Search Results - "White, Andre"
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Context and Auditory Fear are Differentially Regulated by HDAC3 Activity in the Lateral and Basal Subnuclei of the Amygdala
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2017)“…Histone acetylation is a fundamental epigenetic mechanism that is dynamically regulated during memory formation. Histone acetyltransferases (HATs) and histone…”
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Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice
Published in Nature medicine (01-08-2020)“…Cancer cachexia is a highly prevalent condition associated with poor quality of life and reduced survival 1 . Tumor-induced perturbations in the endocrine,…”
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3
Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
Published in Nature (London) (12-10-2017)“…GDNF receptor alpha-like is a brainstem-restricted receptor for growth and differentiation factor 15, regulating appetite and body weight in non-homeostatic…”
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Pectic oligosaccharide structure-function relationships: Prebiotics, inhibitors of Escherichia coli O157:H7 adhesion and reduction of Shiga toxin cytotoxicity in HT29 cells
Published in Food chemistry (15-07-2017)“…•Determined bifidogenic citrus pectic oligosaccharide (POS) structural diversity.•Five citrus POS were anti-adhesive for Stx-producing E. coli…”
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5
Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1
Published in Nature communications (22-02-2021)“…Programmed death-ligand 1 is a glycoprotein expressed on antigen presenting cells, hepatocytes, and tumors which upon interaction with programmed death-1,…”
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6
Antimicrobial activity of thermophilin 110 against the opportunistic pathogen Cutibacterium acnes
Published in Biotechnology letters (01-10-2023)“…Objective Thermophilin 110, a bacteriocin produced by Streptococcus thermophilus B59671, inhibited planktonic growth and biofilm formation of Cutibacterium…”
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Flexible Behavioral Adjustment to Frustrative Nonreward in Anticipatory Behavior, but Not in Consummatory Behavior, Requires the Dorsal Hippocampus
Published in Hippocampus (01-12-2024)“…ABSTRACT The hippocampus (HC) is recognized for its pivotal role in memory‐related plasticity and facilitating adaptive behavioral responses to reward shifts…”
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RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist
Published in PloS one (31-12-2013)“…Increased synthesis of Apolipoprotein A-I (ApoA-I) and HDL is believed to provide a new approach to treating atherosclerosis through the stimulation of reverse…”
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RVX-297- a novel BD2 selective inhibitor of BET bromodomains
Published in Biochemical and biophysical research communications (12-08-2016)“…Bromodomains are epigenetic readers that specifically bind to the acetyl lysine residues of histones and transcription factors. Small molecule BET bromodomain…”
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10
Identification of Lactobacillus Strains Capable of Fermenting Fructo-Oligosaccharides and Inulin
Published in Microorganisms (Basel) (24-09-2021)“…Novel probiotic strains that can ferment prebiotics are important for functional foods. The utilization of prebiotics is strain specific, so we screened 86…”
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11
General and Special Catalyst for Suzuki-Miyaura Coupling Processes
Published in Angewandte Chemie (International ed.) (09-08-2010)“…Biaryl monophosphorus ligands containing a 2,3‐dihydrobenzo[d][1,3]oxaphosphole framework are highly effective for the palladium‐catalyzed Suzuki–Miyaura…”
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12
Epigenetic regulation of immediate-early gene Nr4a2/Nurr1 in the medial habenula during reinstatement of cocaine-associated behavior
Published in Neuropharmacology (15-07-2019)“…Propensity to relapse following long periods of abstinence is a key feature of substance use disorder. Drugs of abuse, such as cocaine, cause long-term changes…”
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13
Cranberry Arabino-Xyloglucan and Pectic Oligosaccharides Induce Lactobacillus Growth and Short-Chain Fatty Acid Production
Published in Microorganisms (Basel) (03-07-2022)“…Numerous health benefits have been reported from the consumption of cranberry-derived products, and recent studies have identified bioactive polysaccharides…”
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14
Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase
Published in The Journal of biological chemistry (18-02-2005)“…Pim-1 kinase is a member of a distinct class of serine/threonine kinases consisting of Pim-1, Pim-2, and Pim-3. Pim kinases are highly homologous to one…”
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15
Structural characterization of strawberry pomace
Published in Heliyon (15-05-2024)“…Strawberries are a nutrient dense food rich in vitamins, minerals, non-nutrient antioxidant phenolics, and fibers. Strawberry fiber bioactive structures are…”
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16
Novel and Efficient Chiral Bisphosphorus Ligands for Rhodium-Catalyzed Asymmetric Hydrogenation
Published in Organic letters (05-03-2010)“…A series of structurally novel, operationally convenient, and efficient chiral 2-phosphino-2,3-dihydrobenzo[d][1,3]oxaphosphole ligands was developed…”
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17
Molecular basis of MAPK-activated protein kinase 2:p38 assembly
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2007)“…p38 MAPK and MAPK-activated protein kinase 2 (MK2) are key components of signaling pathways leading to many cellular responses, notably the proinflammatory…”
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Promoter-Specific Effects of DREADD Modulation on Hippocampal Synaptic Plasticity and Memory Formation
Published in The Journal of neuroscience (23-03-2016)“…Designer receptors exclusively activated by designer drug (DREADDs) are a novel tool with the potential to bidirectionally drive cellular, circuit, and…”
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Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory
Published in Nature communications (20-08-2018)“…Aging is accompanied by impairments in both circadian rhythmicity and long-term memory. Although it is clear that memory performance is affected by circadian…”
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Effects of uniquely processed cowpea and plantain flours on wheat bread properties
Published in Journal of food processing and preservation (01-08-2015)“…The effect of incorporating uniquely processed whole-seed cowpeas or plantain flours at 10 or 20 g/100 g in all-purpose flour on paste viscosity and…”
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