Search Results - "Whorton, Elbert B."
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Protective effect of apigenin on radiation-induced chromosomal damage in human lymphocytes
Published in Mutation research (01-08-2005)“…The potential use of flavonoids as a radioprotector is of increasing interest because of their high antioxidant activity and abundance in the diet. The aim of…”
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2
Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model
Published in Pathogens (Basel) (22-09-2020)“…The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of…”
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3
Persistence of apoptosis and inflammatory responses in the heart and bone marrow of mice following whole-body exposure to 28Silicon (28Si) ions
Published in Radiation and environmental biophysics (01-08-2013)“…It has been well established that the bone marrow (BM) is a radiosensitive tissue, but the radiosensitivity of the heart is poorly understood. In this study,…”
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4
Pathogenesis of extra efferent vessel development in diabetic glomeruli
Published in Human pathology (01-08-2007)“…Summary The development of extra efferent vessels (EEV) is a little-known feature of diabetic glomerulopathy. The only previous large study [Min W, Yamanaka N…”
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5
Hemodynamic effects of anthrax toxins in the rabbit model and the cardiac pathology induced by lethal toxin
Published in Toxins (01-06-2011)“…Anthrax lethal toxin (LeTx) and edema toxin (EdTx) have been shown to alter hemodynamics in the rodent model, while LeTx primarily is reported to induce…”
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6
Induction of genomic instability after an acute whole-body exposure of mice to 56Fe ions
Published in Advances in space research (01-10-2009)“…The purpose of this study was to evaluate dose–response relationships for the in vivo induction of micronuclei (MN) as a measure of both initial radiation…”
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7
Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice
Published in Microbes and infection (01-08-2008)“…In this study, we examined the tissue specificity of inflammatory and oxidative responses and mitochondrial dysfunction in mice infected by Trypanosoma cruzi…”
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Induction of Chronic Inflammation and Altered Levels of DNA Hydroxymethylation in Somatic and Germinal Tissues of CBA/CaJ Mice Exposed to (48)Ti Ions
Published in Frontiers in oncology (27-06-2016)“…Although the lung is one of the target organs at risk for cancer induction from exposure to heavy ions found in space, information is insufficient on…”
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Persistent depletion of plasma gelsolin (pGSN) after exposure of mice to heavy silicon ions
Published in Life sciences in space research (01-05-2018)“…•The magnitude of pGSN depletion was dependent on radiation dose at both harvest times.•Increased levels of cell death were found in the lung of mice with…”
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Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn‐ and smoke‐induced acute lung injury
Published in British journal of pharmacology (01-11-2009)“…Background and purpose: The present study investigated whether the pathophysiological changes induced by burn and smoke inhalation are modulated by parenteral…”
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11
Effects of 100MeV protons delivered at 0.5 or 1cGy/min on the in vivo induction of early and delayed chromosomal damage
Published in Mutation research (30-08-2013)“…Little is known about in vivo cytogenetic effects of protons delivered at the dose and dose rates encountered in space. We determined the effects of 100MeV…”
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Effects of 100 MeV protons delivered at 0.5 or 1 cGy/min on the in vivo induction of early and delayed chromosomal damage
Published in Mutation research. Genetic toxicology and environmental mutagenesis (30-08-2013)“…Little is known about in vivo cytogenetic effects of protons delivered at the dose and dose rates encountered in space. We determined the effects of 100 MeV…”
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13
γ-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury
Published in Free radical biology & medicine (15-08-2008)“…Fire accident victims who sustain both thermal injury to skin and smoke inhalation have gross evidence of systemic and pulmonary oxidant damage and acute lung…”
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No Evidence for the In Vivo Induction of Genomic Instability by Low Doses of CS Gamma Rays in Bone Marrow Cells of BALB/CJ and C57BL/6J Mice
Published in Dose-response (2012)“…In spite of extensive research, assessment of potential health risks associated with exposure to low-dose (≤ 0.1 Gy) radiation is still challenging. We…”
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Effects of Early Neuronal and Delayed Inducible Nitric Oxide Synthase Blockade on Cardiovascular, Renal, and Hepatic Function in Ovine Sepsis
Published in Anesthesiology (Philadelphia) (01-12-2010)“…Recent evidence suggests that nitric oxide produced via the neuronal nitric oxide synthase is involved mainly in the early response to sepsis, whereas nitric…”
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Sensorimotor adaptation training's effect on head stabilization in response to a lateral perturbation in older adults
Published in Journal of aging and physical activity (01-07-2013)“…The goal of this study was to determine if exposure to sensorimotor adaptation training improved head stabilization in older adults. Sixteen participants, age…”
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Predictive role of arterial carboxyhemoglobin concentrations in ovine burn and smoke inhalation-induced lung injury
Published in Experimental lung research (01-05-2011)“…ABSTRACT Inhalation injury frequently occurs in burn patients and contributes to the morbidity and mortality of these injuries. Arterial carboxyhemoglobin has…”
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Physiologic Responses of Dutch Belted Rabbits Infected with Inhalational Anthrax
Published in Comparative medicine (01-06-2009)“…Bacillus anthracis, the causative agent of anthrax, is a category A priority pathogen that causes extensive damage in humans. For this reason, B. anthracis has…”
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Effects of Sensorimotor Adaptation Training on Functional Mobility in Older Adults
Published in The journals of gerontology. Series B, Psychological sciences and social sciences (01-09-2008)“…The goal of this study was to determine if prolonged exposure to perceptual-motor mismatch increased adaptability and retention of balance in older adults…”
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Human genotoxicity: pesticide applicators and phosphine
Published in Science (American Association for the Advancement of Science) (13-10-1989)“…Fumigant applicators who, 6 weeks to 3 months earlier, were exposed to phosphine, a common grain fumigant, or to phosphine and other pesticides had…”
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