Search Results - "White, Amy C"

Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects by Medeiros, Lea A, Dennis, Lucas M, Gill, Mark E, Houbaviy, Hristo, Markoulaki, Styliani, Fu, Dongdong, White, Amy C, Kirak, Oktay, Sharp, Phillip A, Page, David C, Jaenisch, Rudolf

“…Mir-290 through mir-295 (mir-290–295) is a mammalian-specific microRNA (miRNA) cluster that, in mice, is expressed specifically in early embryos and embryonic…”
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Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo by Foster, Donald J, Barros, Scott, Duncan, Rick, Shaikh, Sarfraz, Cantley, William, Dell, Amy, Bulgakova, Elena, O'Shea, Jonathan, Taneja, Nate, Kuchimanchi, Satya, Sherrill, Christopher B, Akinc, Akin, Hinkle, Gregory, Seila White, Amy C, Pang, Bo, Charisse, Klaus, Meyers, Rachel, Manoharan, Muthiah, Elbashir, Sayda M

“…Since the discovery of RNA interference (RNAi), researchers have identified a variety of small interfering RNA (siRNA) structures that demonstrate the ability…”
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First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement by Tabernero, Josep, Shapiro, Geoffrey I, LoRusso, Patricia M, Cervantes, Andres, Schwartz, Gary K, Weiss, Glen J, Paz-Ares, Luis, Cho, Daniel C, Infante, Jeffrey R, Alsina, Maria, Gounder, Mrinal M, Falzone, Rick, Harrop, Jamie, White, Amy C Seila, Toudjarska, Iva, Bumcrot, David, Meyers, Rachel E, Hinkle, Gregory, Svrzikapa, Nenad, Hutabarat, Renta M, Clausen, Valerie A, Cehelsky, Jeffrey, Nochur, Saraswathy V, Gamba-Vitalo, Christina, Vaishnaw, Akshay K, Sah, Dinah W Y, Gollob, Jared A, Burris, 3rd, Howard A

“…RNA interference (RNAi) is a potent and specific mechanism for regulating gene expression. Harnessing RNAi to silence genes involved in disease holds promise…”
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3′-Modification stabilizes mRNA and increases translation in cells by Gampe, Christian, White, Amy C. Seila, Siva, Swetha, Zécri, Frédéric, Diener, John

“…[Display omitted] •3′-Modified RNAs were synthesized in synthetically useful yields.•These RNAs showed increased stability toward exonuclease…”
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