Search Results - "Whiteside, G.T"

Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease by Strassle, B.W, Mark, L, Leventhal, L, Piesla, M.J, Jian Li, X, Kennedy, J.D, Glasson, S.S, Whiteside, G.T

“…Summary Objective To investigate the relationship between efficacy of a bisphosphonate, pain and extent of joint damage in the monosodium iodoacetate (MIA)…”
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Predictive validity of animal pain models? A comparison of the pharmacokinetic–pharmacodynamic relationship for pain drugs in rats and humans by Whiteside, G.T., Adedoyin, A., Leventhal, L.

“…A number of previous reviews have very eloquently summarized pain models and endpoints in animals. Many of these reviews also discuss how animal models have…”
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Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression by Hughes, Z.A., Neal, S.J., Smith, D.L., Sukoff Rizzo, S.J., Pulicicchio, C.M., Lotarski, S., Lu, S., Dwyer, J.M., Brennan, J., Olsen, M., Bender, C.N., Kouranova, E., Andree, T.H., Harrison, J.E., Whiteside, G.T., Springer, D., O'Neil, S.V., Leonard, S.K., Schechter, L.E., Dunlop, J., Rosenzweig-Lipson, S., Ring, R.H.

“…Evidence suggests that 30–50% of patients suffering from major depressive disorder (MDD) are classified as suffering from treatment resistant depression (TRD)…”
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Cell death in the superficial dorsal horn in a model of neuropathic pain by Whiteside, G.T., Munglani, R.

“…The aims of this study were to investigate the occurrence of apoptotic cell death in the dorsal horn of the adult rat spinal cord following chronic…”
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Measuring and realizing the translational significance of preclinical in vivo studies of painful osteoarthritis by Hummel, Michele, Whiteside, Garth T

“…Summary In this communication, we discuss some key issues surrounding the translation of preclinical efficacy studies in models of painful osteoarthritis to…”
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