Search Results - "White, Shana"

Harmonization of transcriptomic and methylomic analysis in environmental epidemiology studies for potential application in chemical risk assessment by Kim, Stephanie, White, Shana M., Radke, Elizabeth G., Dean, Jeffry L.

“…Recent efforts have posited the utility of transcriptomic-based approaches to understand chemical-related perturbations in the context of human health risk…”
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Pharmacological inhibition of apical sodium‐dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice by Miethke, Alexander G., Zhang, Wujuan, Simmons, Julia, Taylor, Amy E., Shi, Tiffany, Shanmukhappa, Shiva Kumar, Karns, Rebekah, White, Shana, Jegga, Anil G., Lages, Celine S., Nkinin, Stephenson, Keller, Bradley T., Setchell, Kenneth D.R.

“…Deficiency of multidrug resistance 2 (mdr2), a canalicular phospholipid floppase, leads to excretion of low‐phospholipid “toxic” bile causing progressive…”
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Connecting omics signatures and revealing biological mechanisms with iLINCS by Pilarczyk, Marcin, Fazel-Najafabadi, Mehdi, Kouril, Michal, Shamsaei, Behrouz, Vasiliauskas, Juozas, Niu, Wen, Mahi, Naim, Zhang, Lixia, Clark, Nicholas A., Ren, Yan, White, Shana, Karim, Rashid, Xu, Huan, Biesiada, Jacek, Bennett, Mark F., Davidson, Sarah E., Reichard, John F., Roberts, Kurt, Stathias, Vasileios, Koleti, Amar, Vidovic, Dusica, Clarke, Daniel J. B., Schürer, Stephan C., Ma’ayan, Avi, Meller, Jarek, Medvedovic, Mario

“…There are only a few platforms that integrate multiple omics data types, bioinformatics tools, and interfaces for integrative analyses and visualization that…”
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The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach by Engevik, Amy C, Feng, Rui, Choi, Eunyoung, White, Shana, Bertaux-Skeirik, Nina, Li, Jing, Mahe, Maxime M, Aihara, Eitaro, Yang, Li, DiPasquale, Betsy, Oh, Sunghee, Engevik, Kristen A, Giraud, Andrew S, Montrose, Marshall H, Medvedovic, Mario, Helmrath, Michael A, Goldenring, James R, Zavros, Yana

“…Background & Aims During aging, physiological changes in the stomach result in more tenuous gastric tissue that is less capable of repairing injury, leading to…”
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P540: Clinical implementation of carrier screening and diagnostic testing for spinal muscular atrophy using PCR/capillary electrophoresis assay by Qiao, Wanqiong, Ho, Chandler, Villanueva, Litz, Hale, Caitlin, Chen, Lei, Liao, Linda, Reavey, Caitlin, Shi, Huanzhi, Hammond, Nathan, White, Shana

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Cognitive Performance Scores for the Pediatric Automated Neuropsychological Assessment Metrics in Childhood‐Onset Systemic Lupus Erythematosus by Vega‐Fernandez, Patricia, Vanderburgh White, Shana, Zelko, Frank, Ruth, Natasha M., Levy, Deborah M., Muscal, Eyal, Klein‐Gitelman, Marisa S., Huber, Adam M., Tucker, Lori B., Roebuck‐Spencer, Tresa, Ying, Jun, Brunner, Hermine I.

“…Objective To develop and initially validate a global cognitive performance score (CPS) for the Pediatric Automated Neuropsychological Assessment Metrics…”
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A Biologic Combination of Lenalidomide and Rituximab for Front-Line Therapy of Indolent B-Cell Non-Hodgkin's Lymphoma by Fowler, Nathan, McLaughlin, Peter, Hagemeister, Fredrick B., Kwak, Larry, Fanale, Michelle, Neelapu, Sattva, Fayad, Luis, Pro, Barbara, Sergent, Crystal, White, Shana R.S., Samaniego, Felipe

“…Abstract 1714▪▪This icon denotes an abstract that is clinically relevant. Poster Board I-740 Despite advances in therapy and a better understanding of the…”
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A Quantitative Assessment of Tremor and Ataxia in Female FMR1 Premutation Carriers Using CATSYS by Narcisa, Vivien, Aguilar, Dalila, Nguyen, Danh V., Campos, Luis, Brodovsky, Jeffrey, White, Shana, Adams, Patrick, Tassone, Flora, Hagerman, Paul J., Hagerman, Randi J.

