Search Results - "White, M M"
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Adding Aliphatic C-H Bond Oxidations to Synthesis
Published in Science (American Association for the Advancement of Science) (17-02-2012)“…Oxidations of aliphatic C–H bonds, known since the 1800s, have only recently been considered for use in organic synthesis. Aliphatic C–H bonds are among the…”
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Aliphatic C–H Oxidations for Late-Stage Functionalization
Published in Journal of the American Chemical Society (31-10-2018)“…The atomistic change of C(sp3 )–H to C(sp3 )–O can have a profound impact on the physical and biological properties of small molecules. Traditionally,…”
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Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2
Published in Diabetologia (01-10-2012)“…The insulin receptor substrate proteins IRS1 and IRS2 are key targets of the insulin receptor tyrosine kinase and are required for hormonal control of…”
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A manganese catalyst for highly reactive yet chemoselective intramolecular C(sp3)–H amination
Published in Nature chemistry (01-12-2015)“…C–H bond oxidation reactions underscore the existing paradigm wherein high reactivity and high selectivity are inversely correlated. The development of…”
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C–H to C–N Cross-Coupling of Sulfonamides with Olefins
Published in Journal of the American Chemical Society (07-03-2018)“…Cross-coupling of nitrogen with hydrocarbons under fragment coupling conditions stands to significantly impact chemical synthesis. Herein, we disclose a…”
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Optofluidic microsystems for chemical and biological analysis
Published in Nature photonics (01-10-2011)“…Optofluidics — the synergistic integration of photonics and microfluidics — is a new analytical field that provides a number of unique characteristics for…”
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Manganese-catalysed benzylic C(sp3)–H amination for late-stage functionalization
Published in Nature chemistry (01-06-2018)“…Reactions that directly install nitrogen into C – H bonds of complex molecules are significant because of their potential to change the chemical and biological…”
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Fusion of Enveloped Viruses in Endosomes
Published in Traffic (Copenhagen, Denmark) (01-06-2016)“…To initiate infection, enveloped viruses must fuse with a cell membrane, a process mediated by a dedicated viral fusion protein. To date, these proteins group…”
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A critical review of flexible and porous SERS sensors for analytical chemistry at the point-of-sample
Published in Analytica chimica acta (04-07-2019)“…For decades surface enhanced Raman spectroscopy (SERS) has been intensely investigated as a possible solution for performing analytical chemistry at the point…”
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Total synthesis and study of 6-deoxyerythronolide B by late-stage C–H oxidation
Published in Nature chemistry (01-10-2009)“…Among the frontier challenges in chemistry in the twenty-first century are the interconnected goals of increasing synthetic efficiency and diversity in the…”
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Combined Effects on Selectivity in Fe-Catalyzed Methylene Oxidation
Published in Science (American Association for the Advancement of Science) (29-01-2010)“…Methylene C-H bonds are among the most difficult chemical bonds to selectively functionalize because of their abundance in organic structures and inertness to…”
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Catalyst-Controlled Aliphatic C–H Oxidations with a Predictive Model for Site-Selectivity
Published in Journal of the American Chemical Society (25-09-2013)“…Selective aliphatic C-H bond oxidations may have a profound impact on synthesis because these bonds exist across all classes of organic molecules. Central to…”
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Iron-Catalyzed Intramolecular Allylic C–H Amination
Published in Journal of the American Chemical Society (01-02-2012)“…A highly selective C–H amination reaction under iron catalysis has been developed. This novel system, which employs an inexpensive, nontoxic [FeIIIPc] catalyst…”
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Transgender stigma and health: A critical review of stigma determinants, mechanisms, and interventions
Published in Social science & medicine (1982) (01-12-2015)“…Transgender people in the United States experience widespread prejudice, discrimination, violence, and other forms of stigma. This critical review aims to…”
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COVID-SCORE: A global survey to assess public perceptions of government responses to COVID-19 (COVID-SCORE-10)
Published in PloS one (06-10-2020)“…Understanding public perceptions of government responses to COVID-19 may foster improved public cooperation. Trust in government and population risk of…”
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On the performance quantification of resonant refractive index sensors
Published in Optics express (21-01-2008)“…Refractive index (RI) sensors based on optical resonance techniques are receiving a high degree of attention because of the need to develop simple, low-cost,…”
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Oceanic Island Basalts and Mantle Plumes: The Geochemical Perspective
Published in Annual review of earth and planetary sciences (01-01-2010)“…Mantle plumes—which are usually, but not always, chemically distinct from the mid-ocean ridge basalt (MORB)—may be rooted in the core-mantle boundary and begin…”
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IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity
Published in Diabetes, obesity & metabolism (01-09-2014)“…Understanding how metabolism and nutrient homeostasis integrates with life span and neurodegeneration is a complicated undertaking. Important inconsistencies…”
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Revisiting COVID-19 vaccine hesitancy around the world using data from 23 countries in 2021
Published in Nature communications (01-07-2022)“…The COVID-19 pandemic continues to impact daily life, including health system operations, despite the availability of vaccines that are effective in greatly…”
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