Search Results - "Whittles, Lilith K"
-
1
Estimating the fitness cost and benefit of cefixime resistance in Neisseria gonorrhoeae to inform prescription policy: A modelling study
Published in PLoS medicine (31-10-2017)“…Gonorrhoea is one of the most common bacterial sexually transmitted infections in England. Over 41,000 cases were recorded in 2015, more than half of which…”
Get full text
Journal Article -
2
Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England
Published in Nature communications (17-07-2023)“…As the SARS-CoV-2 pandemic progressed, distinct variants emerged and dominated in England. These variants, Wildtype, Alpha, Delta, and Omicron were…”
Get full text
Journal Article -
3
Children’s role in the COVID-19 pandemic: a systematic review of early surveillance data on susceptibility, severity, and transmissibility
Published in Scientific reports (06-07-2021)“…SARS-CoV-2 infections have been reported in all age groups including infants, children, and adolescents. However, the role of children in the COVID-19 pandemic…”
Get full text
Journal Article -
4
A dynamic power-law sexual network model of gonorrhoea outbreaks
Published in PLoS computational biology (01-03-2019)“…Human networks of sexual contacts are dynamic by nature, with partnerships forming and breaking continuously over time. Sexual behaviours are also highly…”
Get full text
Journal Article -
5
Comparing the responses of the UK, Sweden and Denmark to COVID-19 using counterfactual modelling
Published in Scientific reports (11-08-2021)“…The UK and Sweden have among the worst per-capita COVID-19 mortality in Europe. Sweden stands out for its greater reliance on voluntary, rather than mandatory,…”
Get full text
Journal Article -
6
Author Correction: Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England
Published in Nature communications (07-12-2023)Get full text
Journal Article -
7
Genomic Analysis and Comparison of Two Gonorrhea Outbreaks
Published in mBio (28-06-2016)“…Gonorrhea is a sexually transmitted disease causing growing concern, with a substantial increase in reported incidence over the past few years in the United…”
Get full text
Journal Article -
8
-
9
Epidemiological Trends of Antibiotic Resistant Gonorrhoea in the United Kingdom
Published in Antibiotics (Basel) (13-07-2018)“…Gonorrhoea is one of the most common sexually-transmitted bacterial infections, globally and in the United Kingdom. The levels of antibiotic resistance in…”
Get full text
Journal Article -
10
Public health impact and cost-effectiveness of gonorrhoea vaccination: an integrated transmission-dynamic health-economic modelling analysis
Published in The Lancet infectious diseases (01-07-2022)“…Gonorrhoea is a rapidly growing public health threat, with rising incidence and increasing drug resistance. Evidence that the MeNZB and four-component…”
Get full text
Journal Article -
11
Epidemiological analysis of the Eyam plague outbreak of 1665–1666
Published in Proceedings of the Royal Society. B, Biological sciences (11-05-2016)“…Plague, caused by the bacterium Yersinia pestis, is one of the deadliest infectious diseases in human history, and still causes worrying outbreaks in Africa…”
Get full text
Journal Article -
12
Assessment of the Potential of Vaccination to Combat Antibiotic Resistance in Gonorrhea: A Modeling Analysis to Determine Preferred Product Characteristics
Published in Clinical infectious diseases (05-11-2020)“…Abstract Background Gonorrhea incidence is increasing rapidly in many countries, while antibiotic resistance is making treatment more difficult. Combined with…”
Get full text
Journal Article -
13
The potential role of the 4CMenB vaccine in combating gonorrhoea: the need for nuance in interpreting the DOXYVAC trial
Published in The Lancet infectious diseases (01-09-2024)“…On Nov 10, 2023, the Joint Committee on Vaccination and Immunisation advised the UK to use the 4CMenB meningitis B vaccine to prevent gonorrhoea in men who…”
Get full text
Journal Article -
14
Non-pharmaceutical interventions, vaccination, and the SARS-CoV-2 delta variant in England: a mathematical modelling study
Published in The Lancet (British edition) (13-11-2021)“…England's COVID-19 roadmap out of lockdown policy set out the timeline and conditions for the stepwise lifting of non-pharmaceutical interventions (NPIs) as…”
Get full text
Journal Article -
15
Health-Economic Value of Vaccination Against Group A Streptococcus in the United States
Published in Clinical infectious diseases (23-03-2022)“…Abstract Background Vaccines are needed to reduce the burden of group A Streptococcus (GAS). We assessed the potential health-economic value of GAS vaccines…”
Get full text
Journal Article -
16
We need estimates of gonorrhoea vaccine protection and symptomaticity by sex and anatomical site
Published in The Lancet infectious diseases (01-07-2022)“…To make the best use of limited public health resources, we need to determine the appropriate groups to be offered gonorrhoea vaccination—eg, men who have sex…”
Get full text
Journal Article -
17
Cost-effectiveness of 4CMenB vaccination against gonorrhea: importance of dosing schedule, vaccine sentiment, targeting strategy, and duration of protection
Published in The Journal of infectious diseases (17-04-2024)“…Observational evidence suggests the 4CMenB meningococcal vaccine may partially protect against gonorrhea, with one dose being two-thirds as protective as two…”
Get full text
Journal Article -
18
Potential impact of the COVID-19 pandemic on HIV, tuberculosis, and malaria in low-income and middle-income countries: a modelling study
Published in The Lancet global health (01-09-2020)“…COVID-19 has the potential to cause substantial disruptions to health services, due to cases overburdening the health system or response measures limiting…”
Get full text
Journal Article -
19
The potential public health consequences of COVID-19 on malaria in Africa
Published in Nature medicine (01-09-2020)“…The burden of malaria is heavily concentrated in sub-Saharan Africa (SSA) where cases and deaths associated with COVID-19 are rising 1 . In response, countries…”
Get full text
Journal Article -
20
Within-country age-based prioritisation, global allocation, and public health impact of a vaccine against SARS-CoV-2: A mathematical modelling analysis
Published in Vaccine (21-05-2021)“…•The global dose supply of COVID-19 vaccines will be constrained in 2021.•Within a country, prioritising doses to protect those at highest mortality risk is…”
Get full text
Journal Article