Search Results - "White, Robin E."

Astrocytes: targets for neuroprotection in stroke by Barreto, George, White, Robin E, Ouyang, Yibing, Xu, Lijun, Giffard, Rona G

“…In the past two decades, over 1000 clinical trials have failed to demonstrate a benefit in treating stroke, with the exception of thrombolytics. Although many…”
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miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo by Ouyang, Yi-Bing, Lu, Yu, Yue, Sibiao, Xu, Li-Jun, Xiong, Xiao-Xing, White, Robin E, Sun, Xiaoyun, Giffard, Rona G

“…Abstract MicroRNAs (miRNA) are short (~ 22 nt) single stranded RNAs that downregulate gene expression. Although recent studies indicate extensive miRNA changes…”
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What can the common fruit fly teach us about stroke?: lessons learned from the hypoxic tolerant Drosophila melanogaster by Quadros-Mennella, Princy S, Lucin, Kurt M, White, Robin E

“…Stroke, resulting in hypoxia and glucose deprivation, is a leading cause of death and disability worldwide. Presently, there are no treatments that reduce…”
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Corrigendum: What can the common fruit fly teach us about stroke?: lessons learned from the hypoxic tolerant Drosophila melanogaster by Quadros-Mennella, Princy S, Lucin, Kurt M, White, Robin E

“…[This corrects the article DOI: 10.3389/fncel.2024.1347980.]…”
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Regional heterogeneity in astrocyte responses following contusive spinal cord injury in mice by White, Robin E., McTigue, Dana M., Jakeman, Lyn B.

“…Astrocytes and their precursors respond to spinal cord injury (SCI) by proliferating, migrating, and altering phenotype. This contributes to glial scar…”
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Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse by Barreto, George E., White, Robin E., Xu, Lijun, Palm, Curtis J., Giffard, Rona G.

“…Astrocyte activation is a hallmark of the response to brain ischemia consisting of changes in gene expression and morphology. Heat shock protein 72 (Hsp72)…”
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IL-4 Is Required for Sex Differences in Vulnerability to Focal Ischemia in Mice by Xiong, Xiaoxing, Xu, Lijun, Wei, Liang, White, Robin E, Ouyang, Yi-Bing, Giffard, Rona G

“…BACKGROUND AND PURPOSE—Interleukin (IL)-4 protects from middle cerebral artery occlusion in male mice. Females generally show less injury in response to the…”
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The emerging roles of transplanted radial glial cells in regenerating the central nervous system by White, Robin E, Barry, Denis S

“…Scientists conclude that a combination of treatments involving rehabilitation,drug delivery,surgery and cell transplantation are necessary to achieve…”
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Mice lacking the β2 adrenergic receptor have a unique genetic profile before and after focal brain ischaemia by White, Robin E, Palm, Curtis, Xu, Lijun, Ling, Evelyn, Ginsburg, Mitchell, Daigle, Bernie J, Han, Ruquan, Patterson, Andrew, Altman, Russ B, Giffard, Rona G

“…The role of the β2AR (β2 adrenergic receptor) after stroke is unclear as pharmacological manipulations of the β2AR have produced contradictory results. We…”
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MicroRNA-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin by Stary, Creed M, Xu, Lijun, Sun, Xiaoyun, Ouyang, Yi-Bing, White, Robin E, Leong, Jason, Li, John, Xiong, Xiaoxing, Giffard, Rona G

“…BACKGROUND AND PURPOSE—MicroRNA (miR)-200c increases rapidly in the brain after transient cerebral ischemia but its role in poststroke brain injury is unclear…”
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The use of microRNAs to modulate redox and immune response to stroke by Ouyang, Yi-Bing, Stary, Creed M, White, Robin E, Giffard, Rona G

“…Cerebral ischemia is a major cause of death and disability throughout the world, yet therapeutic options remain limited. The interplay between the cellular…”
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Beclin 1 regulates astrocyte phagocytosis and phagosomal recruitment of retromer by Lemus Silva, Evelyn G., Delgadillo, Yuberki, White, Robin E., Lucin, Kurt M.

“…Phagocytosis plays an important role in maintaining brain homeostasis and when impaired can result in the accumulation of unwanted cellular material. While…”
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MicroRNA-320 induces neurite outgrowth by targeting ARPP-1 by White, Robin E, Giffard, Rona G

“…MicroRNAs are important in the development, functioning, and pathophysiology of the central nervous system. Here, we show that increasing the levels of…”
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Mitigation of Murine Focal Cerebral Ischemia by the Hypocretin/Orexin System is Associated With Reduced Inflammation by XIAOXING XIONG, WHITE, Robin E, LIJUN XU, LIYA YANG, XIAOYUN SUN, BENDE ZOU, PASCUAL, Conrado, SAKURAI, Takeshi, GIFFARD, Rona G, XIE, Xinmin (simon)

“…Brain ischemia causes immediate and delayed cell death that is exacerbated by inflammation. Recent studies show that hypocretin-1/orexin-A (Hcrt-1) reduces…”
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Don't fence me in: harnessing the beneficial roles of astrocytes for spinal cord repair by White, Robin E, Jakeman, Lyn B

“…Astrocytes comprise a heterogeneous cell population that plays a complex role in repair after spinal cord injury. Reactive astrocytes are major contributors to…”
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Transforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injury by White, Robin E, Rao, Meghan, Gensel, John C, McTigue, Dana M, Kaspar, Brian K, Jakeman, Lyn B

“…Astrocytes are both detrimental and beneficial for repair and recovery after spinal cord injury (SCI). These dynamic cells are primary contributors to the…”
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TGF-α increases astrocyte invasion and promotes axonal growth into the lesion following spinal cord injury in mice by White, Robin E., Yin, Feng Qin, Jakeman, Lyn B.

“…Astrocytes respond to environmental cues and play a multifaceted role in the response to trauma in the central nervous system. As the most prevalent…”
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MicroRNA-320 induces neurite outgrowth by targeting ARPP-1 by WHITE, Robin E, GIFFARD, Rona G

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Mice lacking the beta 2 adrenergic receptor have a unique genetic profile before and after focal brain ischaemia by White, Robin E, Palm, Curtis, Xu, Lijun, Ling, Evelyn, Ginsburg, Mitchell, Daigle, Bernie J, Han, Ruquan, Patterson, Andrew, Altman, Russ B, Giffard, Rona G

“…The role of the beta 2AR ( beta 2 adrenergic receptor) after stroke is unclear as pharmacological manipulations of the beta 2AR have produced contradictory…”
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miR-200c Contributes to Injury From Transient Focal Cerebral Ischemia by Targeting Reelin by Stary, Creed M., Xu, Lijun, Sun, Xiaoyun, Ouyang, Yi-Bing, White, Robin E., Leong, Jason, Li, John, Xiong, Xiaoxing, Giffard, Rona G.

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