Search Results - "Whitworth, Judith A."

Economic hardship associated with managing chronic illness: a qualitative inquiry by Jeon, Yun-Hee, Essue, Beverley, Jan, Stephen, Wells, Robert, Whitworth, Judith A

“…Chronic illness and disability can have damaging, even catastrophic, socioeconomic effects on individuals and their households. We examined the experiences of…”
Get full text

How Do Glucocorticoids Cause Hypertension: Role of Nitric Oxide Deficiency, Oxidative Stress, and Eicosanoids by Ong, Sharon L.H., BSc(Med), MBBS, FRACP, Whitworth, Judith A., AC, MBBS, DSc, MD, PhD, FRACP

“…The exact mechanism by which glucocorticoid induces hypertension is unclear. Several mechanisms have been proposed, although there is evidence against the role…”
Get full text

Blood pressure and control of cardiovascular risk by Whitworth, Judith A

“…Two key early 20th century notions, the first the primacy of diastolic pressure in determining risk, and the second that hypertension is a discrete disorder,…”
Get full text

Cushing, Cortisol, and Cardiovascular Disease by Whitworth, Judith A, Mangos, George J, Kelly, John J

“…Cushing’s syndrome of glucocorticoid excess is named after the eminent Boston neurosurgeon Harvey W. Cushing (1869-1939). The recognition that glucocorticoid…”
Get full text

2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension by Whitworth, Judith A

“…OBJECTIVEHypertension is estimated to cause 4.5% of current global disease burden and is as prevalent in many developing countries, as in the developed world…”
Get full text

In pursuit of patient care, research and health policy: today's research is tomorrow's practice and policy by Whitworth, Judith A

Get full text

REACTIVE OXYGEN SPECIES AND GLUCOCORTICOID-INDUCED HYPERTENSION by Ong, Sharon LH, Zhang, Yi, Whitworth, Judith A

“…SUMMARY 1 There is increasing evidence for a role of oxidative stress and nitric oxide deficiency in experimental glucocorticoid‐induced hypertension, as…”
Get full text

Cardiovascular consequences of cortisol excess by Whitworth, Judith A, Williamson, Paula M, Mangos, George, Kelly, John J

Get full text

The role of 20-hydroxyeicosatetraenoic acid in adrenocorticotrophic hormone and dexamethasone-induced hypertension by YI ZHANG, WU, Jason H. Y, VICKERS, Janine J, ONG, Sharon L. H, TEMPLE, Suzanna E. L, MORI, Trevor A, CROFT, Kevin D, WHITWORTH, Judith A

“…20-hydroxyeicosatetraenoic acid (20-HETE) is a potent constrictor in small arteries and also has natriuretic properties. Urinary 20-HETE excretion is increased…”
Get full text

The nitric oxide system in glucocorticoid-induced hypertension by Whitworth, Judith A, Schyvens, Christopher G, Zhang, Yi, Andrews, Miles C, Mangos, George J, Kelly, John J

“…The blood pressure-raising effects of adrenocortical steroids with predominantly glucocorticoid activity, both naturally occurring and synthetic, are well…”
Get full text

Best practices in use of research evidence to inform health decisions by Whitworth, Judith A

“…The WHO Advisory Committee on Health Research (ACHR) is committed to the notion that WHO should exemplify best practice in use of research evidence to inform…”
Get full text

Should eponyms be abandoned? No by Whitworth, Judith A

“…Medicine has been enthusiastic in naming tests, symptoms, and diseases after their discovers. Alexander Woywodt and Eric Matteson argue that eponyms are no…”
Get full text

Decreased renal expression of nitric oxide synthase isoforms in adrenocorticotropin-induced and corticosterone-induced hypertension by LOU, Yi-Kun, CHENG WEN, MING LI, ADAMS, David J, WANG, Min-Xia, FENG YANG, MORRIS, Brian J, WHITWORTH, Judith A

“…Administration of adrenocorticotropic hormone (ACTH) leads to the development of hypertension. Because glucocorticoids can affect the nitric oxide system at…”
Get full text

The role of corticosterone in corticotrophin (ACTH)-induced hypertension in the rat by Mangos, George J, Turner, Steven W, Fraser, Tafline B, Whitworth, Judith A

“…OBJECTIVECorticotrophin (ACTH)-induced hypertension in the rat is prevented by L- but not D-arginine. We examined the effects of exogenous corticosterone in…”
Get full text

Role Of Nitric Oxide In Adrenocorticotrophin-Induced Hypertension: L-Arginine Effects Reversed By N-Nitro-L-Arginine by Wen, Cheng, Li, Ming, Whitworth, Judith A

“…SUMMARY 1. L‐Arginine prevents adrenocorticotrophin (ACTH)‐induced hypertension in the rat. To confirm that this effect is mediated through the nitric oxide…”
Get full text

Effects of oral l-arginine on plasma nitrate and blood pressure in cortisol-treated humans by Kelly, John J, Williamson, Paula, Martin, Allison, Whitworth, Judith A

“…OBJECTIVEThe aim of this study was to determine whether cortisol-induced hypertension can be reversed by co-administration of oral l-arginine. STUDY…”
Get full text

Lipopolysaccharide Reverses Adrenocorticotrophic Hormone-Induced Hypertension in the Rat by ZHANG, Yi, Christopher, G. SCHYVENS, Katja, U.S. McKENZIE, Brian, J. MORRIS, Judith, A. WHITWORTH

“…Lipopolysaccharide (LPS) was used to stimulate nitric oxide (NO) release and investigate the effect of endogenous NO on adrenocorticotrophic hormone…”
Get full text

THE NITRIC OXIDE SYSTEM AND CORTISOL-INDUCED HYPERTENSION IN HUMANS by Kelly, John J, Tam, Sim H, Williamson, Paula M, Lawson, Jane, Whitworth, Judith A

“…SUMMARY 1. The aim of the present study was to assess the role of the nitric oxide (NO) system in cortisol‐induced hypertension in humans. 2. Plasma and…”
Get full text

Who said that? by Whitworth, Judith A

“…Contemporary technology allows frequent citation updates so that it is possible at the click of a mouse for a researcher to ascertain who in the last week has…”
Get full text

The Effect of Alpha-Lipoic Acid on Mitochondrial Superoxide and Glucocorticoid-Induced Hypertension by Ong, Sharon L. H., Vohra, Harpreet, Zhang, Yi, Sutton, Matthew, Whitworth, Judith A.

“…Aims. To examine the effect of alpha-lipoic acid, an antioxidant with mitochondrial superoxide inhibitory properties, on adrenocorticotrophic hormone-…”
Get full text