Search Results - "White, Wendy M."

Preeclampsia and cognitive impairment later in life by Fields, Julie A., PhD, Garovic, Vesna D., MD, Mielke, Michelle M., PhD, Kantarci, Kejal, MD, Jayachandran, Muthuvel, PhD, White, Wendy M., MD, Butts, Alissa M., PhD, Graff-Radford, Jonathan, MD, Lahr, Brian D., MS, Bailey, Kent R., PhD, Miller, Virginia M., PhD

“…Background Hypertension is a risk factor for cerebrovascular disease and cognitive impairment. Women with hypertensive episodes during pregnancy report…”
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A history of preeclampsia is associated with a risk for coronary artery calcification 3 decades later by White, Wendy M., MD, Mielke, Michelle M., PhD, Araoz, Philip A., MD, Lahr, Brian D, Bailey, Kent R., PhD, Jayachandran, Muthuvel, PhD, Miller, Virginia M., PhD, Garovic, Vesna D., MD

“…Background A history of preeclampsia is an independent risk factor for cardiac events and stroke. Changes in vasculature structure that contribute to these…”
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Early Onset Preeclampsia Is Associated With Glycocalyx Degradation and Reduced Microvascular Perfusion by Weissgerber, Tracey L, Garcia-Valencia, Oscar, Milic, Natasa M, Codsi, Elizabeth, Cubro, Hajrunisa, Nath, Meryl C, White, Wendy M, Nath, Karl A, Garovic, Vesna D

“…Background The endothelial glycocalyx is a vasoprotective barrier between the blood and endothelium. We hypothesized that glycocalyx degradation is present in…”
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Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types by Onuchic, Vitor, Hartmaier, Ryan J., Boone, David N., Samuels, Michael L., Patel, Ronak Y., White, Wendy M., Garovic, Vesna D., Oesterreich, Steffi, Roth, Matt E., Lee, Adrian V., Milosavljevic, Aleksandar

“…Cancer progression depends on both cell-intrinsic processes and interactions between different cell types. However, large-scale assessment of cell type…”
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Urinary Extracellular Vesicles of Podocyte Origin and Renal Injury in Preeclampsia by Gilani, Sarwat I, Anderson, Ulrik Dolberg, Jayachandran, Muthuvel, Weissgerber, Tracey L, Zand, Ladan, White, Wendy M, Milic, Natasa, Suarez, Maria Lourdes Gonzalez, Vallapureddy, Rangit Reddy, Nääv, Åsa, Erlandsson, Lena, Lieske, John C, Grande, Joseph P, Nath, Karl A, Hansson, Stefan R, Garovic, Vesna D

“…Renal histologic expression of the podocyte-specific protein, nephrin, but not podocin, is reduced in preeclamptic compared with normotensive pregnancies. We…”
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Long QT Syndrome–Associated Mutations in Intrauterine Fetal Death by Crotti, Lia, Tester, David J, White, Wendy M, Bartos, Daniel C, Insolia, Roberto, Besana, Alessandra, Kunic, Jennifer D, Will, Melissa L, Velasco, Ellyn J, Bair, Jennifer J, Ghidoni, Alice, Cetin, Irene, Van Dyke, Daniel L, Wick, Myra J, Brost, Brian, Delisle, Brian P, Facchinetti, Fabio, George, Alfred L, Schwartz, Peter J, Ackerman, Michael J

“…IMPORTANCE Intrauterine fetal death or stillbirth occurs in approximately 1 out of every 160 pregnancies and accounts for 50% of all perinatal deaths…”
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Impaired Cognition and Brain Atrophy Decades After Hypertensive Pregnancy Disorders by Mielke, Michelle M, Milic, Natasa M, Weissgerber, Tracey L, White, Wendy M, Kantarci, Kejal, Mosley, Thomas H, Windham, B Gwen, Simpson, Brittany N, Turner, Stephen T, Garovic, Vesna D

“…Hypertensive pregnancy disorders have been associated with subjective cognitive complaints or brain white-matter lesions 5 to 10 years after the hypertensive…”
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Posterior Reversible Encephalopathy Syndrome and Eclampsia: Pressing the Case for More Aggressive Blood Pressure Control by Wagner, Steven J., MD, Acquah, Letitia A., MD, Lindell, E. Paul, MD, Craici, Iasmina M., MD, Wingo, Majken T., MD, Rose, Carl H., MD, White, Wendy M., MD, August, Phyllis, MD, Garovic, Vesna D., MD

“…OBJECTIVE To assess the prevalence, clinical presentations, and neuroimaging abnormalities in a series of patients treated for eclampsia at Mayo Clinic in…”
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Obstetric Nephrology: Lupus and Lupus Nephritis in Pregnancy by Stanhope, Todd J, White, Wendy M, Moder, Kevin G, Smyth, Andrew, Garovic, Vesna D

“…SLE is a multi-organ autoimmune disease that affects women of childbearing age. Renal involvement in the form of either active lupus nephritis (LN) at the time…”
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Targeting senescence improves angiogenic potential of adipose-derived mesenchymal stem cells in patients with preeclampsia by Suvakov, Sonja, Cubro, Hajrunisa, White, Wendy M, Butler Tobah, Yvonne S, Weissgerber, Tracey L, Jordan, Kyra L, Zhu, Xiang Y, Woollard, John R, Chebib, Fouad T, Milic, Natasa M, Grande, Joseph P, Xu, Ming, Tchkonia, Tamara, Kirkland, James L, Lerman, Lilach O, Garovic, Vesna D

