Search Results - "Whiss, Per A."
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Growth Differentiation Factor 15 and Matrix Metalloproteinase 3 in Plasma as Biomarkers for Neuropathy and Nephropathy in Type 1 Diabetes
Published in International journal of molecular sciences (03-07-2024)“…Diabetic neuropathy and nephropathy are common complications of type 1 diabetes (T1D). The symptoms are often elusive in the early stages, and available…”
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Platelet adhesion in type 2 diabetes: impact of plasma albumin and mean platelet volume
Published in Thrombosis journal (02-06-2021)“…Background Altered mean platelet volume (MPV) and plasma albumin has been reported in type 2 diabetes (T2D). MPV is suggested to predict cardiovascular risk…”
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3
Systemic biomarkers of microvascular alterations in type 1 diabetes associated neuropathy and nephropathy - A prospective long-term follow-up study
Published in Journal of diabetes and its complications (01-12-2023)“…This study aimed to investigate circulating biomarkers associated with the risk of developing diabetic peripheral neuropathy (DPN) and nephropathy in type 1…”
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4
IN VITRO EFFECTS OF ANTIPSYCHOTICS ON HUMAN PLATELET ADHESION AND AGGREGATION AND PLASMA COAGULATION
Published in Clinical and experimental pharmacology & physiology (01-08-2007)“…SUMMARY 1 Several studies suggest an association between venous thromboembolism and the use of antipsychotic drugs, especially clozapine, but the biological…”
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Measurement of adhesion of human platelets in plasma to protein surfaces in microplates
Published in Journal of pharmacological and toxicological methods (01-11-2005)“…Platelet adhesion is an initial, crucial and complex event for inhibiting blood loss upon vascular injury. Activation and adhesion of platelets also play a…”
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6
Weak relationship between ionized and total magnesium in serum of patients requiring magnesium status
Published in Biological trace element research (01-01-2007)“…Measurement and monitoring of magnesium (Mg) are important to prevent the development of serious and potentially fatal complications in critically ill…”
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7
Higher platelet P-selectin in male patients with inflammatory bowel disease compared to healthy males
Published in World journal of gastroenterology : WJG (28-02-2006)“…AIM: To observe if the total amount of platelet P-selectin (tP-selectin) in patients with inflammatory bowel disease (IBD) was related to disease entity or…”
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Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study
Published in Journal of translational medicine (09-06-2009)“…Despite the use of anti-platelet agents such as acetylsalicylic acid (ASA) and clopidogrel in coronary heart disease, some patients continue to suffer from…”
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Plasma levels of tissue inhibitor of metalloproteinase-1 in patients with type 1 diabetes mellitus associate with early diabetic neuropathy and nephropathy
Published in Diabetes & vascular disease research (01-03-2021)“…Background: Tissue inhibitor of metalloproteinase-1 (TIMP-1) has been suggested as a marker for abnormal regulation of tissue remodelling in type 1 diabetes…”
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10
Enhanced platelet adhesion in essential thrombocythemia after in vitro activation
Published in Turkish journal of haematology (01-06-2010)“…Essential thrombocythemia (ET) is a chronic myeloproliferative disorder characterized by elevated platelet counts and increased risk of thrombosis. Ex vivo…”
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In vitro effects of serotonin and noradrenaline reuptake inhibitors on human platelet adhesion and coagulation
Published in Pharmacological reports (2012)“…Although several studies show that there is an increased risk of bleeding events during antidepressant treatment with selective serotonin reuptake inhibitors…”
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12
Nanomolar concentrations of adrenaline induce platelet adhesion in vitro
Published in Platelets (Edinburgh) (01-01-2013)“…Adrenaline is a platelet activator having a resting plasma concentration of <1 nmol/l that increases to a few nmol/l during stress. However, most in vitro…”
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Effects of nicotine, its metabolites and tobacco extracts on human platelet function in vitro
Published in Toxicology in vitro (01-03-2013)“…► Tobacco extracts inhibit platelet adhesion to proteins surfaces. ► This effect is independent of nitric oxide and a platelet nicotine receptor. ► Nicotine…”
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Characterization of static adhesion of human platelets in plasma to protein surfaces in microplates
Published in Blood coagulation & fibrinolysis (01-04-2009)“…Platelet adhesion is a complex and important event for prevention of blood loss after vessel injury. This study investigated fundamental adhesive mechanisms…”
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Adhesion of human platelets to albumin is synergistically increased by lysophosphatidic acid and adrenaline in a donor-dependent fashion
Published in Blood coagulation & fibrinolysis (01-07-2006)“…Lysophosphatidic acid (LPA) and adrenaline are weak platelet activators considered important for thrombus formation, and were previously shown to…”
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Cross-talk between adenosine and the oxatriazole derivative GEA 3175 in platelets
Published in European journal of pharmacology (11-07-2005)“…We examined the interplay between adenosine and the nitric oxide (NO)-containing oxatriazole derivative GEA 3175 in human platelets. The importance of cyclic…”
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Pexelizumab Alexion
Published in Current opinion in investigational drugs (London, England : 2000) (01-06-2002)“…Alexion and Procter & Gamble (P&G) are developing pexelizumab (h5G1.1-SC), a short-acting, recombinant complement C5 inhibitor for the potential treatment of…”
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Nitric oxide donors and angiotensin-converting enzyme inhibitors act in concert to inhibit human angiotensin-converting enzyme activity and platelet aggregation in vitro
Published in European journal of pharmacology (06-10-2000)“…This study investigates the effects of exogenous and endogenous nitric oxide (NO) on human circulating and endothelial angiotensin-converting enzyme activity…”
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Divalent cations and the protein surface co-ordinate the intensity of human platelet adhesion and P-selectin surface expression
Published in Blood coagulation & fibrinolysis (01-07-2002)“…At sites of blood vessel injury, platelets adhere to exposed vessel components, such as collagen, or immobilized fibrinogen derived from plasma or activated…”
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Comparison of Plasma Levels of Cytokines and In Vitro Generation of Reactive Oxygen Species After Nicotine Infusion in Nicotine Users with Normal and Impaired Renal Function
Published in Immunopharmacology and immunotoxicology (01-01-2003)“…Several in vitro and animal studies suggest effects of nicotine on the immune system, but little evidence exists regarding the in vivo immunomodulation of…”
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