Search Results - "White, Charles I."
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A Role for Small RNAs in DNA Double-Strand Break Repair
Published in Cell (30-03-2012)“…Eukaryotes have evolved complex mechanisms to repair DNA double-strand breaks (DSBs) through coordinated actions of protein sensors, transducers, and…”
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2
DMC1 attenuates RAD51-mediated recombination in Arabidopsis
Published in PLoS genetics (25-08-2022)“…Ensuring balanced distribution of chromosomes in gametes, meiotic recombination is essential for fertility in most sexually reproducing organisms. The repair…”
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3
Meiotic double-strand break repair DNA synthesis tracts in Arabidopsis thaliana
Published in PLoS genetics (16-07-2024)“…We report here the successful labelling of meiotic prophase I DNA synthesis in the flowering plant, Arabidopsis thaliana. Incorporation of the thymidine…”
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4
Centromere Associations in Meiotic Chromosome Pairing
Published in Annual review of genetics (23-11-2015)“…Production of gametes of halved ploidy for sexual reproduction requires a specialized cell division called meiosis. The fusion of two gametes restores the…”
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5
RAD54 forms DNA repair foci in response to DNA damage in living plant cells
Published in The Plant journal : for cell and molecular biology (01-04-2017)“…Summary Plants have various defense mechanisms against environmental stresses that induce DNA damage. Genetic and biochemical analyses have revealed the…”
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6
Meiotic recombination in Arabidopsis is catalysed by DMC1, with RAD51 playing a supporting role
Published in PLoS genetics (01-09-2013)“…Recombination establishes the chiasmata that physically link pairs of homologous chromosomes in meiosis, ensuring their balanced segregation at the first…”
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7
RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis
Published in PLoS genetics (18-05-2021)“…An essential component of the homologous recombination machinery in eukaryotes, the RAD54 protein is a member of the SWI2/SNF2 family of helicases with…”
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8
The Role of Topoisomerase II in DNA Repair and Recombination in Arabidopsis thaliana
Published in International journal of molecular sciences (04-12-2021)“…DNA entanglements and supercoiling arise frequently during normal DNA metabolism. DNA topoisomerases are highly conserved enzymes that resolve the topological…”
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9
Roles of XRCC2, RAD51B and RAD51D in RAD51-independent SSA recombination
Published in PLoS genetics (01-11-2013)“…The repair of DNA double-strand breaks by recombination is key to the maintenance of genome integrity in all living organisms. Recombination can however…”
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10
Kinetic analysis of DNA double-strand break repair pathways in Arabidopsis
Published in DNA repair (10-06-2011)“…► Complex interrelationships of recombination pathways poorly understood. ► Quantitation of g-H2AX foci permits DSB repair kinetics analysis in Arabidopsis. ►…”
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11
Analysis of the impact of the absence of RAD51 strand exchange activity in Arabidopsis meiosis
Published in PloS one (10-08-2017)“…The ploidy of eukaryote gametes must be halved to avoid doubling of numbers of chromosomes with each generation and this is carried out by meiosis, a…”
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12
Distinct Roles of the ATR Kinase and the Mre11-Rad50-Nbs1 Complex in the Maintenance of Chromosomal Stability in Arabidopsis
Published in The Plant cell (01-09-2010)“…Signaling of chromosomal DNA breaks is of primary importance for initiation of repair and, thus, for global genomic stability. Although the Mre11-Rad50-Nbs1…”
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13
Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana
Published in PLoS genetics (01-04-2012)“…During meiosis homologous chromosomes pair, recombine, and synapse, thus ensuring accurate chromosome segregation and the halving of ploidy necessary for…”
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14
Multiple host‐cell recombination pathways act in Agrobacterium‐mediated transformation of plant cells
Published in The Plant journal : for cell and molecular biology (01-02-2014)“…Using floral‐dip, tumorigenesis and root callus transformation assays of both germline and somatic cells, we present here results implicating the four major…”
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15
Effects of XRCC2 and RAD51B mutations on somatic and meiotic recombination in Arabidopsis thaliana
Published in The Plant journal : for cell and molecular biology (01-06-2013)“…Summary Homologous recombination is key to the maintenance of genome integrity and the creation of genetic diversity. At the mechanistic level, recombination…”
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16
Context effects on repair of 5′‐overhang DNA double‐strand breaks induced by Cas12a in Arabidopsis
Published in Plant direct (01-10-2024)“…Sequence‐specific endonucleases have been key to the study of the mechanisms and control of DNA double‐strand break (DSB) repair and recombination, and the…”
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17
Responses to telomere erosion in plants
Published in PloS one (21-01-2014)“…In striking contrast to animals, plants are able to develop and reproduce in the presence of significant levels of genome damage. This is seen clearly in both…”
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Arabidopsis thaliana RNase H2 Deficiency Counteracts the Needs for the WEE1 Checkpoint Kinase but Triggers Genome Instability
Published in The Plant cell (01-09-2014)“…The WEE1 kinase is an essential cell cycle checkpoint regulator in Arabidopsis thaliana plants experiencing replication defects. Whereas under non-stress…”
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Recombination-Independent Mechanisms and Pairing of Homologous Chromosomes during Meiosis in Plants
Published in Molecular plant (01-03-2014)“…Meiosis is the specialized eukaryotic cell division that permits the halving of ploidy necessary for game- togenesis in sexually reproducing organisms, This…”
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Journal Article Book Review -
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Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair
Published in The Plant journal : for cell and molecular biology (01-02-2005)“…In addition to the recombinase Rad51, vertebrates have five paralogs of Rad51, all members of the Rad51-dependent recombination pathway. These paralogs form…”
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