Search Results - "Whittingham‐Dowd, Jayde"

Altered medial prefrontal cortex and dorsal raphé activity predict genotype and correlate with abnormal learning behavior in a mouse model of autism‐associated 2p16.3 deletion by Hughes, Rebecca B., Whittingham‐Dowd, Jayde, Clapcote, Steven J., Broughton, Susan J., Dawson, Neil

“…2p16.3 deletion, involving NEUREXIN1 (NRXN1) heterozygous deletion, substantially increases the risk of developing autism and other neurodevelopmental…”
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Listeria monocytogenes alters mast cell phenotype, mediator and osteopontin secretion in a listeriolysin-dependent manner by Jobbings, Catherine E, Sandig, Hilary, Whittingham-Dowd, Jayde K, Roberts, Ian S, Bulfone-Paus, Silvia

“…Whilst mast cells participate in the immune defence against the intracellular bacterium Listeria monocytogenes, there is conflicting evidence regarding the…”
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IL‐33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation by Sandig, Hilary, Jobbings, Catherine E., Roldan, Nestor Gonzalez, Whittingham‐Dowd, Jayde K., Orinska, Zane, Takeuchi, Osamu, Akira, Shizuo, Bulfone‐Paus, Silvia

“…Mast cells are important cellular constituents of epithelial–mesenchymal interactions, densely located at sites of microbial entry into the host where they are…”
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Intestinal epithelial suppressor of cytokine signaling 3 (SOCS3) impacts on mucosal homeostasis in a model of chronic inflammation by Shaw, Elisabeth J., Smith, Emily E., Whittingham‐Dowd, Jayde, Hodges, Matthew D., Else, Kathryn J., Rigby, Rachael J.

“…Introduction Suppressor of cytokine signaling 3 (SOCS3) is a tumour suppressor, limiting intestinal epithelial cell (IEC) proliferation in acute inflammation,…”
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ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites by Campbell, Laura, Hepworth, Matthew R, Whittingham-Dowd, Jayde, Thompson, Seona, Bancroft, Allison J, Hayes, Kelly S, Shaw, Tovah N, Dickey, Burton F, Flamar, Anne-Laure, Artis, David, Schwartz, David A, Evans, Christopher M, Roberts, Ian S, Thornton, David J, Grencis, Richard K

“…Host immunity to parasitic nematodes requires the generation of a robust type 2 cytokine response, characterized by the production of interleukin 13 (IL-13),…”
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Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (AI-LAMP) for Rapid Detection of SARS-CoV-2 by Rohaim, Mohammed A., Clayton, Emily, Sahin, Irem, Vilela, Julianne, Khalifa, Manar E., Al-Natour, Mohammad Q., Bayoumi, Mahmoud, Poirier, Aurore C., Branavan, Manoharanehru, Tharmakulasingam, Mukunthan, Chaudhry, Nouman S., Sodi, Ravinder, Brown, Amy, Burkhart, Peter, Hacking, Wendy, Botham, Judy, Boyce, Joe, Wilkinson, Hayley, Williams, Craig, Whittingham-Dowd, Jayde, Shaw, Elisabeth, Hodges, Matt, Butler, Lisa, Bates, Michelle D., La Ragione, Roberto, Balachandran, Wamadeva, Fernando, Anil, Munir, Muhammad

“…Until vaccines and effective therapeutics become available, the practical solution to transit safely out of the current coronavirus disease 19 (CoVID-19)…”
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Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2 by Park, Jun-Gyu, Oladunni, Fatai S., Rohaim, Mohammed A., Whittingham-Dowd, Jayde, Tollitt, James, Hodges, Matthew D.J., Fathallah, Nadin, Assas, Muhsref Bakri, Alhazmi, Wafaa, Almilaibary, Abdullah, Iqbal, Munir, Chang, Pengxiang, Escalona, Renee, Shivanna, Vinay, Torrelles, Jordi B., Worthington, John J., Jackson-Jones, Lucy H., Martinez-Sobrido, Luis, Munir, Muhammad

“…Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome…”
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The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential by Burley, Simon D, Whittingham-Dowd, Jayde, Allen, Jeremy, Grosset, Jean-Francois, Onambele-Pearson, Gladys L

“…Substantial gains in muscle strength and hypertrophy are clearly associated with the routine performance of resistance training. What is less evident is the…”
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PPARγ as a molecular target of EPA anti-inflammatory activity during TNF-α-impaired skeletal muscle cell differentiation by Magee, Peter, Pearson, Stephen, Whittingham-Dowd, Jayde, Allen, Jeremy

“…Activated skeletal muscle satellite cells facilitate muscle repair or growth through proliferation, differentiation and fusion into new or existing myotubes…”
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Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion by B Hughes, Rebecca, Whittingham-Dowd, Jayde, Simmons, Rachel E, Clapcote, Steven J, Broughton, Susan J, Dawson, Neil

“…Abstract 2p16.3 deletions, involving heterozygous NEUREXIN1 (NRXN1) deletion, dramatically increase the risk of developing neurodevelopmental disorders,…”
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F37. CACNA1C HYPOFUNCTION IN KETAMINE-ACTIVATED BRAIN NETWORKS IMPAIRS MEMORY CONSOLIDATION AND FUNCTIONAL BRAIN NETWORK CONNECTIVITY by Hughes, Rebecca, Willi, Cosima, Whittingham-Dowd, Jayde, Broughton, Susan, Bristow, Greg, Dawson, Neil

“…Abstract Background The CACNA1C gene, encoding the pore forming subunit of the calcium channel Cav1.2, is an established risk factor for a variety of…”
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F40. NEUREXIN-1α (NRNX1α) HYPOFUNCTION INDUCES SCHIZOPHRENIA-RELEVANT DEFICITS IN CEREBRAL METABOLISM, COGNITIVE PROCESSING SPEED AND COGNITIVE FLEXIBILITY by Hughes, Rebecca, Whittingham-Dowd, Jayde, Bristow, Greg, Clapcote, Stephen, Broughton, Susan, Dawson, Neil

“…Abstract Background Heterozygous deletions in NEUREXIN-1 (NRXN1) substantially increase the risk of developing schizophrenia (SZ) (Rujescu et al., 2009. Hum…”
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Tumour necrosis factor‐related weak inducer of apoptosis (TWEAK)‐induced skeletal muscle damage is attenuated by the omega‐3 polyunsaturated fatty acid (PUFA) docosohexaenoic acid (DHA) by Whittingham‐Dowd, Jayde Kathleen, Allen, Jeremy Thomas, Pearson, Steve

“…TWEAK is a member of the tumor necrosis factor (TNF) superfamily implicated in several inflammatory pathologies including skeletal muscle wasting. Previously…”
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Investigating the Use of Omega Three Fish Oils as Protective Agents Against Cytokine-induced Skeletal Muscle Damage by Whittingham-Dowd, Jayde Kathleen

“…IntroductionMuscle injury and disease impacts on the lives of adults and children, contributing to severe morbidity and increased mortality e.g. Muscular…”
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