Search Results - "White, Catherine A."

Gas chromatography/negative chemical ionization mass spectrometry of transfluthrin in rat plasma and brain by Hooshfar, Shirin, Mortuza, Tanzir B., Rogers, Clinton A., Linzey, Michael R., Gullick, Darren R., Bruckner, James V., White, Catherine A., Bartlett, Michael G.

“…Rationale Transfluthrin is a relatively non‐toxic rapid‐acting synthetic pyrethroid insecticide. It is widely used in household and hygiene products. A…”
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Pseudopterosin A: Protection of Synaptic Function and Potential as a Neuromodulatory Agent by Caplan, Stacee Lee, Zheng, Bo, Dawson-Scully, Ken, White, Catherine A, West, Lyndon M

“…Natural products have provided an invaluable source of inspiration in the drug discovery pipeline. The oceans are a vast source of biological and chemical…”
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Effect of Propranolol on Functional Connectivity in Autism Spectrum Disorder—A Pilot Study by Narayanan, Ananth, White, Catherine A, Saklayen, Sanjida, Scaduto, Mary J, Carpenter, Allen L, Abduljalil, Amir, Schmalbrock, Petra, Beversdorf, David Q

“…A decrease in interaction between brain regions is observed in individuals with autism spectrum disorder (ASD), which is believed to be related to restricted…”
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Simultaneous determination of abacavir and zidovudine from rat tissues using HPLC with ultraviolet detection by Lewis, Summer R., White, Catherine A., Bartlett, Michael G.

“…A simple high-performance liquid chromatography (HPLC) method has been developed and validated for the simultaneous determination of abacavir and zidovudine…”
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Ontogeny of plasma proteins, albumin and binding of diazepam, cyclosporine, and deltamethrin by Sethi, Pankaj K., White, Catherine A., Cummings, Brian S., Hines, Ronald N., Muralidhara, Srinivasa, Bruckner, James V.

“…Background: To characterize the ontogeny of plasma albumin and total proteins, due to the lack of a comprehensive pediatric database. Secondly, to establish…”
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Toxicokinetics of Deltamethrin: Dosage Dependency, Vehicle Effects, and Low-Dose Age-Equivalent Dosimetry in Rats by Mortuza, Tanzir, Chen, Chen, White, Catherine A, Cummings, Brian S, Muralidhara, Srinivasa, Gullick, Darren, Bruckner, James V

“…Abstract There is increasing concern that infants and children may be at increased risk of neurological effects of pyrethroids, the most widely used class of…”
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Prodrug Strategies for the Development of β‑l‑5-((E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l‑BHDU) against Varicella Zoster Virus (VZV) by Singh, Uma S., Konreddy, Ananda K., Kothapalli, Yugandhar, Liu, Dongmei, Lloyd, Megan G., Annavarapu, Vidya, White, Catherine A., Bartlett, Michael. G., Moffat, Jennifer F., Chu, Chung K.

“…Varicella zoster virus (VZV) establishes lifelong infection after primary disease and can reactivate. Several drugs are approved to treat VZV diseases, but new…”
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Toxicokinetics of cis- and trans-Permethrin: Influence of Isomer, Maturation, and Sex by Pang, Jing, Mortuza, Tanzir, White, Catherine A, Muralidhara, Srinavasa, Cummings, Brian S, Bruckner, James V

“…Abstract Permethrin exposure of children and adults is widespread in many populations, but knowledge of its relative toxicokinetics (TK) and health risks in…”
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Determination of deltamethrin and its metabolite 3-phenoxybenzoic acid in male rat plasma by high-performance liquid chromatography by YAN DING, WHITE, Catherine A, MURALIDHARA, S, BRUCKNER, James V, BARTLETT, Michael G

“…The pyrethroid insecticide-deltamethrin [(S)-alpha-cyano-3-phenoxybenzyl-(1R)-cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylate] is widely used…”
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Age-Dependency of Blood-Brain Barrier Penetration by cis- and trans-Permethrin in the Rat by Mortuza, Tanzir, Edwards, Gaylen L, White, Catherine A, Patel, Vandan, Cummings, Brian S, Bruckner, James V

