Search Results - "Whitington, Tom"

TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer by De Laere, Bram, Oeyen, Steffi, Mayrhofer, Markus, Whitington, Tom, van Dam, Pieter-Jan, Van Oyen, Peter, Ghysel, Christophe, Ampe, Jozef, Ost, Piet, Demey, Wim, Hoekx, Lucien, Schrijvers, Dirk, Brouwers, Barbara, Lybaert, Willem, Everaert, Els G, De Maeseneer, Daan, Strijbos, Michiel, Bols, Alain, Fransis, Karen, Beije, Nick, de Kruijff, Inge E, van Dam, Valerie, Brouwer, Anja, Goossens, Dirk, Heyrman, Lien, Van den Eynden, Gert G, Rutten, Annemie, Del Favero, Jurgen, Rantalainen, Mattias, Rajan, Prabhakar, Sleijfer, Stefan, Ullén, Anders, Yachnin, Jeffrey, Grönberg, Henrik, Van Laere, Steven J, Lindberg, Johan, Dirix, Luc Y

“…To infer the prognostic value of simultaneous androgen receptor ( ) and profiling in liquid biopsies from patients with metastatic castration-resistant…”
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Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns by De Laere, Bram, van Dam, Pieter-Jan, Whitington, Tom, Mayrhofer, Markus, Diaz, Emanuela Henao, Van den Eynden, Gert, Vandebroek, Jean, Del-Favero, Jurgen, Van Laere, Steven, Dirix, Luc, Grönberg, Henrik, Lindberg, Johan

“…Abstract Background Expression of the androgen receptor splice variant 7 (AR-V7) is associated with poor response to second-line endocrine therapy in…”
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Inferring transcription factor complexes from ChIP-seq data by Whitington, Tom, Frith, Martin C, Johnson, James, Bailey, Timothy L

“…Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) allows researchers to determine the genome-wide binding locations of individual…”
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The value of position-specific priors in motif discovery using MEME by Bailey, Timothy L, Bodén, Mikael, Whitington, Tom, Machanick, Philip

“…Position-specific priors have been shown to be a flexible and elegant way to extend the power of Gibbs sampler-based motif discovery algorithms. Information of…”
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Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis by Mayrhofer, Markus, De Laere, Bram, Whitington, Tom, Van Oyen, Peter, Ghysel, Christophe, Ampe, Jozef, Ost, Piet, Demey, Wim, Hoekx, Lucien, Schrijvers, Dirk, Brouwers, Barbara, Lybaert, Willem, Everaert, Els, De Maeseneer, Daan, Strijbos, Michiel, Bols, Alain, Fransis, Karen, Oeyen, Steffi, van Dam, Pieter-Jan, Van den Eynden, Gert, Rutten, Annemie, Aly, Markus, Nordström, Tobias, Van Laere, Steven, Rantalainen, Mattias, Rajan, Prabhakar, Egevad, Lars, Ullén, Anders, Yachnin, Jeffrey, Dirix, Luc, Grönberg, Henrik, Lindberg, Johan

“…There are multiple existing and emerging therapeutic avenues for metastatic prostate cancer, with a common denominator, which is the need for predictive…”
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A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells by Tallack, Michael R, Whitington, Tom, Yuen, Wai Shan, Wainwright, Elanor N, Keys, Janelle R, Gardiner, Brooke B, Nourbakhsh, Ehsan, Cloonan, Nicole, Grimmond, Sean M, Bailey, Timothy L, Perkins, Andrew C

“…KLF1 regulates a diverse suite of genes to direct erythroid cell differentiation from bipotent progenitors. To determine the local cis-regulatory contexts and…”
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Epigenetic priors for identifying active transcription factor binding sites by Cuellar-Partida, Gabriel, Buske, Fabian A., McLeay, Robert C., Whitington, Tom, Noble, William Stafford, Bailey, Timothy L.

“…Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for…”
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High-throughput chromatin information enables accurate tissue-specific prediction of transcription factor binding sites by Whitington, Tom, Perkins, Andrew C, Bailey, Timothy L

“…In silico prediction of transcription factor binding sites (TFBSs) is central to the task of gene regulatory network elucidation. Genomic DNA sequence…”
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Prevalence and heterogeneity of androgen receptor splice variants and intra-AR structural variation in patient with castration-resistant prostate cancer by Dirix, Luc Yves, De Laere, Bram, van Dam, Pieter-Jan, Whitington, Tom, Mayrhofer, Markus, Henao Diaz, Emanuela, Van den Eynden, Gert, Vandebroek, Jean, Del-Favero, Jurgen, Van Laere, Steven J, Gronberg, Henrik, Lindberg, Johan

“…Abstract only 11530 Background: Androgen receptor splice variant 7 (AR-V7) is linked to a priori resistance to abiraterone acetate and enzalutamide. However,…”
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Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer by De Laere, Bram, Rajan, Prabhakar, Grönberg, Henrik, Dirix, Luc, Lindberg, Johan

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Improved prediction of transcription binding sites from chromatin modification data by Sato, Kengo, Whitington, Tom, Bailey, Timothy L, Horton, Paul

“…In this paper we apply machine learning to the task of predicting transcription factor binding sites by combining information on multiple forms of chromatin…”
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