Search Results - "Whitney, Christopher P"

ASCL1 represses a SOX9 + neural crest stem-like state in small cell lung cancer by Olsen, Rachelle R, Ireland, Abbie S, Kastner, David W, Groves, Sarah M, Spainhower, Kyle B, Pozo, Karine, Kelenis, Demetra P, Whitney, Christopher P, Guthrie, Matthew R, Wait, Sarah J, Soltero, Danny, Witt, Benjamin L, Quaranta, Vito, Johnson, Jane E, Oliver, Trudy G

“…ASCL1 is a neuroendocrine lineage-specific oncogenic driver of small cell lung cancer (SCLC), highly expressed in a significant fraction of tumors. However,…”
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MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer by Dammert, Marcel A., Brägelmann, Johannes, Olsen, Rachelle R., Böhm, Stefanie, Monhasery, Niloufar, Whitney, Christopher P., Chalishazar, Milind D., Tumbrink, Hannah L., Guthrie, Matthew R., Klein, Sebastian, Ireland, Abbie S., Ryan, Jeremy, Schmitt, Anna, Marx, Annika, Ozretić, Luka, Castiglione, Roberta, Lorenz, Carina, Jachimowicz, Ron D., Wolf, Elmar, Thomas, Roman K., Poirier, John T., Büttner, Reinhard, Sen, Triparna, Byers, Lauren A., Reinhardt, H. Christian, Letai, Anthony, Oliver, Trudy G., Sos, Martin L.

“…MYC paralogs are frequently activated in small cell lung cancer (SCLC) but represent poor drug targets. Thus, a detailed mapping of MYC -paralog-specific…”
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