Search Results - "White, Paul J."

Continued preference for suboptimal habitat reduces bat survival with white-nose syndrome by Hopkins, Skylar R., Hoyt, Joseph R., White, J. Paul, Kaarakka, Heather M., Redell, Jennifer A., DePue, John E., Scullon, William H., Kilpatrick, A. Marm, Langwig, Kate E.

“…Habitat alteration can influence suitability, creating ecological traps where habitat preference and fitness are mismatched. Despite their importance,…”
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Effect of torpor on host transcriptomic responses to a fungal pathogen in hibernating bats by Field, Kenneth A., Sewall, Brent J., Prokkola, Jenni M., Turner, Gregory G., Gagnon, Marianne F., Lilley, Thomas M., Paul White, J., Johnson, Joseph S., Hauer, Christopher L., Reeder, DeeAnn M.

“…Hibernation, the use of prolonged torpor to depress metabolism, is employed by mammals to conserve resources during extended periods of extreme temperatures…”
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New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism by Vecchio, Elizabeth A, Baltos, Jo‐Anne, Nguyen, Anh T N, Christopoulos, Arthur, White, Paul J, May, Lauren T

“…Adenosine receptors are a family of GPCRs containing four subtypes (A1, A2A, A2B and A3 receptors), all of which bind the ubiquitous nucleoside adenosine…”
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Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus) by Rocke, Tonie E., Kingstad-Bakke, Brock, Wüthrich, Marcel, Stading, Ben, Abbott, Rachel C., Isidoro-Ayza, Marcos, Dobson, Hannah E., dos Santos Dias, Lucas, Galles, Kevin, Lankton, Julia S., Falendysz, Elizabeth A., Lorch, Jeffrey M., Fites, J. Scott, Lopera-Madrid, Jaime, White, J. Paul, Klein, Bruce, Osorio, Jorge E.

“…White-nose syndrome (WNS) caused by the fungus, Pseudogymnoascus destructans ( Pd ) has killed millions of North American hibernating bats. Currently, methods…”
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Environmental reservoir dynamics predict global infection patterns and population impacts for the fungal disease white-nose syndrome by Hoyt, Joseph R., Langwig, Kate E., Sun, Keping, Parise, Katy L., Li, Aoqiang, Wang, Yujuan, Huang, Xiaobin, Worledge, Lisa, Miller, Helen, White, J. Paul, Kaarakka, Heather M., Redell, Jennifer A., Görföl, Tamás, Boldogh, Sándor András, Fukui, Dai, Sakuyama, Muneki, Yachimori, Syuuji, Sato, Akiyoshi, Dalannast, Munkhnast, Jargalsaikhan, Ariunbold, Batbayar, Nyambayar, Yovelo, Yossi, Amichaio, Eran, Natradze, Ioseb, Frick, Winifred F., Foster, Jeffrey T., Feng, Jiang, Kilpatrick, A. Marm

“…Disease outbreaks and pathogen introductions can have significant effects on host populations, and the ability of pathogens to persist in the environment can…”
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Field trial of a probiotic bacteria to protect bats from white-nose syndrome by Hoyt, Joseph R., Langwig, Kate E., White, J. Paul, Kaarakka, Heather M., Redell, Jennifer A., Parise, Katy L., Frick, Winifred F., Foster, Jeffrey T., Kilpatrick, A. Marm

“…Tools for reducing wildlife disease impacts are needed to conserve biodiversity. White-nose syndrome (WNS), caused by the fungus Pseudogymnoascus destructans ,…”
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Development of a self-report instrument for measuring in-class student engagement reveals that pretending to engage is a significant unrecognized problem by Fuller, Kathryn A, Karunaratne, Nilushi S, Naidu, Som, Exintaris, Betty, Short, Jennifer L, Wolcott, Michael D, Singleton, Scott, White, Paul J

“…Student engagement during classes includes behavioural, cognitive and emotional components, and is a pre-requisite for successful active learning environments…”
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Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist by Valant, Celine, May, Lauren T., Aurelio, Luigi, Chuo, Chung Hui, White, Paul J., Baltos, Jo-Anne, Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur

“…The concepts of allosteric modulation and biased agonism are revolutionizing modern approaches to drug discovery, particularly in the field of G…”
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Cryptic connections illuminate pathogen transmission within community networks by Hoyt, Joseph R., Langwig, Kate E., White, J. Paul, Kaarakka, Heather M., Redell, Jennifer A., Kurta, Allen, DePue, John E., Scullon, William H., Parise, Katy L., Foster, Jeffrey T., Frick, Winifred F., Kilpatrick, A. Marm