“…Permethrin (PER), a Type I pyrethroid, is the most widely used insecticide in domestic settings in the U.S. The overall objective of this study was to assess…”
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Plasma Protein and Lipoprotein Binding of Cis - and Trans -Permethrin and Deltamethrin in Adult Humans and Rats by Sethi, Pankaj, Bruckner, James V, Mortuza, Tanzir B, Cummings, Brian S, Muralidhara, Srinivasa, White, Catherine A

“…The majority of residents of the United States, Canada, and Europe are exposed to pyrethroids, the most commonly used class of insecticides. Surprisingly…”
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Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin by Amaraneni, Manoj, Sharma, Anshika, Pang, Jing, Muralidhara, Srinivasa, Cummings, Brian S., White, Catherine A., Bruckner, James V., Zastre, Jason

“…•Deltamethrin (DLM) is not a P-glycoprotein substrate or inhibitor.•The extent of DLM permeation into the brain is dependent on protein binding.•Transport of…”
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Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation by Song, Gina, Moreau, Marjory, Efremenko, Alina, Lake, Brian G, Wu, Huali, Bruckner, James V, White, Catherine A, Osimitz, Thomas G, Creek, Moire R, Hinderliter, Paul M, Clewell, Harvey J, Yoon, Miyoung

“…Abstract An in vitro to in vivo (IVIVE) extrapolation based-physiologically based pharmacokinetic (PBPK) modeling approach was demonstrated to understand…”
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Effect of dose and exposure protocol on the toxicokinetics and first-pass elimination of trichloroethylene and 1,1,1-trichloroethane by Mortuza, Tanzir, Muralidhara, Srinivasa, White, Catherine A., Cummings, Brian S., Hines, Carey, Bruckner, James V.

“…Trichloroethylene (TCE) and 1,1,1-trichloroethane (TRI) are frequent contaminants of drinking water and of groundwater at hazardous waste sites. There is…”
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Determination of lamivudine in plasma, amniotic fluid, and rat tissues by liquid chromatography by Alnouti, Yazen, White, Catherine A., Bartlett, Michael G.

“…An HPLC method for the quantification of lamivudine (3TC) in rat plasma, amniotic fluid, placental and fetal tissues has been developed, validated and applied…”
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Brain uptake of deltamethrin in rats as a function of plasma protein binding and blood–brain barrier maturation by Amaraneni, Manoj, Pang, Jing, Mortuza, Tanzir B., Muralidhara, Srinivasa, Cummings, Brian S., White, Catherine A., Vorhees, Charles V., Zastre, Jason, Bruckner, James V.

“…•High brain levels of pyrethroids result in increased neurotoxicity in immature rats.•Low metabolic inactivation of parent pyrethroids results in elevated…”
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Influence of Maturation on In Vivo Tissue to Plasma Partition Coefficients for Cis- and Trans-Permethrin by Amaraneni, Manoj, Pang, Jing, Bruckner, James V, Muralidhara, Srinivasa, Mortuza, Tanzir B, Gullick, Darren, Hooshfar, Shirin, White, Catherine A, Cummings, Brian S

“…Permethrin, the most widely used household insecticide in the United States, is marketed as a mixture of its cis (CIS) and trans (TRANS) isomers. The major…”
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Pharmacokinetics of Intravenous Acyclovir, Zidovudine, and Acyclovir-Zidovudine in Pregnant Rats by BROWN, Stacy D, BARTLETT, Michael G, WHITE, Catherine A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Measurement of plasma protein and lipoprotein binding of pyrethroids by Sethi, Pankaj K., Muralidhara, S., Bruckner, James V., White, Catherine A.

“…A simple, reliable procedure was developed to measure binding of pyrethroid insecticides to total proteins and lipoproteins of rat and human plasma. The extent…”
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Age, dose, and time-dependency of plasma and tissue distribution of deltamethrin in immature rats by Kim, Kyu-Bong, Anand, Sathanandam S, Kim, Hyo J, White, Catherine A, Fisher, Jeffrey W, Tornero-Velez, Rogelio, Bruckner, James V

“…The major objective of this project was to characterize the systemic disposition of the pyrethroid, deltamethrin (DLT), in immature rats, with emphasis on the…”
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