Search Results - "Whittaker, Matthew K"
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Targeting the WASF3 complex to suppress metastasis
Published in Pharmacological research (01-08-2022)“…Wiskott-Aldrich syndrome protein family members (WASF) regulate the dynamics of the actin cytoskeleton, which plays an instrumental role in cancer metastasis…”
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Targeted Degradation of Protein Kinase A via a Stapled Peptide PROTAC
Published in ACS chemical biology (20-09-2024)“…Proteolysis-targeting chimeras (PROTACs) are bifunctional molecules that bind and recruit an E3 ubiquitin ligase to a targeted protein of interest, often…”
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In Silico Optimized Stapled Peptides Targeting WASF3 in Breast Cancer
Published in ACS medicinal chemistry letters (14-04-2022)“…Wiskott-Aldrich Syndrome Protein Family (WASF) members regulate actin cytoskeletal dynamics, and WASF3 is directly associated with breast cancer metastasis and…”
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Journal Article