Search Results - "Whigan, D B"

Effect of food on pravastatin pharmacokinetics and pharmacodynamics by Pan, H Y, DeVault, A R, Brescia, D, Willard, D A, McGovern, M E, Whigan, D B, Ivashkiv, E

“…The pharmacokinetics and pharmacodynamics of pravastatin 20 mg administered twice daily when taken with or one hour before meals were evaluated in 24…”
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Ternary-column system for high-throughput direct-injection bioanalysis by liquid chromatography/tandem mass spectrometry by Xia, Yuan-Qing, Whigan, Daisy B., Powell, Mark L., Jemal, Mohammed

“…As a continuation of our efforts to improve our high‐flow on‐line bioanalytical approach for high‐throughput quantitation of drugs and metabolites in…”
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Determination of pravastatin sodium and its isomeric metabolite in human urine by HPLC with UV detection by Whigan, D B, Ivashkiv, E, Cohen, A I

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High-performance liquid chromatographic assay for the quantitation of irbesartan (SR 47436/BMS-186295) in human plasma and urine by Chang, Shu-Ying, Whigan, Daisy B, Vachharajani, Nimish N, Patel, Rajesh

“…A selective, accurate, precise and reproducible high-performance liquid chromatographic assay was developed for the quantitation of irbesartan, an angiotensin…”
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BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs by Grover, G J, Parham, C S, Whigan, D B, Mitroka, J G

“…BMS-180448 has been found to retain the cardioprotective potency of its chemically related analog, cromakalim, although having significantly less peripheral…”
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A simple liquid-liquid extraction with hexane for low-picogram determination of drugs and their metabolites in plasma by high-performance liquid chromatography with positive ion electrospray tandem mass spectrometry by Xia, Yuan-Qing, Whigan, Daisy B., Jemal, Mohammed

“…Four sensitive, specific and accurate methods, based on high‐performance liquid chromatography (HPLC) with positive ion electrospray tandem mass spectrometry…”
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High-performance liquid chromatographic determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite (E)-5-(2-bromovinyl)uracil in serum by Whigan, D B, Cohen, A I

“…A high-performance liquid chromatographic method was developed to assay 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite…”
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The use of high-flow high performance liquid chromatography coupled with positive and negative ion electrospray tandem mass spectrometry for quantitative bioanalysis via direct injection of the plasma/serum samples by Jemal, M., Yuan-Qing, Whigan, Daisy B.

“…Two bioanalytical methods have been developed and validated utilizing high flow high performance liquid chromatography (HPLC) for on‐line purification of…”
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Liquid chromatography/tandem mass spectrometry methods for quantitation of mevalonic acid in human plasma and urine: method validation, demonstration of using a surrogate analyte, and demonstration of unacceptable matrix effect in spite of use of a stable isotope analog internal standard by Jemal, Mohammed, Schuster, Alan, Whigan, Daisy B.

“…Selective, accurate, and reproducible liquid chromatography/tandem mass spectrometry (LC/MS/MS) methods were developed and validated for the determination of…”
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Manual and automated determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and its metabolite (E)-5-(2-bromovinyl)uracil in urine by Whigan, D B, Schuster, A E

“…This paper describes the determination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in urine. The method involves sample clean-up by liquid-liquid…”
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Reaction between phosphorus trichloride and 1,1-dimethylhydrazine by Whigan, Daisy B, Gilje, John W, Goya, Amy E

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