Search Results - "Wible, James H."

Bioeffects Considerations for Diagnostic Ultrasound Contrast Agents by Miller, Douglas L., Averkiou, Michalakis A., Brayman, Andrew A., Everbach, E. Carr, Holland, Christy K., Wible, James H., Wu, Junru

“…Diagnostic ultrasound contrast agents have been developed for enhancing the echogenicity of blood and for delineating other structures of the body. Approved…”
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Biodistribution of diclofenac following repeated topical applications of two diclofenac sodium formulations to minipigs by Wible Jr, James H., Barrett, Thomas, Devarakonda, Krishna, Giuliani, Michael

“…ABSTRACT This study evaluated diclofenac concentrations in plasma, selected hind limb tissues and synovial fluid after repeated topical applications of two…”
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Measurement of Serum Calcium Concentration After Administration of Four Gadolinium-Based Contrast Agents to Human Volunteers by Brown, Jeffery J, Hynes, Michael R, Wible, James H., Jr

“…The purpose of this study was to use three analytic methods to measure serum calcium concentration to assess the magnitude and time course of the effects of…”
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Detection of Individual Microbubbles of Ultrasound Contrast Agents: Imaging of Free-Floating and Targeted Bubbles by Klibanov, Alexander L, Rasche, Peter T, Hughes, Michael S, Wojdyla, Jolette K, Galen, Karen P, Wible, James H, Brandenburger, Gary H

“…RATIONALE AND OBJECTIVES:During echo examinations with microbubble contrast, individual “dots” of ultrasound reflection can be visualized. To address the…”
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Microbubbles induce renal hemorrhage when exposed to diagnostic ultrasound in anesthetized rats by Wible, Jr, James H, Galen, Karen P, Wojdyla, Jolette K, Hughes, Michael S, Klibanov, Alexander L, Brandenburger, Gary H

“…The generation of ultrasound (US) bioeffects using a clinical imaging system is controversial. We tested the hypothesis that the presence of microbubbles in…”
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Performance of Delayed-Enhancement Magnetic Resonance Imaging With Gadoversetamide Contrast for the Detection and Assessment of Myocardial Infarction : An International, Multicenter, Double-Blinded, Randomized Trial by KIM, Raymond J, ALBERT, Timothy S. E, WIBLE, James H, ELLIOTT, Michael D, ALLEN, John C, LEE, Jennifer C, PARKER, Michele, NAPOLI, Alicia, JUDD, Robert M

“…The identification and assessment of myocardial infarction (MI) are important for therapeutic and prognostic purposes, yet current recommended diagnostic…”
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Pharmacokinetics of gadoversetamide injection, a gadolinium-based contrast agent, in pediatric patients by Wible, James H, Tata, Prasad N.V, Napoli, Alicia M, Lowe, Lisa H, Kearns, Gregory L

“…Abstract Objective The pharmacokinetics of gadoversetamide were examined in pediatric patients scheduled to undergo contrast-enhanced MRI of the central…”
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Detection of individual microbubbles of an ultrasound contrast agent: fundamental and pulse inversion imaging by Klibanov, Alexander L, Rasche, Peter T, Hughes, Michael S, Wojdyla, Jolette K, Galen, Karen P, Wible, Jr, James H, Brandenburger, Gary H

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Measurement of serum calcium concentration after administration of gadoversetamide in dogs by Wible, Jr, James H, Hynes, Michael R

“…To measure serum calcium concentration with three different analytic methods after administration of gadoversetamide and three other gadolinium chelates in…”
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The safety and efficacy of neuroimaging with gadoversetamide injection in pediatric patients by Lowe, Lisa H., Kearns, Gregory L., Wible, James H.

“…ABSTRACT Objective: The safety and efficacy of gadoversetamide injection (OptiMARK*) was examined in pediatric patients referred for magnetic resonance imaging…”
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Destruction of contrast agent microbubbles in the ultrasound field: the fate of the microbubble shell and the importance of the bubble gas content by Klibanov, Alexander L, Hughes, Michael S, Wojdyla, Jolette K, Wible, Jr, James H, Brandenburger, Gary H

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Safety assessment of gadoversetamide (OptiMARK®) administered by power injector by Abdou, Nancy, Napoli, Alicia M., Hynes, Michael R., Allen Jr, John C., Wible Jr, James H.

