Search Results - "Whitcomb, Mark"

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  1. 1
    Total Synthesis of Caerulomycin C via the Halogen Dance Reaction

    Total Synthesis of Caerulomycin C via the Halogen Dance Reaction by Sammakia, Tarek, Stangeland, Eric L, Whitcomb, Mark C

    Published in Organic letters (11-07-2002)
    “…The total synthesis of caerulomycin C is described. Key steps in this synthesis utilize 1,2-, 1,3-, and 1,4-halogen dance reactions for the functionalization…”
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  2. 2
    Synthesis, Resolution, and Determination of Absolute Configuration of a Vaulted 2,2‘-Binaphthol and a Vaulted 3,3‘-Biphenanthrol (VAPOL)

    Synthesis, Resolution, and Determination of Absolute Configuration of a Vaulted 2,2‘-Binaphthol and a Vaulted 3,3‘-Biphenanthrol (VAPOL) by Bao, Jianming, Wulff, William D, Dominy, James B, Fumo, Michael J, Grant, Eugene B, Rob, Alexander C, Whitcomb, Mark C, Yeung, Siu-Man, Ostrander, Robert L, Rheingold, Arnold L

    Published in Journal of the American Chemical Society (10-04-1996)
    “…Two methods for the synthesis of vaulted biaryls were developed involving the reactions of carbene complexes with alkynes and the [2 + 2] cycloaddition of…”
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  3. 3
    Reaction of Fischer Carbene Complexes with 1,3-Butadiynes:  A New Strategem for Biaryl Synthesis with Construction of the Biaryl Bond Preceding Synthesis of the Arenes

    Reaction of Fischer Carbene Complexes with 1,3-Butadiynes:  A New Strategem for Biaryl Synthesis with Construction of the Biaryl Bond Preceding Synthesis of the Arenes by Bao, Jianming, Wulff, William D, Fumo, Michael J, Grant, Eugene B, Heller, Douglas P, Whitcomb, Mark C, Yeung, Siu-Man

    Published in Journal of the American Chemical Society (06-03-1996)
    “…The first examples of the reactions of Fischer carbene complexes with 1,3-butadiynes are reported. These reactions are of interest since they provide new…”
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  4. 4
    Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

    Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties by Kirschberg, Thorsten A., Metobo, Sammy, Clarke, Michael O., Aktoudianakis, Vangelis, Babusis, Darius, Barauskas, Ona, Birkus, Gabriel, Butler, Thomas, Byun, Daniel, Chin, Gregory, Doerffler, Edward, Edwards, Thomas E., Fenaux, Martijn, Lee, Rick, Lew, Willard, Mish, Michael R., Murakami, Eisuke, Park, Yeojin, Squires, Neil H., Tirunagari, Neeraj, Wang, Ting, Whitcomb, Mark, Xu, Jie, Yang, Huiling, Ye, Hong, Zhang, Lijun, Appleby, Todd C., Feng, Joy Y., Ray, Adrian S., Cho, Aesop, Kim, Choung U.

    Published in Bioorganic & medicinal chemistry letters (15-04-2017)
    “…[Display omitted] A series of 2′-fluorinated C-nucleosides were prepared and tested for anti-HCV activity. Among them, the triphosphate of…”
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  5. 5
    The tin dance reaction, synthesis of heterocycles, and studies on a model system for the synthesis of diazonamide A

    The tin dance reaction, synthesis of heterocycles, and studies on a model system for the synthesis of diazonamide A by Whitcomb, Mark Charles

    Published 01-01-2003
    “…This dissertation details synthetic efforts toward two highly substituted polyaromatic natural products, caerulomycin C and diazonamide A; and the development…”
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