Search Results - "White, Tayleur D."
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Differential lipid signaling from CD4 + and CD8 + T cells contributes to type 1 diabetes development
Published in Frontiers in immunology (18-09-2024)“…We reported that Ca -independent phospholipase A β (iPLA β)-derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4 and CD8 T cells are…”
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The Impact of the Ca2+-Independent Phospholipase A2β (iPLA2β) on Immune Cells
Published in Biomolecules (Basel, Switzerland) (15-04-2021)“…The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including…”
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3
Macrophage polarization is linked to Ca2+-independent phospholipase A2β-derived lipids and cross-cell signaling in mice[S]
Published in Journal of lipid research (01-02-2020)“…Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can…”
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4
iPLA 2 β and its role in male fertility, neurological disorders, metabolic disorders, and inflammation
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-06-2019)“…The Ca -independent phospholipases, designated as group VI iPLA s, also referred to as PNPLAs due to their shared homology with patatin, include the β, γ, δ,…”
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5
iPLA2β and its role in male fertility, neurological disorders, metabolic disorders, and inflammation
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-06-2019)“…The Ca2+-independent phospholipases, designated as group VI iPLA2s, also referred to as PNPLAs due to their shared homology with patatin, include the β, γ, δ,…”
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Selective Reduction of Ca2+-Independent Phospholipase A2β (iPLA2β)-Derived Lipid Signaling from Macrophages Mitigates Type 1 Diabetes Development
Published in Diabetes (New York, N.Y.) (16-09-2024)“…Type 1 diabetes (T1D) is a consequence of autoimmune destruction of β-cells and macrophages (MΦ) have a central role in initiating processes that lead to…”
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7
The Impact of the Ca 2+ -Independent Phospholipase A 2 β (iPLA 2 β) on Immune Cells
Published in Biomolecules (Basel, Switzerland) (15-04-2021)“…The Ca -independent phospholipase A β (iPLA β) is a member of the PLA family that has been proposed to have roles in multiple biological processes including…”
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Journal Article -
8
Macrophage polarization is linked to Ca 2+ -independent phospholipase A 2 β-derived lipids and cross-cell signaling in mice
Published in Journal of lipid research (01-02-2020)“…Phospholipases A (PLA s) catalyze hydrolysis of the -2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be…”
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