“…Understanding host interactions that lead to pathogen transmission is fundamental to the prediction and control of epidemics 1 – 5 . Although the majority of…”
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Targeting Adenosine Receptors for the Treatment of Cardiac Fibrosis by Vecchio, Elizabeth A, White, Paul J, May, Lauren T

“…Adenosine is a ubiquitous molecule with key regulatory and cytoprotective mechanisms at times of metabolic imbalance in the body. Among a plethora of…”
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BARRIERS TO SUCCESSFUL DELIVERY OF SHORT INTERFERING RNA AFTER SYSTEMIC ADMINISTRATION by White, Paul J

“…SUMMARY 1 RNA interference in vivo has tremendous potential, both with respect to the elucidation of protein function in animals and as a therapeutic platform…”
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Incidence and taxonomic richness of mosquitoes in the diets of little brown and big brown bats by Wray, Amy K., Jusino, Michelle A., Banik, Mark T., Palmer, Jonathan M., Kaarakka, Heather, White, J. Paul, Lindner, Daniel L., Gratton, Claudio, Peery, M. Zachariah

“…Bats have been portrayed as important consumers of mosquitoes, but evidence supporting this claim is surprisingly scant. We collected the fecal material of 2…”
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Environmental transmission of Pseudogymnoascus destructans to hibernating little brown bats by Hicks, Alan C., Darling, Scott R., Flewelling, Joel E., von Linden, Ryan, Meteyer, Carol U., Redell, David N., White, J. Paul, Redell, Jennifer, Smith, Ryan, Blehert, David S., Rayman-Metcalf, Noelle L., Hoyt, Joseph R., Okoniewski, Joseph C., Langwig, Kate E.

“…Pathogens with persistent environmental stages can have devastating effects on wildlife communities. White-nose syndrome (WNS), caused by the fungus…”
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Flipped Classroom Implementation: A Case Report of Two Higher Education Institutions in the United States and Australia by McLaughlin, Jacqueline E., White, Paul J., Khanova, Julia, Yuriev, Elizabeth

“…This case report explored the implementation of flipped classrooms at two higher education institutions. Experiences and publications from the institutions…”
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Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution by Ho, Joan K., White, Paul J., Pouton, Colin W.

“…Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA…”
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Adopting an active learning approach to teaching in a research-intensive higher education context transformed staff teaching attitudes and behaviours by White, Paul J., Larson, Ian, Styles, Kim, Yuriev, Elizabeth, Evans, Darrell R., Rangachari, P.K., Short, Jennifer L., Exintaris, Betty, Malone, Daniel T., Davie, Briana, Eise, Nicole, Mc Namara, Kevin, Naidu, Somaiya

“…The conventional lecture has significant limitations in the higher education context, often leading to a passive learning experience for students. This paper…”
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Longevity Records of Five Male Little Brown Bats (Myotis lucifugus) in Northwest Wisconsin by White, J. Paul, Nordquist, Gerda E, Kaarakka, Heather M

“…Although bats are highly transient and secretive animals, banding allows biologists to track the longevity of these mammals and their return rates to various…”
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Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure by Rueda, Patricia, Merlin, Jon, Chimenti, Stefano, Feletou, Michel, Paysant, Jerome, White, Paul J, Christopoulos, Arthur, Sexton, Patrick M, Summers, Roger J, Charman, William N, May, Lauren T, Langmead, Christopher J

“…Adenosine A receptors (A R) are a potential target for cardiac injury treatment due to their cardioprotective/antihypertrophic actions, but drug development…”
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THE FUNGUS TRICHOPHYTON REDELLII SP. NOV. CAUSES SKIN INFECTIONS THAT RESEMBLE WHITE-NOSE SYNDROME OF HIBERNATING BATS by Lorch, Jeffrey M., Minnis, Andrew M., Meteyer, Carol U., Redell, Jennifer A., White, J. Paul, Kaarakka, Heather M., Muller, Laura K., Lindner, Daniel L., Verant, Michelle L., Shearn-Bochsler, Valerie, Blehert, David S.

“…Before the discovery of white-nose syndrome (WNS), a fungal disease caused by Pseudogymnoascus destructans, there were no reports of fungal skin infections in…”
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Enhanced Extravasation, Stability and in Vivo Cardiac Gene Silencing via in Situ siRNA–Albumin Conjugation by Lau, Shannen, Graham, Bim, Cao, Nga, Boyd, Ben J, Pouton, Colin W, White, Paul J

“…A potential barrier to progression of siRNA therapeutics to the clinic is the ability of these agents to cross the vascular endothelium to reach target cells…”
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