Search Results - "Whitmore, James"
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Lower Baseline Prostate-specific Antigen Is Associated With a Greater Overall Survival Benefit From Sipuleucel-T in the Immunotherapy for Prostate Adenocarcinoma Treatment (IMPACT) Trial
Published in Urology (Ridgewood, N.J.) (01-06-2013)“…Objective To explore the prognostic and predictive value of baseline variables in 512 patients with metastatic castration-resistant prostate cancer from the…”
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Toxicity and Efficacy Probability Interval Design for Phase I Adoptive Cell Therapy Dose-Finding Clinical Trials
Published in Clinical cancer research (01-01-2017)“…Recent trials of adoptive cell therapy (ACT), such as the chimeric antigen receptor (CAR) T-cell therapy, have demonstrated promising therapeutic effects for…”
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Sipuleucel-T immune parameters correlate with survival: an analysis of the randomized phase 3 clinical trials in men with castration-resistant prostate cancer
Published in Cancer Immunology, Immunotherapy (01-01-2013)“…Purpose Sipuleucel-T, the first FDA-approved autologous cellular immunotherapy for treatment of advanced prostate cancer, is manufactured by activating…”
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Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome
Published in Clinical cancer research (15-08-2015)“…Antitumor activity of cancer immunotherapies may elicit immune responses to nontargeted (secondary) tumor antigens, or antigen spread. We evaluated humoral…”
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T-cell malignancies with anti-CD19 chimeric antigen receptor T-cell therapy
Published in Blood advances (13-08-2024)Get full text
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6
Anemia and its relationship to clinical outcome in heart failure
Published in Circulation (New York, N.Y.) (13-07-2004)“…Anemia is often observed in patients with chronic heart failure (CHF), but its implications for patient outcomes are not well understood. The goal of this…”
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Integrated safety data from 4 randomized, double-blind, controlled trials of autologous cellular immunotherapy with sipuleucel-T in patients with prostate cancer
Published in The Journal of urology (01-09-2011)“…We describe the safety of sipuleucel-T using an integrated analysis of 4 randomized, controlled studies in patients with prostate cancer. Adverse events,…”
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Etanercept treatment in adults with established rheumatoid arthritis: 7 years of clinical experience
Published in Journal of rheumatology (01-05-2006)“…OBJECTIVE: To evaluate safety and efficacy of longterm etanercept treatment in patients with disease modifying antirheumatic drug (DMARD) refractory rheumatoid…”
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Survival Outcomes of Sipuleucel-T Phase III Studies: Impact of Control-Arm Cross-Over to Salvage Immunotherapy
Published in Cancer immunology research (01-09-2015)“…Sipuleucel-T is an autologous cellular immunotherapy for asymptomatic/minimally symptomatic metastatic castrate-resistant prostate cancer (CRPC). After disease…”
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10
Share your views on key concerns
Published in Veterinary record (03-02-2024)Get full text
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Active allyship: helping everyone to thrive in the workplace
Published in Veterinary record (03-02-2024)“…As LGBT+ History Month kicks off, BVLGBT+ president James Whitmore explains how the whole profession can help foster inclusive workplaces through active…”
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Re: interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer
Published in JNCI : Journal of the National Cancer Institute (18-07-2012)Get full text
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Pneumococcal vaccine response in psoriatic arthritis patients during treatment with etanercept
Published in Journal of rheumatology (01-07-2004)“…OBJECTIVE: Therapeutics used to treat inflammatory diseases, including psoriatic arthritis (PsA), may potentially interfere with normal immune system function…”
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Longterm safety, efficacy, and radiographic outcome with etanercept treatment in patients with early rheumatoid arthritis
Published in Journal of rheumatology (01-07-2005)“…OBJECTIVE: To evaluate safety, efficacy, and radiographic progression in patients with early rheumatoid arthritis (RA) undergoing longterm treatment with…”
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15
Pride is a movement, not just a moment
Published in Veterinary record (08-07-2023)“…June saw the nationwide celebration of Pride Month. BVLGBT+ president James Whitmore reflects on the origins of Pride events and the reason they're still…”
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Recognising workplaces prioritising team wellbeing
Published in Veterinary record (08-07-2023)Get full text
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Efficacy of soluble IL-4 receptor for the treatment of adults with asthma
Published in Journal of allergy and clinical immunology (01-06-2001)“…Background: IL-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, increased expression of vascular cell…”
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Celebrating LGBT+ History Month 2023
Published in Veterinary record (01-02-2023)“…As LGBT+ History Month kicks off, BVLGBT+ president James Whitmore introduces the society's role model campaign…”
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Quality of Life After Sipuleucel-T Therapy: Results From a Randomized, Double-blind Study in Patients With Androgen-dependent Prostate Cancer
Published in Urology (Ridgewood, N.J.) (01-08-2013)“…Objective To collect and analyze quality-of-life (QOL) data from PROvenge Treatment and Early Cancer Treatment trial (PROTECT, NCT00779402 ), a phase III,…”
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Interleukin-4 receptor in moderate atopic asthma: A phase I/II randomized, placebo-controlled trial
Published in American journal of respiratory and critical care medicine (01-12-1999)“…Interleukin-4 mediates important proinflammatory functions in asthma, including induction of the IgE isotype switch, expression of VCAM-1 on endothelium, mucin…”
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