Search Results - "Whitlock, Andrew"

Increased intraocular pressure in mice treated with dexamethasone by Whitlock, N Andrew, McKnight, Beth, Corcoran, Katie N, Rodriguez, Lawrence A, Rice, Dennis S

“…Glucocorticoids are potent modulators of the immune system and are useful in treating systemic and ocular diseases, but they can increase intraocular pressure…”
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Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma by Harrison, Bryce A, Whitlock, N. Andrew, Voronkov, Michael V, Almstead, Zheng Y, Gu, Kun-jian, Mabon, Ross, Gardyan, Michael, Hamman, Brian D, Allen, Jason, Gopinathan, Suma, McKnight, Beth, Crist, Mike, Zhang, Yulian, Liu, Ying, Courtney, Lawrence F, Key, Billie, Zhou, Julia, Patel, Nita, Yates, Phil W, Liu, Qingyun, Wilson, Alan G. E, Kimball, S. David, Crosson, Craig E, Rice, Dennis S, Rawlins, David B

“…The discovery of a pyrrolopyrimidine class of LIM-kinase 2 (LIMK2) inhibitors is reported. These LIMK2 inhibitors show good potency in enzymatic and cellular…”
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Discovery and Development of LX7101, a Dual LIM-Kinase and ROCK Inhibitor for the Treatment of Glaucoma by Harrison, Bryce A, Almstead, Zheng Y, Burgoon, Hugh, Gardyan, Michael, Goodwin, Nicole C, Healy, Jason, Liu, Ying, Mabon, Ross, Marinelli, Brett, Samala, Lakshman, Zhang, Yulian, Stouch, Terry R, Whitlock, N. Andrew, Gopinathan, Suma, McKnight, Beth, Wang, Shuli, Patel, Nita, Wilson, Alan G. E, Hamman, Brian D, Rice, Dennis S, Rawlins, David B

“…The structure of LX7101, a dual LIM-kinase and ROCK inhibitor for the treatment of ocular hypertension and associated glaucoma, is disclosed. Previously…”
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Hsp27 Upregulation by HIF-1 Signaling Offers Protection against Retinal Ischemia in Rats by Whitlock, N. Andrew, Agarwal, Neeraj, Ma, Jian-Xing, Crosson, Craig E

“…Previous work from the authors' laboratory has shown that Hsp27 is specifically upregulated after retinal ischemic preconditioning (IPC), and this upregulation…”
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Neuroanatomy of a diplodocid sauropod dinosaur from the Lower Cretaceous of Patagonia, Argentina by Garderes, Juan Pablo, Gallina, Pablo Ariel, Whitlock, John Andrew, Toledo, Néstor

“…Diplodocid neuroanatomy is known from four Late Jurassic forms from North America and Africa. Recently, a partial braincase of a diplodocid sauropod (MMCh-Pv-…”
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Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK by Whitlock, N Andrew, Harrison, Bryce, Mixon, Travis, Yu, Xiang-Qing, Wilson, Alan, Gerhardt, Brenda, Eberhart, Derek E, Abuin, Alejandro, Rice, Dennis S

“…Goals of this study were to determine if pharmacological or genetic inhibition of Rho-associated coiled coil containing protein kinases (known as ROCK1 and…”
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Heat Shock Protein 27 Delays Ca2+-Induced Cell Death in a Caspase-Dependent and -Independent Manner in Rat Retinal Ganglion Cells by Whitlock, N. Andrew, Lindsey, Kristie, Agarwal, Neeraj, Crosson, Craig E, Ma, Jian-Xing

“…Hsp27 is a well-characterized and studied antiapoptotic protein. A recent study reported that Hsp27 is upregulated in the retina after retinal ischemic…”
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Rapid estimation of canopy nitrogen of cereal crops at paddock scale using a Canopy Chlorophyll Content Index by Perry, Eileen M., Fitzgerald, Glenn J., Nuttall, James G., O’Leary, Garry J., Schulthess, Urs, Whitlock, Andrew

“…Rising nitrogen (N) fertiliser costs and concerns over environmental impacts have emphasized the need for rapid, non-destructive, paddock-scale tools to…”
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Paleoecology and Systematics of the Diplodocoid Sauropods by Whitlock, John Andrew

“…Diplodocoid sauropods were among the most successful and largest herbivores of the Mesozoic. Here, the systematics and paleoecology of these animals are…”
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Heat Shock Protein 27 Delays Ca 2+ -Induced Cell Death in a Caspase-Dependent and -Independent Manner in Rat Retinal Ganglion Cells by Whitlock, N. Andrew, Lindsey, Kristie, Agarwal, Neeraj, Crosson, Craig E., Ma, Jian-Xing

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The role and regulation of heat shock protein 27 in retinal ischemic preconditioning by Whitlock, Norris Andrew

“…Introduction. Vision loss resulting from retinal ischemia is associated with several systemic and ocular diseases. In the retina, ischemia is thought to lead…”
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