“…The fragile X-associated tremor/ataxia syndrome (FXTAS) is a relatively common cause of balance problems leading to gait disturbances in older males (40%) with…”
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Advancing culturally responsive-sustaining computer science through K-12 teacher professional development strategies by White, Shana V., Koshy, Sonia, Scott, Allison

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Assessment of network module identification across complex diseases by Choobdar, Sarvenaz, Ahsen, Mehmet E., Crawford, Jake, Tomasoni, Mattia, Fang, Tao, Lamparter, David, Lin, Junyuan, Hescott, Benjamin, Hu, Xiaozhe, Mercer, Johnathan, Natoli, Ted, Narayan, Rajiv, Subramanian, Aravind, Zhang, Jitao D., Stolovitzky, Gustavo, Kutalik, Zoltán, Lage, Kasper, Slonim, Donna K., Saez-Rodriguez, Julio, Cowen, Lenore J., Bergmann, Sven, Marbach, Daniel

“…Many bioinformatics methods have been proposed for reducing the complexity of large gene or protein networks into relevant subnetworks or modules. Yet, how…”
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Application and Development of Novel Methods for Pathway Analysis and Visualization of the LINCS L1000 Dataset by White, Shana

“…The LINCS L1000 dataset is a large-scale compendium that contains records of the cell line specific transcriptional effects of cellular perturbation that was…”
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Rapid Genome Sequencing in the Critically Ill by Buchan, Jillian G, White, Shana, Joshi, Ruchi, Ashley, Euan A

“…Solutions such as these address the accelerated processing and storage needed for the massive amounts of data generated by rGS, although these tools focus on…”
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Loss-of-function variants in SRRM2 cause a neurodevelopmental disorder by Cuinat, Silvestre, Nizon, Mathilde, Isidor, Bertrand, Stegmann, Alexander, van Jaarsveld, Richard H., van Gassen, Koen L., van der Smagt, Jasper J., Volker-Touw, Catharina M.L., Holwerda, Sjoerd J.B., Terhal, Paulien A., Schuhmann, Sarah, Vasileiou, Georgia, Khalifa, Mohamed, Nugud, Alaa A., Yasaei, Hemad, Ousager, Lilian Bomme, Brasch-Andersen, Charlotte, Deb, Wallid, Besnard, Thomas, Simon, Marleen E.H., Amsterdam, Karin Huijsdens-van, Verbeek, Nienke E., Matalon, Dena, Dykzeul, Natalie, White, Shana, Spiteri, Elizabeth, Devriendt, Koen, Boogaerts, Anneleen, Willemsen, Marjolein, Brunner, Han G., Sinnema, Margje, De Vries, Bert B.A., Gerkes, Erica H., Pfundt, Rolph, Izumi, Kosuke, Krantz, Ian D., Xu, Zhou L., Murrell, Jill R., Valenzuela, Irene, Cusco, Ivon, Rovira-Moreno, Eulàlia, Yang, Yaping, Bizaoui, Varoona, Patat, Olivier, Faivre, Laurence, Tran-Mau-Them, Frederic, Vitobello, Antonio, Denommé-Pichon, Anne-Sophie, Philippe, Christophe, Bezieau, Stéphane, Cogné, Benjamin

“…SRRM2 encodes the SRm300 protein, a splicing factor of the SR-related protein family characterized by its serine- and arginine-enriched domains. It promotes…”
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Data sharing as a national quality improvement program: reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR) by Lebo, Matthew S, Zakoor, Kathleen-Rose, Chun, Kathy, Speevak, Marsha D, Waye, John S, McCready, Elizabeth, Parboosingh, Jillian S, Lamont, Ryan E, Feilotter, Harriet, Bosdet, Ian, Tucker, Tracy, Young, Sean, Karsan, Aly, Charames, George S, Agatep, Ronald, Spriggs, Elizabeth L, Chisholm, Caitlin, Vasli, Nasim, Daoud, Hussein, Jarinova, Olga, Tomaszewski, Robert, Hume, Stacey, Taylor, Sherryl, Akbari, Mohammad R, Lerner-Ellis, Jordan

“…Purpose The purpose of this study was to develop a national program for Canadian diagnostic laboratories to compare DNA-variant interpretations and resolve…”
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Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations by Lerner-Ellis, Jordan, Wang, Marina, White, Shana, Lebo, Matthew S

“…The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical…”
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Pharmacological inhibition of ASBT changes bile composition and blocks progression of sclerosing cholangitis in mdr2 knockout mice by Miethke, Alexander G, Zhang, Wujuan, Simmons, Julie, Taylor, Amy, Shi, Tiffany, Shanmukhappa, Shiva Kumar, Karns, Rebekah, White, Shana, Jegga, Anil G, Lages, Celine S, Nkinin, Stephenson, Keller, Bradley T, Setchell, Kenneth D. R.

