Search Results - "White, D. Jean"

Macrophage migration inhibitory factor is a cardiac-derived myocardial depressant factor by Garner, Leslie B, Willis, Monte S, Carlson, Deborah L, DiMaio, J Michael, White, Michael D, White, D Jean, Adams, 4th, Glenn A, Horton, Jureta W, Giroir, Brett P

“…Macrophage migration inhibitory factor (MIF) is a pluripotent proinflammatory cytokine that is ubiquitously expressed in organs, including the heart. However,…”
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IRAK1 deletion disrupts cardiac Toll/IL-1 signaling and protects against contractile dysfunction by Thomas, James A, Haudek, Sandra B, Koroglu, Tolga, Tsen, May F, Bryant, Debora D, White, D Jean, Kusewitt, Donna F, Horton, Jureta W, Giroir, Brett P

“…Myocardial contractile dysfunction accompanies both systemic and cardiac insults. Septic shock and burn trauma can lead to reversible contractile deficits,…”
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IRAK contributes to burn-triggered myocardial contractile dysfunction by Thomas, James A, Tsen, May F, White, D Jean, Horton, Jureta W

“…Major burn injury causes myocardial contractile dysfunction, but the molecular basis of this physiological response is incompletely understood. Previous…”
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Tumor necrosis factor-α-induced caspase activation mediates endotoxin-related cardiac dysfunction by Carlson, Deborah L, Willis, Monte S, White, D Jean, Horton, Jureta W, Giroir, Brett P

“…OBJECTIVE:Sepsis-induced cardiac dysfunction is a serious clinical syndrome characterized by hypotension, decreased systemic vascular resistance, and elevated…”
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Increasing percent burn is correlated with increasing inflammation in an adult rodent model by Barber, Robert C, Maass, David L, White, D Jean, Horton, Jureta W

“…Burn injury has been associated with systemic/compartmental inflammatory responses and myocardial dysfunction. We hypothesized that burn size correlates with…”
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Antioxidant vitamin therapy alters sepsis-related apoptotic myocardial activity and inflammatory responses by Carlson, Deborah, Maass, David L, White, D Jean, Tan, Jing, Horton, Jureta W

“…This study examined the effects of antioxidant vitamins on several aspects of sepsis-related myocardial signaling cascades. Sprague-Dawley rats were divided…”
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Effects of burn injury on myocardial signaling and cytokine secretion: Possible role of PKC by Tan, Jing, Maass, David L, White, D Jean, Horton, Jureta W

“…This study examined the effects of major burn injury on the cellular distribution of several PKC isoforms in adult rat hearts and examined the hypothesis that…”
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Burn injury decreases myocardial Na-K-ATPase activity: role of PKC inhibition by Horton, Jureta W, Tan, Jing, White, D Jean, Maass, David L

“…Cardiomyocyte sodium accumulation after burn injury precedes the development of myocardial contractile dysfunction. The present study examined the effects of…”
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Molecular or pharmacologic inhibition of the CD14 signaling pathway protects against burn-related myocardial inflammation and dysfunction by Barber, Robert C, Maass, David L, White, D Jean, Chang, Ling-Yu E, Horton, Jureta W

“…Signaling through toll-like receptor 4 (TLR4) plays an obligate role in burn-related myocardial dysfunction. We hypothesized that signaling through CD14, a…”
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Gender-related differences in myocardial inflammatory and contractile responses to major burn trauma by Horton, Jureta W, White, D Jean, Maass, David L

“…Gender-related differences in immune responses to hemorrhage and sepsis have been described. However, most trauma studies continue to limit experimental models…”
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Bactericidal/permeability increasing protein attenuates the myocardial inflammation/dysfunction that occurs with burn complicated by subsequent infection by Horton, Jureta W, Maass, David L, White, D. Jean, Minei, Joseph P

“…Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas Submitted 31 May 2006 ; accepted in final form 18 June 2007 Intubation…”
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Macrophage migration inhibitory factor mediates late cardiac dysfunction after burn injury by Willis, Monte S, Carlson, Deborah L, Dimaio, J Michael, White, Michael D, White, D Jean, Adams, 4th, Glenn A, Horton, Jureta W, Giroir, Brett P

“…We have recently demonstrated that macrophage migration inhibitory factor (MIF) is a myocardial depressant protein and that MIF mediates late, prolonged…”
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Effects of burn serum on myocardial inflammation and function by HORTON, Jureta W, MAASS, David L, WHITE, D. Jean, SANDERS, Billy, MURPHY, Joseph

“…Large cutaneous burns are clearly recognized to produce acute myocardial contractile dysfunction. This study used a model of burn serum challenge in either…”
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Hypertonic saline dextran after burn injury decreases inflammatory cytokine responses to subsequent pneumonia-related sepsis by Horton, Jureta W, Maass, David L, White, D Jean

“…The present study examined the hypothesis that hypertonic saline dextran (HSD), given after an initial insult, attenuates exaggerated inflammation that occurs…”
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Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock by Binck, Brian W, Tsen, May F, Islas, Miguel, White, D Jean, Schultz, Roger A, Willis, Monte S, Garcia, J Victor, Horton, Jureta W, Thomas, James A

“…How infection precipitates depressed contractility is incompletely understood but may involve the immune, nervous, and endocrine systems as well as the heart…”
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Protective role of heat stress in burn trauma by White, D Jean, Carlson, Deborah, Ordway, George A, Horton, Jureta W

“…OBJECTIVE:This study was designed to determine whether cutaneous burn injury up-regulated expression of myocardial heat shock protein (HSP)70 and to determine…”
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Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma by White, D Jean, Maass, David L, Sanders, Billy, Horton, Jureta W

“…OBJECTIVETo examine the effects of pharmacologic agents designed to limit burn-mediated calcium overload on cardiomyocyte [Ca] and cardiac contractile…”
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I kappa B overexpression in cardiomyocytes prevents NF-kappa B translocation and provides cardioprotection in trauma by Carlson, Deborah L, White, D Jean, Maass, David L, Nguyen, Robin C, Giroir, Brett, Horton, Jureta W

“…This study examined the effects of either IkappaBalpha overexpression (transgenic mice) or N-acetyl-leucinyl-leucinyl-norleucinal (ALLN) administration…”
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Selective decontamination of the digestive tract attenuated the myocardial inflammation and dysfunction that occur with burn injury by Horton, Jureta W, Tan, Jing, White, D Jean, Maass, David L, Thomas, James A

“…This study examined the effects of oral antibiotics to selectively decontaminate the digestive tract (SDD) on postburn myocardial signaling, inflammation, and…”
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Increased cardiomyocyte intracellular calcium during endotoxin-induced cardiac dysfunction in guinea pigs by THOMPSON, M, KLIEWER, A, MAASS, D, BECKER, L, WHITE, D. J, BRYANT, D, ARTEAGA, G, HORTON, J, GIROIR, B. P

“…Septic shock is a complex pathophysiologic state characterized by circulatory insufficiency, multiple system organ dysfunction, and frequent mortality…”
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