Search Results - "Wibroe, Peter P"
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An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil®, Caelyx®, DOXOrubicin, and SinaDoxosome
Published in Journal of controlled release (10-01-2016)“…In order to improve patient's benefit and safety, comprehensive regulatory guidelines on specificities of Non-Biological Complex Drugs (NBCDs), such as…”
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Material properties in complement activation
Published in Advanced drug delivery reviews (16-09-2011)“…Uncontrolled complement activation can induce many inflammatory and life threatening conditions. Accordingly, the role of complement in initiation of adverse…”
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Citrem modulates internal nanostructure of glyceryl monooleate dispersions and bypasses complement activation: Towards development of safe tunable intravenous lipid nanocarriers
Published in Nanomedicine (01-11-2015)“…Abstract Lyotropic non-lamellar liquid crystalline (LLC) aqueous nanodispersions hold a great promise in drug solubilization and delivery, but these…”
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A structurally diverse library of safe-by-design citrem-phospholipid lamellar and non-lamellar liquid crystalline nano-assemblies
Published in Journal of controlled release (10-10-2016)“…Non-lamellar liquid crystalline aqueous nanodispersions, known also as ISAsomes (internally self-assembled ‘somes’ or nanoparticles), are gaining increasing…”
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Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective
Published in Nanomedicine (01-09-2012)“…Abstract The oral route for delivery of pharmaceuticals is the most widely used and accepted. Nanoparticles and microparticles are increasingly being applied…”
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Perspectives on carbon nanotube-mediated adverse immune effects
Published in Advanced drug delivery reviews (01-12-2012)“…Carbon nanotubes are entities of different morphology and aspect ratios with anisotropic character. Due to their unique electronic, photonic, mechanical and…”
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Soluble and immobilized graphene oxide activates complement system differently dependent on surface oxidation state
Published in Biomaterials (01-02-2016)“…Abstract Graphene oxide (GO) is believed to become applicable in biomedical products and medicine, thereby necessitating appropriate safety evaluation…”
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Polymeric particulate technologies for oral drug delivery and targeting: A pathophysiological perspective
Published in Maturitas (01-09-2012)“…Abstract The oral route for delivery of pharmaceuticals is the most widely used and accepted. Nanoparticles and microparticles are increasingly being applied…”
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Structural profiling and biological performance of phospholipid–hyaluronan functionalized single-walled carbon nanotubes
Published in Journal of controlled release (10-09-2013)“…In spite of significant insolubility and toxicity, carbon nanotubes (CNTs) erupt into the biomedical research, and create an increasing interest in the field…”
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Genomic perspectives in inter-individual adverse responses following nanomedicine administration: The way forward
Published in Advanced drug delivery reviews (01-10-2012)“…The underlying mechanism of intravenous infusion-related adverse reactions inherent to regulatory-approved nanomedicines still remains elusive. There are…”
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Surfactant-mediated complement activation in beagle dogs
Published in International immunopharmacology (01-09-2013)Get full text
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The Role of Complement in Antibody Therapy for Infectious Diseases
Published in Microbiology spectrum (01-04-2014)“…The complement system is part of the innate immune system, eliciting central immunoregulatory functions. Detection of foreign surfaces is either achieved…”
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Perspectives on carbon nanotube-mediated adverse immune effects: Nanotoxicity: From Bench to Bedside
Published in Advanced drug delivery reviews (2012)Get full text
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Static and Dynamic Disorder Observed in the Phase Transition Behavior of Individual Small Unilamellar Vesicles
Published in Biophysical journal (01-02-2011)Get full text
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Phase Transitions in Single Nano-Vesicles
Published in Biophysical journal (01-02-2009)Get full text
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Material properties in complement activation: Complement Monitoring of Nanomedicines and Implants
Published in Advanced drug delivery reviews (2011)Get full text
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