Anne, Cyrys, Josef, Brockow, Inken, Koletzko, Sibylle, Kramer, Ursula, Behrendt, Heidrun, Herbarth, Olf, von Berg, Andrea, Bauer, Carl Peter, Wichmann, H.-Erich, Heinrich, Joachim, GINI Study Group, and LISA Study Group

“…In vitro studies, animal experiments, and human exposure studies have shown how ambient air pollution increases the risk of atopic diseases. However, results…”
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Low emission zones reduce PM10 mass concentrations and diesel soot in German cities by Cyrys, Josef, Peters, Annette, Soentgen, Jens, Wichmann, H.-Erich

“…In many European cities mass concentrations of PM 10 (particles less than 10 μm in size) are still exceeding air quality standards as set by the European…”
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Human metabolic individuality in biomedical and pharmaceutical research by Suhre, Karsten, Shin, So-Youn, Petersen, Ann-Kristin, Mohney, Robert P., Meredith, David, Wägele, Brigitte, Altmaier, Elisabeth, Deloukas, Panos, Erdmann, Jeanette, Grundberg, Elin, Hammond, Christopher J., de Angelis, Martin Hrabé, Kastenmüller, Gabi, Köttgen, Anna, Kronenberg, Florian, Mangino, Massimo, Meisinger, Christa, Meitinger, Thomas, Mewes, Hans-Werner, Milburn, Michael V., Prehn, Cornelia, Raffler, Johannes, Ried, Janina S., Römisch-Margl, Werner, Samani, Nilesh J., Small, Kerrin S., -Erich Wichmann, H., Zhai, Guangju, Illig, Thomas, Spector, Tim D., Adamski, Jerzy, Soranzo, Nicole, Gieger, Christian

“…Genome-wide association studies (GWAS) have identified many risk loci for complex diseases, but effect sizes are typically small and information on the…”
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Source apportionment of ambient particles: Comparison of positive matrix factorization analysis applied to particle size distribution and chemical composition data by Gu, Jianwei, Pitz, Mike, Schnelle-Kreis, Jürgen, Diemer, Jürgen, Reller, Armin, Zimmermann, Ralf, Soentgen, Jens, Stoelzel, Matthias, Wichmann, H.-Erich, Peters, Annette, Cyrys, Josef

“…Positive matrix factorization (PMF) method was used to identify the sources of ambient particles (PM 10) in Augsburg in winter 2006/07. The analyses were…”
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Wnt Signaling and Dupuytren's Disease by Dolmans, Guido H, Werker, Paul M, Hennies, Hans C, Furniss, Dominic, Festen, Eleonora A, Franke, Andre, Franke, Lude, Becker, Kerstin, van der Vlies, Pieter, Wolffenbuttel, Bruce H, Tinschert, Sigrid, Toliat, Mohammad R, Nothnagel, Michael, Klopp, Norman, Wichmann, H.-Erich, Nürnberg, Peter, Giele, Henk, Ophoff, Roel A, Wijmenga, Cisca

“…Little is known about the cause of Dupuytren's disease, in which fibromatosis leads to flexion contractures of the hands and fingers. This genomic study…”
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Air Temperature and the Occurrence of Myocardial Infarction in Augsburg, Germany by WOLF, Kathrin, SCHNEIDER, Alexandra, BREITNER, Susanne, VON KLOT, Stephanie, MEISINGER, Christa, CYRYS, Josef, HYMER, Heiko, WICHMANN, H. -Erich, PETERS, Annette

“…Air temperature changes have been associated with cardiovascular mortality and morbidity. The objective of this study was to examine in detail the…”
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Effects of smoking and smoking cessation on human serum metabolite profile: results from the KORA cohort study by Xu, Tao, Holzapfel, Christina, Dong, Xiao, Bader, Erik, Yu, Zhonghao, Prehn, Cornelia, Perstorfer, Katrin, Jaremek, Marta, Roemisch-Margl, Werner, Rathmann, Wolfgang, Li, Yixue, Wichmann, H Erich, Wallaschofski, Henri, Ladwig, Karl H, Theis, Fabian, Suhre, Karsten, Adamski, Jerzy, Illig, Thomas, Peters, Annette, Wang-Sattler, Rui

“…Metabolomics helps to identify links between environmental exposures and intermediate biomarkers of disturbed pathways. We previously reported variations in…”
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Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls by Timofeeva, Maria N, Hung, Rayjean J, Rafnar, Thorunn, Christiani, David C, Field, John K, Bickeböller, Heike, Risch, Angela, McKay, James D, Wang, Yufei, Dai, Juncheng, Gaborieau, Valerie, McLaughlin, John, Brenner, Darren, Narod, Steven A, Caporaso, Neil E, Albanes, Demetrius, Thun, Michael, Eisen, Timothy, Wichmann, H-Erich, Rosenberger, Albert, Han, Younghun, Chen, Wei, Zhu, Dakai, Spitz, Margaret, Wu, Xifeng, Pande, Mala, Zhao, Yang, Zaridze, David, Szeszenia-Dabrowska, Neonilia, Lissowska, Jolanta, Rudnai, Peter, Fabianova, Eleonora, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Krokan, Hans E, Gabrielsen, Maiken Elvestad, Skorpen, Frank, Vatten, Lars, Njølstad, Inger, Chen, Chu, Goodman, Gary, Lathrop, Mark, Benhamou, Simone, Vooder, Tõnu, Välk, Kristjan, Nelis, Mari, Metspalu, Andres, Raji, Olaide, Chen, Ying, Gosney, John, Liloglou, Triantafillos, Muley, Thomas, Dienemann, Hendrik, Thorleifsson, Gudmar, Shen, Hongbing, Stefansson, Kari, Brennan, Paul, Amos, Christopher I, Houlston, Richard, Landi, Maria Teresa

“…Recent genome-wide association studies (GWASs) have identified common genetic variants at 5p15.33, 6p21-6p22 and 15q25.1 associated with lung cancer risk…”
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