Search Results - "Whitmore, Theodore E"
-
1
Cloning and Characterization of Human Protease-Activated Receptor 4
Published in Proceedings of the National Academy of Sciences - PNAS (09-06-1998)“…Protease-activated receptors 1-3 (PAR1, PAR2, and PAR3) are members of a unique G protein-coupled receptor family. They are characterized by a tethered peptide…”
Get full text
Journal Article -
2
IL-28, IL-29 and their class II cytokine receptor IL-28R
Published in Nature immunology (01-01-2003)“…Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three…”
Get full text
Journal Article -
3
Expression of IL-17B in neurons and evaluation of its possible role in the chromosome 5q-linked form of Charcot–Marie–Tooth disease
Published in Neuromuscular disorders : NMD (01-02-2002)“…IL-17B is a recently identified homolog of IL-17. Northern analysis revealed that IL-17B mRNA is expressed at very high levels in spinal cord and at much lower…”
Get full text
Journal Article -
4
Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer
Published in Journal of proteome research (04-05-2012)“…In an attempt to identify prostate cancer biomarkers with greater diagnostic and prognostic capabilities, we have developed an integrative proteomic discovery…”
Get full text
Journal Article -
5
Interleukin 20: Discovery, Receptor Identification, and Role in Epidermal Function
Published in Cell (12-01-2001)“…A structural, profile-based algorithm was used to identify interleukin 20 (IL-20), a novel IL-10 homolog. Chromosomal localization of IL-20 led to the…”
Get full text
Journal Article -
6
MT-III, a Brain-Specific Member of the Metallothionein Gene Family
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-1992)“…A third member of the metallothionein (MT) gene family, designated MT-III, was cloned by virtue of its homology to a human protein that was shown previously to…”
Get full text
Journal Article -
7
Identification of INSL5, a New Member of the Insulin Superfamily
Published in Genomics (San Diego, Calif.) (15-08-1999)“…A new member of the insulin gene superfamily (INSL5) was identified by searching EST databases for the presence of the conserved insulin B-chain cysteine…”
Get full text
Journal Article -
8
Identification of a Mammalian Angiopoietin-Related Protein Expressed Specifically in Liver
Published in Genomics (San Diego, Calif.) (15-12-1999)“…Based on searches of EST databases for signal sequences and amphipathic helices, we have identified and cloned an angiopoietin-like gene, ANGPTL3. Multiple…”
Get full text
Journal Article -
9
Cloning and Characterization of a Novel Class I Cytokine Receptor
Published in Biochemical and biophysical research communications (08-05-1998)“…The human gp130 cDNA sequence was used as a query to search an expressed sequence tag database (dbEST) to identify cDNA sequences with similarity to the…”
Get full text
Journal Article -
10
Identification of INSL6, a New Member of the Insulin Family That Is Expressed in the Testis of the Human and Rat1
Published in Biology of reproduction (01-06-2000)“…A new member of the insulin gene family (INSL6) was identified from an Expressed Sequence Tag database through a search for proteins containing the insulin…”
Get full text
Journal Article -
11
A Soluble Class II Cytokine Receptor, IL-22RA2, is a Naturally Occurring IL-22 Antagonist
Published in Proceedings of the National Academy of Sciences - PNAS (14-08-2001)“…IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2-4. IL-22 is produced by T cells and…”
Get full text
Journal Article -
12
Identification of INSL6, a New Member of the Insulin Family That Is Expressed in the Testis of the Human and Rat
Published in Biology of reproduction (01-06-2000)“…A new member of the insulin gene family ( INSL6 ) was identified from an Expressed Sequence Tag database through a search for proteins containing the insulin…”
Get full text
Journal Article -
13
Molecular cloning, chromosome mapping and characterization of UBQLN3 a testis-specific gene that contains an ubiquitin-like domain
Published in Gene (16-05-2000)“…The sequence of the ubiquitin protein is highly conserved between species and has facilitated the cloning of numerous ubiquitin-like proteins. In the present…”
Get full text
Journal Article -
14
Cloning and characterization of an abundant subtype of the human calcitonin receptor
Published in Molecular pharmacology (01-08-1994)“…We have cloned and characterized a second form of the human calcitonin receptor from T47D cells. It resembles the clone described by Gorn et al. [J. Clin…”
Get more information
Journal Article -
15
Human Thrombopoietin: Gene Structure, cDNA Sequence, Expression, and Chromosomal Localization
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-1994)“…Thrombopoietin (TPO), a lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from committed progenitor cells, is believed to…”
Get full text
Journal Article -
16
Molecular cloning, chromosome mapping and characterization of a testis-specific cystatin-like cDNA, cystatin T
Published in Gene (07-03-2000)“…The cystatin superfamily of cysteine proteinase inhibitors consists of three major families. In the present study, we report the cloning of the cDNA for mouse…”
Get full text
Journal Article -
17
The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization
Published in Gene (25-03-1994)“…Characterization of the human glucagon-receptor-encoding gene (GGR) should provide a greater understanding of blood glucose regulation and may reveal a genetic…”
Get more information
Journal Article -
18
-
19
Purification and molecular cloning of human apolipoprotein F
Published in Biochemical and biophysical research communications (15-09-1994)“…In our effort to study proteins that are involved in high density lipoprotein metabolism, we have identified apolipoprotein F and isolated a full length cDNA…”
Get more information
Journal Article -
20
Chromosomal deletion 4p15.32----p14 in a Treacher Collins syndrome patient: exclusion of the disease locus from and mapping of anonymous DNA sequences to this region
Published in Genomics (San Diego, Calif.) (01-09-1991)“…Treacher Collins syndrome is an autosomal dominant condition of bilateral craniofacial abnormalities of structures derived from the first and second branchial…”
Get more information
Journal Article