Search Results - "White, Mark P."

Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency by Theodoris, Christina V., Li, Molong, White, Mark P., Liu, Lei, He, Daniel, Pollard, Katherine S., Bruneau, Benoit G., Srivastava, Deepak

“…The mechanisms by which transcription factor haploinsufficiency alters the epigenetic and transcriptional landscape in human cells to cause disease are…”
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miR-145 and miR-143 regulate smooth muscle cell fate and plasticity by Srivastava, Deepak, Cordes, Kimberly R, Sheehy, Neil T, White, Mark P, Berry, Emily C, Morton, Sarah U, Muth, Alecia N, Lee, Ting-Hein, Miano, Joseph M, Ivey, Kathryn N

“…MicroRNAs (miRNAs) are regulators of myriad cellular events, but evidence for a single miRNA that can efficiently differentiate multipotent stem cells into a…”
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Derivation Conditions Impact X-Inactivation Status in Female Human Induced Pluripotent Stem Cells by Tomoda, Kiichiro, Takahashi, Kazutoshi, Leung, Karen, Okada, Aki, Narita, Megumi, Yamada, N. Alice, Eilertson, Kirsten E., Tsang, Peter, Baba, Shiro, White, Mark P., Sami, Salma, Srivastava, Deepak, Conklin, Bruce R., Panning, Barbara, Yamanaka, Shinya

“…Female human induced pluripotent stem cell (hiPSC) lines exhibit variability in X-inactivation status. The majority of hiPSC lines maintain one…”
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Limited Gene Expression Variation in Human Embryonic Stem Cell and Induced Pluripotent Stem Cell‐Derived Endothelial Cells by White, Mark P., Rufaihah, Abdul J., Liu, Lei, Ghebremariam, Yohannes T., Ivey, Kathryn N., Cooke, John P., Srivastava, Deepak

“…Recent evidence suggests human embryonic stem cell (hESC) and induced pluripotent stem (iPS) cell lines have differences in their epigenetic marks and…”
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MicroRNA-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting Vascular Endothelial Growth Factor Signaling by Hassel, David, Cheng, Paul, White, Mark P, Ivey, Kathryn N, Kroll, Jens, Augustin, Hellmut G, Katus, Hugo A, Stainier, Didier Y.R, Srivastava, Deepak

“…RATIONALE:Formation and remodeling of the vasculature during development and disease involve a highly conserved and precisely regulated network of attractants…”
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The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch by Sheehy, Neil T, Cordes, Kimberly R, White, Mark P, Ivey, Kathryn N, Srivastava, Deepak

“…Neural crest cells (NCCs) are a subset of multipotent, migratory stem cells that populate a large number of tissues during development and are important for…”
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The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling by Barruet, Emilie, Morales, Blanca M, Lwin, Wint, White, Mark P, Theodoris, Christina V, Kim, Hannah, Urrutia, Ashley, Wong, Sarah Anne, Srivastava, Deepak, Hsiao, Edward C

“…The Activin A and bone morphogenetic protein (BMP) pathways are critical regulators of the immune system and of bone formation. Inappropriate activation of…”
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NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium by White, Mark P, Theodoris, Christina V, Liu, Lei, Collins, William J, Blue, Kathleen W, Lee, Joon Ho, Meng, Xianzhong, Robbins, Robert C, Ivey, Kathryn N, Srivastava, Deepak

“…Abstract Valvular and vascular calcification are common causes of cardiovascular morbidity and mortality. Developing effective treatments requires…”
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Compounds that confer thermal stress resistance and extended lifespan by Benedetti, Michael G., Foster, Amanda L., Vantipalli, Maithili C., White, Mark P., Sampayo, James N., Gill, Matthew S., Olsen, Anders, Lithgow, Gordon J.

“…The observation that long-lived and relatively healthy animals can be obtained by simple genetic manipulation prompts the search for chemical compounds that…”
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DAF‐12‐dependent rescue of dauer formation in Caenorhabditis elegans by (25S)‐cholestenoic acid by Held, Jason M., White, Mark P., Fisher, Alfred L., Gibson, Bradford W., Lithgow, Gordon J., Gill, Matthew S.

“…Summary Population density, temperature and food availability all regulate the formation of the Caenorhabditis elegans dauer larva by modulating endocrine…”
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Proteomic identification of processes and pathways characteristic of osmoregulatory tissues in spiny dogfish shark ( Squalus acanthias) by Lee, Jinoo, Valkova, Nelly, White, Mark P., Kültz, Dietmar

“…We used dogfish shark ( Squalus acanthias) as a model for proteome analysis of six different tissues to evaluate tissue-specific protein expression on a global…”
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Abstract 18010: Induced Pluripotent Stem Cell-Based Modeling of Human NOTCH1 Mutations Reveals Novel Pathways Regulating Aortic Valve Disease by Theodoris, Christina V, White, Mark P, Li, Molong, Liu, Lei, He, Daniel, Pollard, Katherine S, Bruneau, Benoit G, Srivastava, Deepak

“…Abstract only In humans, NOTCH1 mutations result in congenital heart defects including valve malformations and severe valve calcification in adults. Valve…”
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miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling by Hassel, David, Cheng, Paul, White, Mark P., Ivey, Kathryn N., Kroll, Jens, Augustin, Hellmut G., Katus, Hugo A., Stainier, Didier Y.R., Srivastava, Deepak

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Derivation Conditions Determine X-Reactivation Status in Female Human Induced Pluripotent Stem Cells by Tomoda, Kiichiro, Takahashi, Kazutoshi, Leung, Karen, Okada, Aki, Narita, Megumi, Yamada, N. Alice, Eilertson, Kirsten E., Tsang, Peter, Baba, Shiro, White, Mark P., Sami, Salma, Srivastava, Deepak, Conklin, Bruce R., Panning, Barbara, Yamanaka, Shinya

“…Female human induced pluripotent stem cell (hiPSC) lines exhibit variability in X-inactivation status. The majority of hiPSC lines maintain one…”
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The Role of NOTCH1 Signaling in Aortic Valve Disease by White, Mark P

“…Calcification of the aortic valve is a common disease affecting many people, and requires invasive valve replacement surgery to prevent irreparable damage to…”
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The Role of NOTCH1 Signaling in Aortic Valve Disease by White, Mark P

“…Calcification of the aortic valve is a common disease affecting many people, and requires invasive valve replacement surgery to prevent irreparable damage to…”
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Consider Microfiltration and Ultrafiltration Membranes for Water Treatment by Mark White, PE

“…Microfiltration and ultrafiltration have gained rapid acceptance as processes that provide reliable and high-level particle, turbidity, and microorganism…”
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