“…Purpose To evaluate the safety of OptiMARK® (gadoversetamide injection) administered via power injector. Materials and Methods The study population included…”
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Pharmacokinetics and Safety of the MRI Contrast Agent Gadoversetamide Injection (Optimark) in Healthy Pediatric Subjects by Baker, James F, Kratz, Linda C, Stevens, Gary R, Wible, James H

“…RATIONAL AND OBJECTIVE:This clinical trial examined the pharmacokinetics of gadoversetamide, a magnetic resonance imaging contrast agent, in normal pediatric…”
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Cardiac magnetic resonance imaging safety following percutaneous coronary intervention by Curtis, Jason W., Lesniak, Donna C., Wible, James H., Woodard, Pamela K.

“…In the first 8 weeks after percutaneous coronary intervention (PCI), possible negative interactions exist between the cardiac magnetic resonance (CMR) imaging…”
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Cardiovascular Effects Caused by Rapid Administration of Gadoversetamide Injection in Anesthetized Dogs by WIBLE, JAMES H, GALEN, KAREN P, WOJDYLA, JOLETTE K

“…Wible JH, Galen KP, Wojdyla J. Cardiovascular effects caused by rapid administration of gadoversetamide injection in anesthetized dogs. Invest Radiol…”
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Characterization of viable and nonviable myocardium at MR imaging: comparison of gadolinium-based extracellular and blood pool contrast materials versus manganese-based contrast materials in a rat myocardial infarction model by Flacke, Sebastian, Allen, John S, Chia, Jon M, Wible, James H, Periasamy, M Peri, Adams, Max D, Adzamli, I Kofi, Lorenz, Christine H

“…To determine the contrast agent behavior of gadolinium-based (extracellular and albumin-binding) and manganese-based contrast media for late-enhancement…”
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Cardiovascular Effects of β-Carbolines in Conscious Rats by Wible, James H., Luft, Friedrich C., Stock, Daniel, DiMicco, Joseph A.

“…The β-carbolines have a high affinity for the benzodiazepine receptor, where they demonstrate actions opposite to those of the benzodiazepines and elicit…”
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Toxicological Assessment of Gadoversetamide Injection (OptiMARK®), a New Contrast-Enhancement Agent for Use in Magnetic Resonance Imaging by WIBLE, JAMES H, TROUP, CATHERINE M, HYNES, MICHAEL R, GALEN, KAREN P, MacDONALD, JANICE R, BARCO, STEVEN J, WOJDYLA, JOLETTE K, PERIASAMY, M PERI, ADAMS, MAX D

“…Wible JH, Troup CM, Hynes MR, et al. Toxicological assessment of gadoversetamide injection (OptiMARK®), a new contrast-enhancement agent for use in magnetic…”
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Direct Video-Microscopic Observation of the Dynamic Effects of Medical Ultrasound on Ultrasound Contrast Microspheres by KLIBANOV, ALEXANDER L, FERRARA, KATHERINE W, HUGHES, MICHAEL S, WIBLE, JAMES H, WOJDYLA, JOLETTE K, DAYTON, PAUL A, MORGAN, KAREN E, BRANDENBURGER, GARY H

“…RATIONALE AND OBJECTIVES.Ultrasound can cause destruction of microbubble contrast agents used to enhance medical ultrasound imaging. This study sought to…”
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Abstract 5516: Biodistribution of liposomal docetaxel prodrug MNK-010 in mice bearing A549 human NSCLC xenografts by Fitch, Richard M., Wible, James H., Blackledge, James A., McGhee, William D.

“…The anti-mitotic taxanes belong to one of the most important families of anticancer drugs that have broad anti-tumor activity and are widely used for a variety…”
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