“…Preeclampsia is a pregnancy-specific hypertensive disorder characterized by impaired angiogenesis. We postulate that senescence of mesenchymal stem cells…”
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Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury by White, Wendy M, Garrett, Angelica T, Craici, Iasmina M, Wagner, Steven J, Fitz-Gibbon, Patrick D, Butters, Kim A, Brost, Brian C, Rose, Carl H, Grande, Joseph P, Garovic, Vesna D

“…Studies have shown that podocyturia, i.e., urinary loss of viable podocytes (glomerular epithelial cells), is associated with proteinuria in preeclampsia. We…”
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Cohort profile: the Olmsted County hypertensive disorders of pregnancy (HDP) cohort using the Rochester Epidemiology Project by Vaughan, Lisa, White, Wendy M, Tobah, Yvonne S Butler, Kattah, Andrea, Parashuram, Santosh, Gunaratne, Madugodarlalalage D, Vermunt, Jane V, Mielke, Michelle, Milic, Natasa M, Suvakov, Sonja, Bielinski, Suzette, Chamberlain, Alanna M, Garovic, Vesna D

“…PurposeThe Olmsted County hypertensive disorders of pregnancy (HDP) cohort is a population-based retrospective study designed to compare the incidence of HDP…”
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Epigenetic and senescence markers indicate an accelerated ageing-like state in women with preeclamptic pregnancies by Suvakov, Sonja, Ghamrawi, Ranine, Cubro, Hajrunisa, Tu, Haitao, White, Wendy M., Tobah, Yvonne S. Butler, Milic, Natasa M., Grande, Joseph P., Cunningham, Julie M., Chebib, Fouad T., Prata, Larissa G.P. Langhi, Zhu, Yi, Tchkonia, Tamara, Kirkland, James L., Nath, Karl A., Milosavljevic, Aleksandar, Garovic, Vesna D.

“…Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria and/or multisystem involvement. Disease-specific therapy has yet to be…”
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Impact of a History of Hypertension in Pregnancy on Later Diagnosis of Atrial Fibrillation by Scantlebury, Dawn C., Kattah, Andrea G., Weissgerber, Tracey L., Agarwal, Sanket, Mielke, Michelle M., Weaver, Amy L., Vaughan, Lisa E., Henkin, Stanislav, Zimmerman, Katherine, Miller, Virginia M., White, Wendy M., Hayes, Sharonne N., Garovic, Vesna D.

“…Background Atrial fibrillation/flutter (AF) produces significant morbidity in women and is typically attributed to cardiac remodeling from multiple causes,…”
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Batch effect correction for genome-wide methylation data with Illumina Infinium platform by Sun, Zhifu, Chai, High Seng, Wu, Yanhong, White, Wendy M, Donkena, Krishna V, Klein, Christopher J, Garovic, Vesna D, Therneau, Terry M, Kocher, Jean-Pierre A

“…Genome-wide methylation profiling has led to more comprehensive insights into gene regulation mechanisms and potential therapeutic targets. Illumina Human…”
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Incidence and Long-Term Outcomes of Hypertensive Disorders of Pregnancy by Garovic, Vesna D., White, Wendy M., Vaughan, Lisa, Saiki, Mie, Parashuram, Santosh, Garcia-Valencia, Oscar, Weissgerber, Tracey L., Milic, Natasa, Weaver, Amy, Mielke, Michelle M.

“…Hypertensive disorders of pregnancy (HDP) are associated with increased risks for cardiovascular disease later in life. The HDP incidence is commonly assessed…”
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Buffy Coat DNA Methylation Profile Is Representative of Methylation Patterns in White Blood Cell Types in Normal Pregnancy by Ghamrawi, Ranine, Velickovic, Igor, Milicevic, Ognjen, White, Wendy M, Thistlethwaite, Lillian Rosa, Cunningham, Julie M, Milosavljevic, Aleksandar, Milic, Natasa M, Garovic, Vesna D

“…We aimed to assess the extent to which the buffy coat DNA methylome is representative of methylation patterns in constitutive white blood cell (WBC) types in…”
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Maternal and Neonatal Complications of Elective Early-Term Deliveries by Jensen, Jani R., MD, White, Wendy M., MD, Coddington, Charles C., MD

“…Abstract Approximately 10% to 15% of all deliveries in the United States are performed before 39 completed weeks of gestation without a true medical indication…”
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Hypertension in pregnancy is associated with elevated homocysteine levels later in life by White, Wendy M., MD, Turner, Stephen T., MD, Bailey, Kent R., PhD, Mosley, Thomas H., PhD, Kardia, Sharon L.R., PhD, Wiste, Heather J., BA, Kullo, Iftikhar J., MD, Garovic, Vesna D., MD

“…Objective Hyperhomocysteinemia is associated with an elevated cardiovascular disease risk. We examined whether women with a history of hypertension in…”
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Normal early pregnancy: A transient state of epigenetic change favoring hypomethylation by White, Wendy M., Brost, Brian C., Sun, Zhifu, Rose, Carl, Craici, Iasmina, Wagner, Steven J., Turner, Stephen, Garovic, Vesna D.

“…The objective of this study was to analyze genome-wide differential methylation patterns in maternal leukocyte DNA in early pregnant and non-pregnant states…”
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