Search Results - "Whitehouse, B J"

Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans by Ramracheya, R. D, Muller, D. S, Wu, Y, Whitehouse, B. J, Huang, G. C, Amiel, S. A, Karalliedde, J, Viberti, G, Jones, P. M, Persaud, S. J

“…Aims/hypothesis This study aimed to identify the expression of angiotensin II receptors in isolated human islets and beta cells and to examine the functional…”
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ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans by Al-Majed, HT, Jones, PM, Persaud, SJ, Sugden, D, Huang, GC, Amiel, S, Whitehouse, BJ

“…It has previously been suggested that ACTH and ACTH-related peptides may act as paracrine modulators of insulin secretion in the islets of Langerhans. We have,…”
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Cyclic AMP-induced expression of steroidogenic acute regulatory protein is dependent upon phosphoprotein phosphatase activities by Jones, PM, Sayed, SB, Persaud, SJ, Burns, CJ, Gyles, S, Whitehouse, BJ

“…In addition to the well-documented role of protein kinases in the regulation of steroid production, phosphoprotein phosphatase (PP) activity is required for…”
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Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases by Whitehouse, BJ, Gyles, SL, Squires, PE, Sayed, SB, Burns, CJ, Persaud, SJ, Jones, PM

“…Y1 adrenocortical cells respond to activators of the cyclic AMP-dependent protein kinase (PKA) signalling pathway not only with increases in steroid secretion…”
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Phosphoserine/threonine phosphatases in the rat adrenal cortex: a role in the control of steroidogenesis? by SAYED, S. B, WHITEHOUSE, B. J, JONES, P. M

“…The involvement of protein kinases in the signal transduction pathways controlling adrenal steroidogenesis is well established, and the phosphorylation of…”
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Adrenal mast cells modulate vascular and secretory responses in the intact adrenal gland of the rat by Hinson, J P, Vinson, G P, Pudney, J, Whitehouse, B J

“…Mast cells were identified in the rat adrenal gland, located in the walls of arterioles at the point at which they penetrate the connective tissue capsule. The…”
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Adrenocortical Function in a New World Primate, the Marmoset Monkey, Callithrix jacchus by Whitehouse, B.J., Abayasekara, D.R.E.

“…The function of the adrenal cortex of the marmoset monkey Callithrix jacchus has been investigated. In common with other New World primates, these animals seem…”
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Benzodiazepines and steroidogenesis by Whitehouse, B J

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ERKs Regulate Cyclic AMP-induced Steroid Synthesis through Transcription of the Steroidogenic Acute Regulatory (StAR) Gene by Gyles, Shân L., Burns, Chris J., Whitehouse, Barbara J., Sugden, David, Marsh, Phil J., Persaud, Shanta J., Jones, Peter M.

“…Cyclic AMP-dependent expression of the steroidogenic acute regulatory (StAR) protein is thought to be the controlling step for steroid production, but the…”
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The mammalian adrenal circulation and the relationship between adrenal blood flow and steroidogenesis by Vinson, G P, Pudney, J A, Whitehouse, B J

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Roles of type I and type II isoenzymes of cyclic AMP-dependent protein kinase in steroidogenesis in rat adrenal cells by Whitehouse, B J, Abayasekara, D R

“…The role played by cyclic AMP (cAMP)-dependent protein kinases (PKAs) in rat adrenal steroidogenesis has been investigated using cAMP analogues which show…”
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Stimulation of steroidogenesis by forskolin in rat adrenal zona glomerulosa cell preparations by Purdy, S J, Whitehouse, B J, Abayasekara, D R

“…The actions of forskolin have been investigated to determine to what extent its effects on steroidogenesis in rat adrenal preparations are dependent on…”
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Lipocortins, mediators of the anti-inflammatory actions of corticosteroids? by Whitehouse, B J

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Monoclonal antibodies against rat adrenocortical cell antigens by Laird, S M, Vinson, G P, Whitehouse, B J

“…Cell lines secreting antibodies directed against rat adrenocortical cell antigens have been produced using hybridoma techniques. As tested by immunofluorescent…”
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Effects of chronic corticotrophin treatment on aldosterone metabolism in the rat by Abayasekara, D R, Onyezili, N I, Whitehouse, B J, Laird, S M, Vinson, G P

“…Chronic treatment with high doses of ACTH leads to marked reduction in aldosterone biosynthesis and secretion both in vivo and in vitro. In contrast, it has…”
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Oxytocin and arginine vasopressin stimulate steroid secretion by the isolated perfused rat adrenal gland by Hinson, J P, Vinson, G P, Porter, I D, Whitehouse, B J

“…Using the intact isolated perfused rat adrenal preparation we have shown for the first time a direct effect of oxytocin on adrenocortical steroid secretion…”
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The relationship between perfusion medium flow rate and steroid secretion in the isolated perfused rat adrenal gland in situ by Hinson, J P, Vinson, G P, Whitehouse, B J

“…Using the in-situ, isolated, perfused rat adrenal preparation, we have investigated the effects of changes in the rate of perfusate flow through the gland,…”
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Effects of dopamine, high potassium concentration and field stimulation on the secretion of aldosterone by the perfused rat adrenal gland by Porter, I D, Whitehouse, B J, Price, G M, Hinson, J P, Vinson, G P

“…The rat adrenal cortex contains quantities of dopamine that are compatible with its function as a neurotransmitter, suggesting that locally released dopamine…”
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Studies on the mechanisms of ACTH-induced inhibition of aldosterone biosynthesis in the rat adrenal cortex by Abayasekara, D R, Vazir, H, Whitehouse, B J, Price, G M, Hinson, J P, Vinson, G P

“…In rats, chronic treatment with high doses of ACTH (10-40 micrograms/100 g body weight per day) leads to a marked reduction in aldosterone synthesis by adrenal…”
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Inhibition of corticosteroid production by sodium pentobarbitone in rat adrenocortical preparations by Whitehouse, B J, Purdy, S J, Abayasekara, D R

“…It is possible that some of the effects of sodium pentobarbitone on the hypothalamo-pituitary-adrenal axis in the intact animal may be attributable to direct…”
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