Search Results - "Whitmore, Leanna A"

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells by Vicente-Manzanares, Miguel, Newell-Litwa, Karen, Bachir, Alexia I, Whitmore, Leanna A, Horwitz, Alan Rick

“…Migratory front-back polarity emerges from the cooperative effect of myosin IIA (MIIA) and IIB (MIIB) on adhesive signaling. We demonstrate here that, during…”
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α-Actinin-2 mediates spine morphology and assembly of the post-synaptic density in hippocampal neurons by Hodges, Jennifer L, Vilchez, Samuel Martin, Asmussen, Hannelore, Whitmore, Leanna A, Horwitz, Alan Rick

“…Dendritic spines are micron-sized protrusions that constitute the primary post-synaptic sites of excitatory neurotransmission in the brain. Spines mature from…”
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A regulatory motif in nonmuscle myosin II-B regulates its role in migratory front-back polarity by Juanes-Garcia, Alba, Chapman, Jessica R, Aguilar-Cuenca, Rocio, Delgado-Arevalo, Cristina, Hodges, Jennifer, Whitmore, Leanna A, Shabanowitz, Jeffrey, Hunt, Donald F, Horwitz, Alan Rick, Vicente-Manzanares, Miguel

“…In this study, we show that the role of nonmuscle myosin II (NMII)-B in front-back migratory cell polarity is controlled by a short stretch of amino acids…”
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Actin and α-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner by Choi, Colin K, Horwitz, Alan Rick, Zareno, Jessica, Vicente-Manzanares, Miguel, Whitmore, Leanna A, Mogilner, Alex

“…Adhesion assembly is needed for cell migration. Horwitz and colleagues report that new adhesions assemble in the lamellipodium in a manner that is independent…”
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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly by Webb, Donna J, Donais, Karen, Whitmore, Leanna A, Thomas, Sheila M, Turner, Christopher E, Parsons, J. Thomas, Horwitz, Alan F

“…Cell migration is a complex, highly regulated process that involves the continuous formation and disassembly of adhesions (adhesion turnover). Adhesion…”
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Actinin-2 Mediates Spine Morphology and Assembly of the Post-Synaptic Density in Hippocampal Neurons by Hodges, Jennifer L, Vilchez, Samuel Martin, Asmussen, Hannelore, Whitmore, Leanna A, Horwitz, Alan Rick

“…Dendritic spines are micron-sized protrusions that constitute the primary post-synaptic sites of excitatory neurotransmission in the brain. Spines mature from…”
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Actin and [alpha]-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner by Choi, Colin K, Vicente-manzanares, Miguel, Zareno, Jessica, Whitmore, Leanna A, Mogilner, Alex, Horwitz, Alan Rick

“…Using two-colour imaging and high resolution TIRF microscopy, we investigated the assembly and maturation of nascent adhesions in migrating cells. We show that…”
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