Search Results - "Whittal, Randy M"

Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction by Prasad, Manoj, Kaur, Jasmeet, Pawlak, Kevin J., Bose, Mahuya, Whittal, Randy M., Bose, Himangshu S.

“…Steroid hormones are essential for carbohydrate metabolism, stress management, and reproduction and are synthesized from cholesterol in mitochondria of adrenal…”
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Interferences and contaminants encountered in modern mass spectrometry by Keller, Bernd O., Sui, Jie, Young, Alex B., Whittal, Randy M.

“…With the invention of electrospray ionization and matrix-assisted laser desorption/ionization, scientists employing modern mass spectrometry naturally face new…”
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Purification and characterization of antifungal lipopeptide produced by Bacillus velezensis isolated from raw honey by Xiong, Zirui Ray, Cobo, Mario, Whittal, Randy M, Snyder, Abigail B, Worobo, Randy W

“…Raw honey contains a diverse microbiota originating from honeybees, plants, and soil. Some gram-positive bacteria isolated from raw honey are known for their…”
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Thuricin CD, a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile by Rea, Mary C, Sit, Clarissa S, Clayton, Evelyn, O'Connor, Paula M, Whittal, Randy M, Zheng, Jing, Vederas, John C, Ross, R. Paul, Hill, Colin

“…The last decade has seen numerous outbreaks of Clostridium difficile-associated disease (CDAD), which presented significant challenges for healthcare…”
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Research into the Bioengineering of a Novel α-Conotoxin from the Milked Venom of Conus obscurus by Wiere, Sean, Sugai, Christopher, Espiritu, Michael J, Aurelio, Vincent P, Reyes, Chloe D, Yuzon, Nicole, Whittal, Randy M, Tytgat, Jan, Peigneur, Steve, Bingham, Jon-Paul

“…The marine cone snail produces one of the fastest prey strikes in the animal kingdom. It injects highly efficacious venom, often causing prey paralysis and…”
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Tom40 in cholesterol transport by Bose, Himangshu S., Bose, Mahuya, Whittal, Randy M.

“…Cholesterol initiates steroid metabolism in adrenal and gonadal mitochondria, which is essential for all mammalian survival. During stress an increased…”
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Bioactive Contaminants Leach from Disposable Laboratory Plasticware by McDonald, G. Reid, Hudson, Alan L, Dunn, Susan M.J, You, Haitao, Baker, Glen B, Whittal, Randy M, Martin, Jonathan W, Jha, Amitabh, Edmondson, Dale E, Holt, Andrew

“…Disposable plasticware such as test tubes, pipette tips, and multiwell assay or culture plates are used routinely in most biological research laboratories…”
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Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein by Bose, Mahuya, Whittal, Randy M., Miller, Walter L., Bose, Himangshu S.

“…The steroidogenic acute regulatory protein (StAR) is required for adrenal and gonadal steroidogenesis and for male sexual differentiation. StAR acts on the…”
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Isolation and Characterization of Carnocyclin A, a Novel Circular Bacteriocin Produced by Carnobacterium maltaromaticum UAL307 by Martin-Visscher, Leah A, van Belkum, Marco J, Garneau-Tsodikova, Sylvie, Whittal, Randy M, Zheng, Jing, McMullen, Lynn M, Vederas, John C

“…Carnobacterium maltaromaticum UAL307, isolated from fresh pork, exhibits potent activity against a number of gram-positive organisms, including numerous…”
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Mitochondrial metabolic regulation by GRP78 by Prasad, Manoj, Pawlak, Kevin J, Burak, William E, Perry, Elizabeth E, Marshall, Brendan, Whittal, Randy M, Bose, Himangshu S

“…Steroids, essential for mammalian survival, are initiated by cholesterol transport by steroidogenic acute regulatory protein (StAR). Appropriate protein…”
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Phenylbutazone Oxidation via Cu,Zn-SOD Peroxidase Activity: An EPR Study by Aljuhani, Naif, Whittal, Randy M, Khan, Saifur R, Siraki, Arno G

“…We investigated the effect of Cu,Zn-superoxide dismutase (Cu,Zn-SOD)-peroxidase activity on the oxidation of the nonsteroidal anti-inflammatory drug…”
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Electron Transport Chain Complex II Regulates Steroid Metabolism by Bose, Himangshu S., Marshall, Brendan, Debnath, Dilip K., Perry, Elizabeth W., Whittal, Randy M.

“…The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid…”
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Identification of an N-Terminal Formylated, Two-Peptide Bacteriocin from Enterococcus faecalis 710C by Liu, Xiaoji, Vederas, John C, Whittal, Randy M, Zheng, Jing, Stiles, Michael E, Carlson, Denise, Franz, Charles M. A. P, McMullen, Lynn M, van Belkum, Marco J

“…Enterococcus faecalis 710C, isolated from beef product, has a broad antimicrobial activity spectrum against foodborne pathogens. Two bacteriocins, enterocin 7A…”
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Naphthenic acids and other acid-extractables in water samples from Alberta: What is being measured? by Grewer, David M., Young, Rozlyn F., Whittal, Randy M., Fedorak, Phillip M.

“…There is increasing international interest in naphthenic acids (NAs, classical formula C nH 2n + Z O 2) found in the oil sands from Alberta, Canada and in…”
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Two-Layer Sample Preparation:  A Method for MALDI-MS Analysis of Complex Peptide and Protein Mixtures by Dai, Yuqin, Whittal, Randy M, Li, Liang

“…The analytical performance of matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for direct analysis of peptide and protein mixtures is…”
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The Active Form of the Steroidogenic Acute Regulatory Protein, StAR, Appears to Be a Molten Globule by Bose, Himangshu S., Whittal, Randy M., Baldwin, Michael A., Miller, Walter L.

“…The steroidogenic acute regulatory protein (StAR) increases the movement of cholesterol from the outer to the inner membrane of adrenal and gonadal…”
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Extracellular Proteomes of Arabidopsis Thaliana and Brassica Napus Roots: Analysis and Comparison by MudPIT and LC-MS/MS by Basu, U, Francis, J.L, Whittal, R.M, Stephens, J.L, Wang, Y, Zaiane, O.R, Goebel, R, Muench, D.G, Good, A.G, Taylor, G.J

“…An important principle of the functional organization of plant cells is the targeting of proteins to specific subcellular locations. The physical location of…”
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High-Resolution Matrix-Assisted Laser Desorption/Ionization in a Linear Time-of-Flight Mass Spectrometer by Whittal, Randy M, Li, Liang

“…A time-lag focusing method is developed for the improvement of mass resolution in a linear time-of-flight mass spectrometer for matrix-assisted laser…”
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A Novel Mitochondrial Complex of Aldosterone Synthase, Steroidogenic Acute Regulatory Protein, and Tom22 Synthesizes Aldosterone in the Rat Heart by Bose, Himangshu S, Whittal, Randy M, Marshall, Brendan, Rajapaksha, Maheshinie, Wang, Ning Ping, Bose, Madhuchanda, Perry, Elizabeth W, Zhao, Zhi-Qing, Miller, Walter L

“…Aldosterone, which regulates renal salt retention, is synthesized in adrenocortical mitochondria in response to angiotensin II. Excess aldosterone causes…”
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Inner Mitochondrial Translocase Tim50 Is Central in Adrenal and Testicular Steroid Synthesis by Bose, Himangshu S., Gebrail, Fadi, Marshall, Brendan, Perry, Elizabeth W., Whittal, Randy M.

“…Adrenal and gonadal mitochondrial metabolic activity requires electrons from cofactors, cholesterol, and a substrate for rapid steroid synthesis, an essential…”
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