Search Results - "White, Ryan J"

Perspective on the Future Role of Aptamers in Analytical Chemistry by Wu, Yao, Belmonte, Israel, Sykes, Kiana S, Xiao, Yi, White, Ryan J

“…It has been almost 30 years since the invention of Systematic Evolution of Ligands by Exponential Enrichment (SELEX) methodology and the description of the…”
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Enhancing the Analytical Performance of Electrochemical RNA Aptamer-Based Sensors for Sensitive Detection of Aminoglycoside Antibiotics by Schoukroun-Barnes, Lauren R, Wagan, Samuillah, White, Ryan J

“…Folding-based electrochemical sensors utilizing structure-switching aptamers are specific, selective, sensitive, and widely applicable to the detection of a…”
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Electrochemical Aptamer-Based Sensor for Real-Time Monitoring of Insulin by Wu, Yao, Midinov, Beksultan, White, Ryan J

“…In this paper, we developed an electrochemical, aptamer-based (E-AB) for the real-time monitoring of insulin. The sensor utilizes a redox label-modified…”
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Bioinspired Protein Channel-Based Scanning Ion Conductance Microscopy (Bio-SICM) for Simultaneous Conductance and Specific Molecular Imaging by Macazo, Florika C, White, Ryan J

“…The utility of stochastic single-molecule detection using protein nanopores has found widespread application in bioanalytical sensing as a result of the…”
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Exploiting Binding-Induced Changes in Probe Flexibility for the Optimization of Electrochemical Biosensors by White, Ryan J, Plaxco, Kevin W

“…Electrochemical sensors employing redox-tagged, electrode-bound oligonucleotides have emerged as a promising new platform for the reagentless detection of…”
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Real-time, aptamer-based tracking of circulating therapeutic agents in living animals by Ferguson, Brian Scott, Hoggarth, David A, Maliniak, Dan, Ploense, Kyle, White, Ryan J, Woodward, Nick, Hsieh, Kuangwen, Bonham, Andrew J, Eisenstein, Michael, Kippin, Tod E, Plaxco, Kevin W, Soh, Hyongsok Tom

“…A sensor capable of continuously measuring specific molecules in the bloodstream in vivo would give clinicians a valuable window into patients' health and…”
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Reagentless, Structure-Switching, Electrochemical Aptamer-Based Sensors by Schoukroun-Barnes, Lauren R, Macazo, Florika C, Gutierrez, Brenda, Lottermoser, Justine, Liu, Juan, White, Ryan J

“…The development of structure-switching, electrochemical, aptamer-based sensors over the past ∼10 years has led to a variety of reagentless sensors capable of…”
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Optimization of Electrochemical Aptamer-Based Sensors via Optimization of Probe Packing Density and Surface Chemistry by White, Ryan J, Phares, Noelle, Lubin, Arica A, Xiao, Yi, Plaxco, Kevin W

“…Electrochemical, aptamer-based (E-AB) sensors, which are comprised of an electrode modified with surface immobilized, redox-tagged DNA aptamers, have emerged…”
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An Electrochemical Supersandwich Assay for Sensitive and Selective DNA Detection in Complex Matrices by Xia, Fan, White, Ryan J, Zuo, Xiaolei, Patterson, Adriana, Xiao, Yi, Kang, Di, Gong, Xiong, Plaxco, Kevin W, Heeger, Alan J

“…In a traditional sandwich assay, a DNA target hybridizes to a single copy of the signal probe. Here we employ a modified signal probe containing a methylene…”
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CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications by Rowe, Aaron A, Bonham, Andrew J, White, Ryan J, Zimmer, Michael P, Yadgar, Ramsin J, Hobza, Tony M, Honea, Jim W, Ben-Yaacov, Ilan, Plaxco, Kevin W

“…Although potentiostats are the foundation of modern electrochemical research, they have seen relatively little application in resource poor settings, such as…”
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Monitoring Charge Flux to Quantify Unusual Ligand-Induced Ion Channel Activity for Use in Biological Nanopore-Based Sensors by Macazo, Florika C, White, Ryan J

“…The utility of biological nanopores for the development of sensors has become a growing area of interest in analytical chemistry. Their emerging use in…”
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Quantitative Framework for Stochastic Nanopore Sensors Using Multiple Channels by Lazenby, Robert A, Macazo, Florika C, Wormsbecher, Richard F, White, Ryan J

“…Membrane protein channels employed as stochastic sensors offer large signal-to-noise ratios and high specificity in single molecule binding measurements…”
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Bench-Top Method for Fabricating Glass-Sealed Nanodisk Electrodes, Glass Nanopore Electrodes, and Glass Nanopore Membranes of Controlled Size by Zhang, Bo, Galusha, Jeremy, Shiozawa, Peter G, Wang, Gangli, Bergren, Adam Johan, Jones, Ronald M, White, Ryan J, Ervin, Eric N, Cauley, Chris C, White, Henry S

“…A simple benchtop method of fabricating glass-sealed nanometer-sized Au and Pt disk electrodes, glass nanopore electrodes, and glass nanopore membranes is…”
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Improving the Stability and Sensing of Electrochemical Biosensors by Employing Trithiol-Anchoring Groups in a Six-Carbon Self-Assembled Monolayer by Phares, Noelle, White, Ryan J, Plaxco, Kevin W

“…Alkane thiol self-assembled monolayers (SAMs) have seen widespread utility in the fabrication of electrochemical biosensors. Their utility, however, reflects a…”
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Perspective—Assessing Electrochemical, Aptamer-Based Sensors for Dynamic Monitoring of Cellular Signaling by Rousseau, Celeste R., Kumakli, Hope, White, Ryan J.

“…Electrochemical, aptamer-based (E-AB) sensors provide a generalizable strategy to quantitatively detect a variety of targets including small molecules and…”
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On the Signaling of Electrochemical Aptamer-Based Sensors: Collision- and Folding-Based Mechanisms by Xiao, Yi, Uzawa, Takanori, White, Ryan J., DeMartini, Daniel, Plaxco, Kevin W.

“…Recent years have seen the emergence of a new class of electrochemical sensors predicated on target binding‐induced folding of electrode‐bound redox‐modified…”
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Fluorescence Detection of Single-Nucleotide Polymorphisms with a Single, Self-Complementary, Triple-Stem DNA Probe by Xiao, Yi, Plakos, Kory J.I, Lou, Xinhui, White, Ryan J, Qian, Jiangrong, Plaxco, Kevin W, Soh, H. Tom

“…Singled out for its singularity: In a single-step, single-component, fluorescence-based method for the detection of single-nucleotide polymorphisms at room…”
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Rationally designing aptamer sequences with reduced affinity for controlled sensor performance by Schoukroun-Barnes, Lauren R, White, Ryan J

“…The relative ease of predicting the secondary structure of nucleic acid sequences lends itself to the design of sequences to perform desired functions. Here,…”
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Polarity-Switching Electrochemical Sensor for Specific Detection of Single-Nucleotide Mismatches by Hsieh, Kuangwen, White, Ryan J., Ferguson, Brian S., Plaxco, Kevin W., Xiao, Yi, Soh, H. Tom

“…Getting a response: A surface‐bound and redox‐modified (methylene blue) DNA probe architecture is at the heart of a sensor for detecting single‐nucleotide…”
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Sensitivity and Signal Complexity as a Function of the Number of Ion Channels in a Stochastic Sensor by Ervin, Eric N, White, Ryan J, White, Henry S

“…Alternating current, phase-sensitive stochastic detection using between 1 and 26 α-hemolysin ion channels reconstituted in a lipid bilayer, suspended over a…”
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