Search Results - "White, Iain R"
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Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
Published in Nature communications (05-11-2019)“…Global ageing poses a substantial economic burden on health and social care costs. Enabling a greater proportion of older people to stay healthy for longer is…”
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2
Breath and plasma metabolomics to assess inflammation in acute stroke
Published in Scientific reports (09-11-2021)“…Inflammation is strongly implicated in both injury and repair processes occurring after stroke. In this exploratory study we assessed the feasibility of…”
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3
Metabolite profiling of the ripening of Mangoes Mangifera indica L. cv. ‘Tommy Atkins’ by real-time measurement of volatile organic compounds
Published in Metabolomics (01-03-2016)“…Real-time profiling of mango ripening based on proton transfer reaction-time of flight-mass spectrometry (PTR–ToF–MS) of small molecular weight volatile…”
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4
Increased Sensitivity in Proton Transfer Reaction Mass Spectrometry by Incorporation of a Radio Frequency Ion Funnel
Published in Analytical chemistry (Washington) (19-06-2012)“…A drift tube capable of simultaneously functioning as an ion funnel is demonstrated in proton transfer reaction mass spectrometry (PTR-MS) for the first time…”
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5
Observations of the Release of Non-methane Hydrocarbons from Fractured Shale
Published in Environmental science & technology (05-08-2014)“…The organic content of shale has become of commercial interest as a source of hydrocarbons, owing to the development of hydraulic fracturing (“fracking”)…”
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6
What effect does VOC sampling time have on derived OH reactivity?
Published in Atmospheric chemistry and physics (24-05-2016)“…State-of-the-art techniques allow for rapid measurements of total OH reactivity. Unknown sinks of OH and oxidation processes in the atmosphere have been…”
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7
Circadian rhythm of exhaled biomarkers in health and asthma
Published in The European respiratory journal (01-10-2019)“…Circadian rhythms regulate and reflect many biological processes. Investigating circadian variability in biomarkers is important since the diurnal variability…”
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Microbial Volatiles as Diagnostic Biomarkers of Bacterial Lung Infection in Mechanically Ventilated Patients
Published in Clinical infectious diseases (21-03-2023)“…Abstract Background Early and accurate recognition of respiratory pathogens is crucial to prevent increased risk of mortality in critically ill patients…”
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Composition and diversity analysis of the lung microbiome in patients with suspected ventilator-associated pneumonia
Published in Critical care (London, England) (06-07-2022)“…Background Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis of airway…”
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Detection and quantification of exhaled volatile organic compounds in mechanically ventilated patients - comparison of two sampling methods
Published in Analyst (London) (04-01-2021)“…Exhaled breath analysis is a promising new diagnostic tool, but currently no standardised method for sampling is available in mechanically ventilated patients…”
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11
Validation of an assay for the determination of levoglucosan and associated monosaccharide anhydrides for the quantification of wood smoke in atmospheric aerosol
Published in Analytical and bioanalytical chemistry (01-09-2014)“…Biomass burning is becoming an increasing contributor to atmospheric particulate matter, and concern is increasing over the detrimental health effects of…”
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Headspace volatile organic compounds from bacteria implicated in ventilator-associated pneumonia analysed by TD-GC/MS
Published in Journal of breath research (01-04-2018)“…Ventilator-associated pneumonia (VAP) is a healthcare-acquired infection arising from the invasion of the lower respiratory tract by opportunistic pathogens in…”
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Untargeted Molecular Analysis of Exhaled Breath as a Diagnostic Test for Ventilator-Associated Lower Respiratory Tract Infections (BreathDx)
Published in Thorax (01-01-2022)“…Patients suspected of ventilator-associated lower respiratory tract infections (VA-LRTIs) commonly receive broad-spectrum antimicrobial therapy unnecessarily…”
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14
Development of an adaptable headspace sampling method for metabolic profiling of the fungal volatome
Published in Analyst (London) (07-09-2018)“…Pulmonary aspergillosis can cause serious complications in people with a suppressed immune system. Volatile metabolites emitted by Aspergillus spp. have shown…”
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TD/GC–MS analysis of volatile markers emitted from mono- and co-cultures of Enterobacter cloacae and Pseudomonas aeruginosa in artificial sputum
Published in Metabolomics (01-05-2018)“…Introduction Infections such as ventilator-associated pneumonia (VAP) can be caused by one or more pathogens. Current methods for identifying these pathogenic…”
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Use of Reactive Tracers To Determine Ambient OH Radical Concentrations: Application within the Indoor Environment
Published in Environmental science & technology (15-08-2010)“…The hydroxyl radical (OH) plays a key role in determining indoor air quality. However, its highly reactive nature and low concentration indoors impede direct…”
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DISPERSION EXPERIMENTS IN CENTRAL LONDON: The 2007 DAPPLE Project
Published in Bulletin of the American Meteorological Society (01-07-2009)“…In the event of a release of toxic gas in the center of London, emergency services personnel would need to determine quickly the extent of the area…”
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Real-time multi-marker measurement of organic compounds in human breath: towards fingerprinting breath
Published in Journal of breath research (01-03-2013)“…The prospects for exploiting proton transfer reaction-time of flight-mass spectrometry (PTR-ToF-MS) in medical diagnostics are illustrated through a series of…”
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An estimation of the global emission of methyl bromide from rapeseed ( Brassica napus) from 1961 to 2003
Published in Atmospheric environment (1994) (2008)“…Gan et al. [Gan, J., Yates, S.R., Ohr, H.D., Sims, J.J., 1998. Production of methyl bromide by terrestrial higher plants. Geophysical Research Letters 25 (19),…”
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Exhaled volatile organic compounds and respiratory disease: Recent progress and future outlook
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-07-2024)“…The theoretical basis of eVOCs as biomarkers for respiratory disease diagnosis is described, followed by a review of the potential biomarkers that have been…”
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