Search Results - "White, Rebekah R"

Aptamers as Therapeutics by Nimjee, Shahid M, White, Rebekah R, Becker, Richard C, Sullenger, Bruce A

“…Aptamers are single-stranded nucleic acid molecules that bind to and inhibit proteins and are commonly produced by systematic evolution of ligands by…”
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Notch Promotes Radioresistance of Glioma Stem Cells by Wang, Jialiang, Wakeman, Timothy P., Lathia, Justin D., Hjelmeland, Anita B., Wang, Xiao‐Fan, White, Rebekah R., Rich, Jeremy N., Sullenger, Bruce A.

“…Radiotherapy represents the most effective nonsurgical treatments for gliomas. However, gliomas are highly radioresistant and recurrence is nearly universal…”
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Aptamers for Targeted Drug Delivery by Ray, Partha, White, Rebekah R

“…Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically…”
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Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy by Auer, Rebecca C., White, Rebekah R., Kemeny, Nancy E., Schwartz, Lawrence H., Shia, Jinru, Blumgart, Leslie H., DeMatteo, Ronald P., Fong, Yuman, Jarnagin, William R., D'Angelica, Michael I.

“…BACKGROUND: During chemotherapy, some colorectal liver metastases (LMs) disappear on serial imaging. This disappearance may represent a complete response (CR)…”
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Crystal structure of an RNA aptamer bound to thrombin by Long, Stephen B, Long, Meredith B, White, Rebekah R, Sullenger, Bruce A

“…Aptamers, an emerging class of therapeutics, are DNA or RNA molecules that are selected to bind molecular targets that range from small organic compounds to…”
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The Impact of Vascular Resection on Early Postoperative Outcomes after Pancreaticoduodenectomy: An Analysis of the American College of Surgeons National Surgical Quality Improvement Program Database by Castleberry, Anthony W., White, Rebekah R., De La Fuente, Sebastian G., Clary, Bryan M., Blazer, Dan G., McCann, Richard L., Pappas, Theodore N., Tyler, Douglas S., Scarborough, John E.

“…Background Several single-center reports suggest that vascular resection (VR) during pancreaticoduodenectomy (PD) for patients with pancreatic adenocarcinoma…”
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Local ablative therapies and the effect on antitumor immune responses in pancreatic cancer – A review by Erdem, Suna, Narayanan, Jayanth Shankara, Worni, Mathias, Bolli, Martin, White, Rebekah R.

“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease, projected to rank as the second most prevalent cause of cancer-related mortality by 2030…”
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Examining Reoperation and Readmission after Hepatic Surgery by Barbas, Andrew S., MD, Turley, Ryan S., MD, Mallipeddi, Mohan K., MD, Lidsky, Michael E., MD, Reddy, Srinevas K., MD, White, Rebekah R., MD, FACS, Clary, Bryan M., MD, FACS

“…Background Although the perioperative mortality from hepatic resection has improved considerably, this procedure is still associated with substantial morbidity…”
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Cell-SELEX Identifies a “Sticky” RNA Aptamer Sequence by Ray, Partha, White, Rebekah R.

“…Cell-SELEX is performed to select for cell binding aptamers. We employed an additional selection pressure by using RNAse to remove surface-binding aptamers and…”
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Optimizing Patient Selection for Irreversible Electroporation of Locally Advanced Pancreatic Cancer: Analyses of Survival by Woeste, Matthew R, Wilson, Khaleel D, Kruse, Edward J, Weiss, Matthew J, Christein, John D, White, Rebekah R, Martin, 2nd, Robert C G

“…Irreversible electroporation (IRE) has emerged as a viable consolidative therapy after induction chemotherapy, in which this combination has improved overall…”
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Work-Life Integration for Academic Surgeons by White, Rebekah R

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In Vivo Selection Against Human Colorectal Cancer Xenografts Identifies an Aptamer That Targets RNA Helicase Protein DHX9 by Mi, Jing, Ray, Partha, Liu, Jenny, Kuan, Chien-Tsun, Xu, Jennifer, Hsu, David, Sullenger, Bruce A, White, Rebekah R, Clary, Bryan M

“…The ability to selectively target disease-related tissues with molecules is critical to the design of effective therapeutic and diagnostic reagents…”
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Targeting eNOS in Pancreatic Cancer by LAMPSON, Benjamin L, DISEAN KENDALL, S, CARDONA, Diana M, COUNTER, Christopher M, ANCRILE, Brooke B, MORRISON, Meghan M, SHEALY, Michael J, BARRIENTOS, Katharine S, CROWE, Matthew S, KASHATUS, David F, WHITE, Rebekah R, GURLEY, Susan B

“…Mortality from pancreatic ductal adenocarcinoma cancer (PDAC) is among the highest of any cancer and frontline therapy has changed little in years. Activation…”
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Antidote-mediated control of an anticoagulant aptamer in vivo by Rusconi, Christopher P, Sullenger, Bruce A, Roberts, Joseph D, Pitoc, George A, Nimjee, Shahid M, White, Rebekah R, Quick, George, Scardino, Elizabeth, Fay, William P

“…Patient safety and treatment outcome could be improved if physicians could rapidly control the activity of therapeutic agents in their patients. Antidote…”
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A standardized care plan is associated with shorter hospital length of stay in patients undergoing pancreaticoduodenectomy by Nussbaum, Daniel P., MD, Penne, Kara, MSN, Stinnett, Sandra S., MD, Speicher, Paul J., MD, Cocieru, Andrei, MD, Blazer, Dan G., MD, Zani, Sabino, MD, Clary, Bryan M., MD, Tyler, Douglas S., MD, White, Rebekah R., MD

“…Abstract Background In this retrospective review, we evaluate a standardized care plan (SCP) for patients undergoing pancreaticoduodenectomy, which included…”
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Comparison of Outcomes and the Use of Multimodality Therapy in Young and Elderly People Undergoing Surgical Resection of Pancreatic Cancer by Barbas, Andrew S., Turley, Ryan S., Ceppa, Eugene P., Reddy, Srinevas K., Blazer III, Dan G., Clary, Bryan M., Pappas, Theodore N., Tyler, Douglas S., White, Rebekah R., Lagoo, Sandhya A.

“…Objectives To compare outcomes and the use of multimodality therapy in young and elderly people with pancreatic cancer undergoing surgical resection. Design…”
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Hepatic Resection for Hepatocellular Carcinoma: Do Contemporary Morbidity and Mortality Rates Demand a Transition to Ablation as First-Line Treatment? by Li, George Z., BS, Speicher, Paul J., MD, Lidsky, Michael E., MD, Darrabie, Marcus D., MD, Scarborough, John E., MD, FACS, White, Rebekah R., MD, FACS, Turley, Ryan S., MD, Clary, Bryan M., MD, FACS

“…Background Despite the rising incidence of hepatocellular carcinoma (HCC), challenges and controversy persist in optimizing treatment. As recent randomized…”
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Neoadjuvant Chemotherapy for Localized Pancreatic Cancer: Too Little or Too Long? by White, Rebekah R., Evans, Douglas B.

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Pancreatic Neuroendocrine Tumors: Selection, Selection, Selection by White, Rebekah R., M.D

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A Decision Model of Therapy for Potentially Resectable Pancreatic Cancer by VanHouten, Jacob P., B.A, White, Rebekah R., M.D, Jackson, Gretchen Purcell, M.D., Ph.D

“…Background Optimal treatment for potentially resectable pancreatic cancer is controversial. Resection is considered the only curative treatment, but…”
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