Search Results - "Whittle, C."

Frequency-Dependent Squeezing for Advanced LIGO by McCuller, L, Whittle, C, Ganapathy, D, Komori, K, Tse, M, Fernandez-Galiana, A, Barsotti, L, Fritschel, P, MacInnis, M, Matichard, F, Mason, K, Mavalvala, N, Mittleman, R, Yu, Haocun, Zucker, M E, Evans, M

“…The first detection of gravitational waves by the Laser Interferometer Gravitational-Wave Observatory (LIGO) in 2015 launched the era of gravitational-wave…”
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Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer by Duncan, James S., Whittle, Martin C., Nakamura, Kazuhiro, Abell, Amy N., Midland, Alicia A., Zawistowski, Jon S., Johnson, Nancy L., Granger, Deborah A., Jordan, Nicole Vincent, Darr, David B., Usary, Jerry, Kuan, Pei-Fen, Smalley, David M., Major, Ben, He, Xiaping, Hoadley, Katherine A., Zhou, Bing, Sharpless, Norman E., Perou, Charles M., Kim, William Y., Gomez, Shawn M., Chen, Xin, Jin, Jian, Frye, Stephen V., Earp, H. Shelton, Graves, Lee M., Johnson, Gary L.

“…Kinase inhibitors have limited success in cancer treatment because tumors circumvent their action. Using a quantitative proteomics approach, we assessed kinome…”
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RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma by Whittle, Martin C., Izeradjene, Kamel, Rani, P. Geetha, Feng, Libing, Carlson, Markus A., DelGiorno, Kathleen E., Wood, Laura D., Goggins, Michael, Hruban, Ralph H., Chang, Amy E., Calses, Philamer, Thorsen, Shelley M., Hingorani, Sunil R.

“…For the majority of patients with pancreas cancer, the high metastatic proclivity is life limiting. Some patients, however, present with and succumb to locally…”
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Quantum correlations between light and the kilogram-mass mirrors of LIGO by Yu, Haocun, McCuller, L., Tse, M., Kijbunchoo, N., Barsotti, L., Mavalvala, N.

“…The measurement of minuscule forces and displacements with ever greater precision is inhibited by the Heisenberg uncertainty principle, which imposes a limit…”
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The dynamic nature of the kinome by Graves, Lee M, Duncan, James S, Whittle, Martin C, Johnson, Gary L

“…Recent advances in proteomics have facilitated the analysis of the kinome 'en masse'. What these studies have revealed is a surprisingly dynamic network of…”
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Frequency-Dependent Squeezing for Advanced LIGO by McCuller, L., Whittle, C., Ganapathy, D., Komori, K., Tse, M., Fernandez-Galiana, A., Barsotti, L., Fritschel, P., MacInnis, M., Matichard, F., Mason, K., Mavalvala, N., Mittleman, R., Yu, Haocun, Zucker, M. E., Evans, M.

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Runx3 and Cell Fate Decisions in Pancreas Cancer by Whittle, Martin C, Hingorani, Sunil R

“…The RUNX family transcription factors are critical regulators of development and frequently dysregulated in cancer. RUNX3, the least well characterized of the…”
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Photophysics of Diimine Platinum(II) Bis-Acetylide Complexes by Whittle, C. Ed, Weinstein, Julia A, George, Michael W, Schanze, Kirk S

“…A comprehensive photophysical investigation has been carried out on a series of eight complexes of the type (diimine)Pt(−C⋮C−Ar)2, where diimine is a series of…”
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Revaccination with Live Attenuated Vaccines Confer Additional Beneficial Nonspecific Effects on Overall Survival: A Review by Benn, Christine S., Fisker, Ane B., Whittle, Hilton C., Aaby, Peter

“…Live vaccines against measles (MV), tuberculosis (BCG), polio (OPV) and smallpox reduce mortality more than explained by target-disease prevention. The…”
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Contradictory mortality results in early 2-dose measles vaccine trials: interactions with oral polio vaccine may explain differences by Nielsen, Sebastian, Fisker, Ane B., Sie, Ali, Müller, Olaf, Nebie, Eric, Becher, Heiko, van der Klis, Fiona, Biering-Sørensen, Sofie, Byberg, Stine, Thysen, Sanne M., da Silva, Isaquel, Rodrigues, Amabelia, Martins, Cesario, Whittle, Hilton C., Aaby, Peter, Benn, Christine S.

