Search Results - "Wiaderna, D"
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Behavioral Effects Following Subacute Inhalation Exposure to m-Xylene or Trimethylbenzene in the Rat : A Comparative Study
Published in Neurotoxicology (Park Forest South) (01-02-2001)“…Trimethylbenzene (TMB), like xylene (dimethylbenzene), is a significant constituent of some industrial solvent mixtures. In earlier studies, we found that in…”
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Effects of repeated exposure to toluene or amphetamine on locomotor activity in rats
Published in International journal of occupational medicine and environmental health (2000)“…This study was performed to find out whether repeated exposure to toluene might lead to behavioural sensitization estimated on the basis of spontaneous…”
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3
Changes in electrocortical arousal following acute trimethylbenzene administration in rats
Published in International journal of occupational medicine and environmental health (2000)“…The purpose of this investigation was to compare the neurotoxic potential of trimethylbenzene (TMB) isomers (the solvents) with that of benzene derivatives…”
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Behavioural changes following a four-week inhalation exposure to hemimellitene (1,2,3-trimethylbenzene) in rats
Published in International journal of occupational medicine and environmental health (1998)“…Trimethylbenzene isomers (TMBs): 1,2,4-TMB (pseudocumene--PS), 1,2,3-TMB (hemimellitene--HM) and 1,3,5-TMB (mesitylene--MES) are important constituents of…”
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Neurotoxicity assessment of selected organic solvents based on spontaneous and evoked cortical and hippocampal activity in rats
Published in International journal of occupational medicine and environmental health (1999)“…In a series of acute experiments on rats the potential of toluene, mesitylene, hemimellitene and pseudocumene to affect the CNS function was assessed following…”
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Spontaneous spike-wave discharges in rat neocortex and their relation to behaviour
Published in Acta neurobiologiae experimentalis (01-01-2000)“…A certain proportion of laboratory rats of various strains show spontaneous nonconvulsive ECoG seizures in the form of bursts of spike-and-wave discharges…”
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Development of spontaneous, age-related nonconvulsive seizure electrocortical activity and radial-maze learning after exposure to m-xylene in rats
Published in International journal of occupational medicine and environmental health (1995)“…It has been hypothesized that exposure to neurotoxins may result in accelerated ageing of the central nervous system (CNS). The present study investigated the…”
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Spontaneous seizure electrocortical activity in rats: relation to arousal level
Published in Acta neurobiologiae experimentalis (01-01-1994)“…The relationship between neocortical high voltage spindle activity (HVS) and the level of arousal (state of vigilance) was investigated in imp-DAK rats. Two…”
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Effects of repeated systemic penicillin injections on nonconvulsive and convulsive epileptic seizures in the rat
Published in Acta neurobiologiae experimentalis (01-01-1995)“…Changes in the spontaneous and induced epileptic activity in the course of repetitive systemic i.p. administration of crystalline penicillin (Pc) were examined…”
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Development of the age-related spontaneous spike-wave discharges in rat neocortex and exposure to a model neurotoxin
Published in Acta neurobiologiae experimentalis (01-01-1995)“…In laboratory rats an epileptic-like spontaneous neocortical activity in the form of bursts of spike and wave discharges (SWD) develops gradually with age…”
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Neurobehavioural functions in adult progeny of rat mothers exposed to methylmercury or 2,2', 4,4', 5,5'-hexachlorobiphenyl (PCB 153) alone or their combination during gestation and lactation
Published in International journal of occupational medicine and environmental health (01-01-2009)“…Objectives: Methylmercury (MeHg) and polychlorinated biphenyls (PCBs) are ubiquitous environmental pollutants. Both are neurotoxic, especially for the…”
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Opposite effects of T- and L-type Ca2+ channels blockers in generalized absence epilepsy
Published in European journal of pharmacology (20-10-2000)Get full text
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Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy
Published in European journal of pharmacology (20-10-2000)“…The role of the T-type Ca(2+) channel blocker, ethosuximide, the L-type Ca(2+) channel blocker, nimodipine and L-type Ca(2+) channel opener, BAY K8644 (1,4…”
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Effects of stress pretreatment on the dynamics of blood cholinesterase activity after exposure to an organophosphorus pesticide in the rat
Published in Annals of Agricultural and Environmental Medicine (2010)“…A single i.p. administration of 1.0 mg/kg of chlorphenvinphos (CVP), an organophosphorus pesticide, results in an acute stress response, evidenced by a marked…”
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Alteration in behavioral sensitivity to amphetamine after treatment with oxotremorine: Effect of dose and test environment
Published in Behavioural brain research (17-12-2003)“…Our earlier experiment revealed that rats pretreated once with an anticholinesterase develop hyposensitivity to amphetamine (AMPH). One of the likely causes of…”
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Contrasting effects of 4-week inhalation exposure to pseudocumene or hemimellitene on sensitivity to amphetamine and propensity to amphetamine sensitization in the rat
Published in International journal of occupational medicine and environmental health (01-01-2010)“…Objectives: Some data suggest that increased behavioural sensitivity to psychostimulants may develop after exposure to volatile chemicals in common use. The…”
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Amphetamine- and scopolamine-induced locomotor activity following treatment with chlorphenvinphos or chlorphyriphos in rats
Published in International journal of occupational medicine and environmental health (2005)“…Effects of acute exposure to organophosphorous pesticides (OPs), chlorphenvinphos (CVP) or chlorphyriphos (CPF) on amphetamine (AMPH)- or scopolamine…”
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Assessment of long-term effects of exposure to toluene based on the analysis of selected behavioral responses with particular reference to the ability to trigger behavioral hypersensitivity in rats
Published in International journal of occupational medicine and environmental health (2002)“…Toluene is a major component of numerous commercial organic solvent formulations. It is often listed among the chemicals capable of producing the organic…”
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Assessment of long-term neurotoxic effects of exposure to mesitylene (1,3,5-trimethylbenzene) based on the analysis of selected behavioral responses
Published in International journal of occupational medicine and environmental health (2002)“…Trimetylbenzene isomers: pseudocumene, hemimellitene and mesitylene, are major components of numerous commercial solvents and high-grade fuels. In our earlier…”
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Pseudocumene in brain, liver, lung and blood of rats after single and repeated inhalation exposure
Published in International journal of occupational medicine and environmental health (2003)“…Male Wistar rats were exposed to pseudocumene vapors at nominal concentration of 25, 100 or 250 ppm in the dynamic inhalation chambers for 6 h or 4 weeks (6…”
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