Exploring the association between phase angle of bioimpedance at 50 kHz and cardiovascular risk

Cardiovascular diseases are characterized by chronic inflammation, leading to increased inflammatory markers that can cause cell damage and death. Phase angle has emerged as a marker of cellular health. It is considered a prognostic factor in various acute and chronic conditions. However, few studie...

Full description

Saved in:

Bibliographic Details
Published in:	BMC cardiovascular disorders Vol. 24; no. 1; pp. 606 - 7
Main Authors:	de Borba, Evandro Lucas, Wichbold, Cristina, Ceolin, Jamile, Gonçalves, Marcelo Rodrigues, Cañon-Montañez, Wilson, Padoin, Alexandre Vontobel, Mattiello, Rita
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 29-10-2024 BioMed Central BMC
Subjects:	Adult Age Aged Bioelectrical Impedance Analysis Blood pressure Body Composition Cardiac patients Cardiovascular Disease Cardiovascular diseases Cardiovascular Diseases - diagnosis Cardiovascular Diseases - epidemiology Cardiovascular Diseases - physiopathology Cardiovascular Risk Calculator Cell death Cholesterol Chronic illnesses Cross-Sectional Studies Diabetes Electric Impedance Family income Female Health care industry Heart Disease Risk Factors Heart diseases High density lipoprotein Humans Hypertension Inflammation Lipoproteins Male Medical research Medicine, Experimental Metabolic disorders Metabolic syndrome Middle Aged Mortality Phase Angle Predictive Value of Tests Primary health care Prognosis Regression analysis Risk Assessment Risk factors Risk groups Statistical analysis Statistical models Variables Brazil Portugal Cardiovascular Disease Cardiovascular Risk Calculator Bioelectrical Impedance Analysis Phase Angle
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Cardiovascular diseases are characterized by chronic inflammation, leading to increased inflammatory markers that can cause cell damage and death. Phase angle has emerged as a marker of cellular health. It is considered a prognostic factor in various acute and chronic conditions. However, few studies have examined its association with cardiovascular disease risk measures. This study aims to investigate the relationship between phase angle, the general Framingham risk score, and the HEARTS cardiovascular risk score. This cross-sectional study included a convenience sample of adult patients of 2 primary health care services. Phase angle was measured using multifrequency bioimpedance analysis at 50 kHz. The risk of cardiovascular events was calculated using the Framingham and HEARTS risk scores. Statistical analysis included generalized linear regression models, unadjusted and adjusted according to sex and age, to determine the association between scores, risk factors, and phase angle. The study included 164 individuals with a mean age 52.2 (SD 17.9). According to the HEARTS score, low-risk patients had higher phase angle values than those with high or very high risk [ß = -0.57 (95% CI -0.95; -0.19), P = 0.003]. Framingham scores showed a trend toward significance for higher mean phase angle values in low-risk than high-risk patients [ß = -0.43 (95% CI -0.88 to 0.02), P = 0.06]. Phase angle values were lower in high and very high-risk patients than in low-risk patients, which shows that phase angle is a promising risk predictor for patients with cardiovascular diseases.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-024-04211-4