“…•A 2-dose vs 1-dose measles vaccine (MV) schedule was beneficial in the first RCT.•However, in two later RCTs mortality tended to be higher in the 2-dose…”
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Early virological and immunological events in asymptomatic Epstein-Barr virus infection in African children by Jayasooriya, Shamanthi, de Silva, Thushan I, Njie-jobe, Jainaba, Sanyang, Chilel, Leese, Alison M, Bell, Andrew I, McAulay, Karen A, Yanchun, Peng, Long, Heather M, Dong, Tao, Whittle, Hilton C, Rickinson, Alan B, Rowland-Jones, Sarah L, Hislop, Andrew D, Flanagan, Katie L

“…Epstein-Barr virus (EBV) infection often occurs in early childhood and is asymptomatic. However, if delayed until adolescence, primary infection may manifest…”
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Dynamics of transcriptome evolution in the model eukaryote Neurospora by Whittle, C. A, Sun, Y, Johannesson, H

“…Mounting evidence indicates that changes in the transcriptome contribute significantly to the phenotypic differentiation of closely related species…”
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KIR content genotypes associate with carriage of hepatitis B surface antigen, e antigen and HBV viral load in Gambians by Yindom, Louis-Marie, Mendy, Maimuna, Bodimeade, Christopher, Chambion, Caroline, Aka, Peter, Whittle, Hilton C, Rowland-Jones, Sarah L, Walton, Robert

“…Hepatocellular carcinoma (HCC) causes over 800,000 deaths worldwide annually, mainly in low income countries, and incidence is rising rapidly in the developed…”
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Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis by Ceesay, Serign J, MSc, Casals-Pascual, Climent, DPhil, Erskine, Jamie, MB, Anya, Samuel E, MRCOG, Duah, Nancy O, MSc, Fulford, Anthony JC, PhD, Sesay, Sanie SS, MB, Abubakar, Ismaela, BSc, Dunyo, Samuel, PhD, Sey, Omar, MSc, Palmer, Ayo, MRCP, Fofana, Malang, MSc, Corrah, Tumani, Prof, Bojang, Kalifa A, MRCP, Whittle, Hilton C, Prof, Greenwood, Brian M, Prof, Conway, David J, Dr

“…Summary Background Malaria is a major cause of morbidity and mortality in Africa. International effort and funding for control has been stepped up, with…”
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Long-Term Protection against Carriage of Hepatitis B Virus after Infant Vaccination by Sande, M. A. B. van der, Waight, P., Mendy, M., Rayco-Solon, P., Hutt, P., Fulford, T., Doherty, C., McConkey, S. J., Jeffries, D., Hall, A. J., Whittle, H. C.

“…BackgroundCarriage of hepatitis B virus (HBV) is a major risk factor for liver cirrhosis and hepatocellular carcinoma. Infant vaccination has been effective in…”
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Polyfunctional T cell responses are a hallmark of HIV‐2 infection by Duvall, Melody G., Precopio, Melissa L., Ambrozak, David A., Jaye, Assan, McMichael, Andrew J., Whittle, Hilton C., Roederer, Mario, Rowland‐Jones, Sarah L., Koup, Richard A.

“…HIV‐2 is distinguished clinically and immunologically from HIV‐1 infection by delayed disease progression and maintenance of HIV‐specific CD4+ T cell help in…”
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“Truffle sign”. A suspicious malignant pattern of lymphadenopathies in children observed on ultrasound. Preliminary study by Pérez-Marrero, L., Norambuena, M. F., Whittle, C., Fuentealba, I. M., Spralja, B.

“…Background The differential diagnosis of lymphadenopathies in children including benign and malignant conditions is often difficult to identify by ultrasound…”
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Clinical Outcomes by Race and Ethnicity in the Systolic Blood Pressure Intervention Trial (SPRINT): A Randomized Clinical Trial by Still, Carolyn H, Rodriguez, Carlos J, Wright, Jackson T, Craven, Timothy E, Bress, Adam P, Chertow, Glenn M, Whelton, Paul K, Whittle, Jeffrey C, Freedman, Barry I, Johnson, Karen C, Foy, Capri G, He, Jiang, Kostis, John B, Lash, James P, Pedley, Carolyn F, Pisoni, Roberto, Powell, James R, Wall, Barry M

“…Abstract BACKGROUND The Systolic Blood Pressure Intervention Trial (SPRINT) showed that targeting a systolic blood pressure (SBP) of ≤ 120 mm Hg (intensive…”
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Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1? by Rowland-Jones, Sarah L, Whittle, Hilton C

“…Most people infected with human immunodeficiency virus 2 (HIV-2) do not progress to disease, even though the minority who do cannot be distinguished clinically…”
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Genome-wide selection on codon usage at the population level in the fungal model organism Neurospora crassa by Whittle, C A, Sun, Y, Johannesson, H

“…Many organisms exhibit biased codon usage in their genome, including the fungal model organism Neurospora crassa. The preferential use of subset of synonymous…”
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