Search Results - "White, Elizabeth J F"
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PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
Published in Nature communications (04-11-2014)“…Post-transcriptional gene regulation is robustly regulated by RNA-binding proteins (RBPs). Here we describe the collection of RNAs regulated by AUF1…”
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Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation
Published in Biochimica et biophysica acta (01-06-2013)“…AUF1 is a family of four proteins generated by alternative pre-mRNA splicing that form high affinity complexes with AU-rich, mRNA-destabilizing sequences…”
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AUF1 regulation of coding and noncoding RNA
Published in Wiley interdisciplinary reviews. RNA (01-03-2017)“…AUF1 is a family of four RNA‐binding proteins (RBPs) generated by alternative pre‐messenger RNA (pre-mRNA) splicing, with canonical roles in controlling the…”
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AUF1 promotes let-7b loading on Argonaute 2
Published in Genes & development (01-08-2015)“…Eukaryotic gene expression is tightly regulated post-transcriptionally by RNA-binding proteins (RBPs) and microRNAs. The RBP AU-rich-binding factor 1 (AUF1)…”
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Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions
Published in The Journal of biological chemistry (25-08-2017)“…Hsp70 is a protein chaperone that prevents protein aggregation and aids protein folding by binding to hydrophobic peptide domains through a reversible…”
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