Search Results - "Why, H J"

Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischaemic or valvar heart disease by de Belder, A. J., Radomski, M. W., Why, H. J., Richardson, P. J., Martin, J. F.

“…OBJECTIVE--To determine the activity of the calcium-dependent constitutive (cNOS) and calcium-independent inducible nitric oxide (iNOS) synthases in heart…”
Get full text

Clinical and prognostic significance of detection of enteroviral RNA in the myocardium of patients with myocarditis or dilated cardiomyopathy by WHY, H. J. F, MEANY, B. T, RICHARDSON, P. J, OLSEN, E. G. J, BOWLES, N. E, CUNNINGHAM, L, FREEKE, C. A, ARCHARD, L. C

“…Enteroviral RNA sequences have been demonstrated in the myocardium of patients with myocarditis or dilated cardiomyopathy from presentation to end-stage…”
Get full text

The effects of alcohol on the heart by Patel, V B, Why, H J, Richardson, P J, Preedy, V R

“…We have discussed in this review many features and possible mechanisms responsible for the development of alcoholic cardiomyopathy. The evidence suggests that…”
Get more information

Molecular probes for detection of persisting enterovirus infection of human heart and their prognostic value by Archard, L C, Bowles, N E, Cunningham, L, Freeke, C A, Olsen, E G, Rose, M L, Meany, B, Why, H J, Richardson, P J

“…Enteroviruses are well recognized in the aetiology of myocarditis. Molecular hybridization using enterovirus group-specific probes shows that virus can be…”
Get more information

Circulating antibodies to cardiac protein-acetaldehyde adducts in alcoholic heart muscle disease by Harcombe, A A, Ramsay, L, Kenna, J G, Koskinas, J, Why, H J, Richardson, P J, Weissberg, P L, Alexander, G J

“…1. Serum samples from patients with alcoholic heart muscle disease and from control subjects with and without heart disease who did not drink to excess were…”
Get more information

Effect of carvedilol on left ventricular function and mass in hypertension by Why, H J, Richardson, P J

“…The effects of carvedilol, a nonselective beta-blocker with peripheral vasodilator action, on left ventricular function and mass in essential hypertension were…”
Get more information

Nitric oxide synthase activities in human myocardium by de Belder, A J, Radomski, M W, Why, H J, Richardson, P J, Bucknall, C A, Salas, E, Martin, J F, Moncada, S

“…Myocardial constitutive and inducible nitric oxide (NO) synthase activities were measured in right ventricular tissue from 17 patients with dilated…”
Get more information

Characterization of coxsackie B virus RNA in myocardium from patients with dilated cardiomyopathy by nucleotide sequencing of reverse transcription-nested polymerase chain reaction products by Archard, Leonard C., Khan, Mahboob A., Soteriou, Bambos A., Zhang, Hongyi, Why, Howard J.F., Robinson, Nicholas M.K., Richardson, Peter J.

“…This study was performed to detect and characterize the enterovirus present in myocardium of some patients with heart muscle disease by nucleotide sequencing…”
Get full text

Cardiac protein abnormalities in dilated cardiomyopathy detected by two-dimensional polyacrylamide gel electrophoresis by Corbett, J M, Why, H J, Wheeler, C H, Richardson, P J, Archard, L C, Yacoub, M H, Dunn, M J

“…The aim of the investigation was to determine whether there are specific global quantitative and qualitative changes in protein expression in heart tissue from…”
Get more information

Alcohol and the heart : biochemical alterations by PREEDY, V. R, PATEL, V. B, WHY, H. J. F, CORBETT, J. M, DUNN, M. J, RICHARDSON, P. J

“…A considerable amount of attention has focused on the cardiovascular events associated with ethanol consumption. The available evidence suggests that moderate…”
Get full text

Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension by Mantle, D, Patel, V.B, Why, H.J.F, Ahmed, S, Rahman, I, MacNee, W, Wassif, W.S, Richardson, P.J, Preedy, V.R

“…The objective of this investigation was to compare changes in antioxidant status (together with other metabolites relevant to hypertension) in plasma and…”
Get full text

Ethanol toxicity and cardiac protein synthesis in vivo by Preedy, V R, Siddiq, T, Why, H J, Richardson, P J

“…Long- and short-term alcohol consumption induce a variety of cardiovascular changes, including alterations in hemodynamic variables and tissue biochemistry. In…”
Get more information

A potassium channel opener as monotherapy in chronic stable angina pectoris: comparison with placebo by Why, H J, Richardson, P J

“…The vasodilating agent nicorandil produces marked coronary artery dilatation by a number of mechanisms including an increase in cyclic guanosine monophosphate,…”
Get more information

Modified release verapamil induced cardiogenic shock by Nanda, U, Ashish, A, Why, H J F

“…Cardiogenic shock due to acute myocardial infarction is commonly seen in the accident and emergency department. Refractory cardiogenic shock has been reported…”
Get full text

Dilated cardiomyopathy--new insights into the pathogenesis by Why, H J, Archard, L C, Richardson, P J

“…There is increasing evidence for a viral aetiology in many patients with dilated cardiomyopathy, although the term viral heart disease is not currently…”
Get full text

Left atrial spontaneous echo contrast assessed by TEE in patients with either native mitral valve disease or mitral valve replacement by Michalis, L K, Thomas, M R, Smyth, D W, Why, H J, Monaghan, M J, Jewitt, D E

“…The incidence of spontaneous echo contrast in the left atrium, the factors with which it is associated, and its clinical significance were studied in 128…”
Get more information

Antioxidant status in hypertension and effects of angiotensin converting enzyme inhibition by Why, H J, Ansell, H, Patel, V B, Wassif, W S, Reeves, J, Siddiq, T, Richardson, P J, Preedy, V R

Get more information

Virus infection and dilated cardiomyopathy by Richardson, P J, Why, H J, Archard, L C

“…The implication of virus infection in the pathogenesis of dilated cardiomyopathy has been strengthened by a number of studies demonstrating a progression from…”
Get full text

Effects of angiotensin converting enzyme inhibition on cardiac collagen in hypertensive and normotensive rats by Why, H J, Patel, V B, Richardson, P J, Preedy, V R

Get more information

Protein turnover in alcoholism: should it be considered as a whole body event or tissue specific phenomena? by Preedy, V R, Reilly, M E, Why, H J, Bonner, A B, Richardson, P J

Get more information