“…Deficiency for mdr2, a canalicular phospholipid floppase, leads to excretion of low phospholipid “toxic” bile causing progressive cholestasis. We hypothesize…”
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Developing a genomics rotation: Practical training around variant interpretation for genetic counseling students by White, Shana, Fisk, Dianna G., Rego, Shannon, Kohler, Jennefer N., Reuter, Chloe M., Bonner, Devon, Wheeler, Matthew T., Ormond, Kelly E., Hanson‐Kahn, Andrea K., Adams, David R., Aday, Aaron, Bacino, Carlos A., Balasubramanyam, Ashok, Barseghyan, Hayk, Batzli, Gabriel F., Bellen, Hugo J., Bernstein, Jonathan A., Bostwick, Bret L., Briere, Lauren C., Brokamp, Elly, Burrage, Lindsay C., Butte, Manish J., Chen, Shan, Clark, Gary D., Coakley, Terra R., Cogan, Joy D., Cope, Heidi, Craigen, William J., D'Souza, Precilla, Dayal, Jyoti G., Dorrani, Naghmeh, Enns, Gregory M., Estwick, Tyra, Fernandez, Liliana, Ferreira, Carlos, Fisher, Paul G., Fogel, Brent L., Gahl, William A., Gourdine, Jean‐Philippe F., Gropman, Andrea L., Haendel, Melissa, Johnston, Jean M., Krasnewich, Donna M., Lalani, Seema R., Lee, Brendan H., Levy, Shawn E., Lincoln, Sharyn A., Loo, Sandra K., Loscalzo, Joseph, Maas, Richard L., Macnamara, Ellen F., MacRae, Calum A., Maduro, Valerie V., Majcherska, Marta M., Mamounas, Laura A., Marom, Ronit, Martin, Martin G., Martínez‐Agosto, Julian A., Marwaha, Shruti, McCormack, Colleen E., Might, Matthew, Morimoto, Marie, Mulvihill, John J., Murdock, David R., Murphy, Jennifer L., Scott Newberry, J., Nicholas, Sarah K., Novacic, Donna, Orange, Jordan S., Carl Pallais, J., Parker, Neil H., Potocki, Lorraine, Pusey, Barbara N., Reuter, Chloe M., Rives, Lynette, Robertson, Amy K., Rodan, Lance H., Sampson, Jacinda B., Samson, Susan L., Schoch, Kelly, Shashi, Vandana, Silverman, Edwin K., Sinsheimer, Janet S., Smith, Kevin S., Sullivan, Jennifer A., Tifft, Cynthia J., Urv, Tiina K., Vilain, Eric, Walley, Nicole M., Walsh, Chris A., Wangler, Michael F., Ward, Patricia A., Worthey, Elizabeth A., Yamamoto, Shinya, Yang, John, Yang, Yaping, Yoon, Amanda J., Yu, Guoyun, Zhao, Chunli, Zheng, Allison

“…With the wide adoption of next‐generation sequencing (NGS)‐based genetic tests, genetic counselors require increased familiarity with NGS technology, variant…”
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166-P Want a good read? Next-generation HLA sequencing using the Roche 454 GS FLX platform for five NIH projects by Trachtenberg, Elizabeth, Ladner, Martha, Osoegawa, Kazu, Cohen, Franziska, Hawbecker, Sherry, Zacarias, Fernanda Ribas, Noonan, David, White, Shana, Graham, Kellie, Agraz, John, Mohr, Kathy, Vinson, Margaret, Goodridge, Damian

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The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged StomachSummary by Amy C. Engevik, Rui Feng, Eunyoung Choi, Shana White, Nina Bertaux-Skeirik, Jing Li, Maxime M. Mahe, Eitaro Aihara, Li Yang, Betsy DiPasquale, Sunghee Oh, Kristen A. Engevik, Andrew S. Giraud, Marshall H. Montrose, Mario Medvedovic, Michael A. Helmrath, James R. Goldenring, Yana Zavros

“…Background & Aims: During aging, physiological changes in the stomach result in more tenuous gastric tissue that is less capable of repairing injury, leading…”
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15-OR: A Multi-Site Study Employing High Resolution HLA Genotyping by Next Generation 454 GS FLX Sequencing by Holcomb, Cherie L, Höglund, Bryan, Anderson, Matthew W, Blake, Lisbeth A, Böhme, Irena, Egholm, Michael, Ferriola, Deborah, Gabriel, Christian, Goodridge, Damian, Klein, Rolf, Ladner, Martha, Lind, Curt, Monos, Dimitri, Pando, Marcelo, Pröll, Johannes, Sayer, David C, Schmitz-Agheguian, Gudrun, Simen, Birgitte B, Thiele, Bernhard, Trachtenberg, Elizabeth, Tyan, Dolly B, Wassmuth, Ralf, White, Shana, Erlich, Henry A

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