Search Results - "Whicher, J. T."

New international reference preparation for proteins in human serum (RPPHS) by Whicher, J T, Ritchie, R F, Johnson, A M, Baudner, S, Bienvenu, J, Blirup-Jensen, S, Carlstrom, A, Dati, F, Ward, A M, Svendsen, P J

“…Quality-control surveys in recent years, in various parts of the world, have shown poor between-laboratory agreement for measurements of plasma proteins…”
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Cytokines in disease by Whicher, J T, Evans, S W

“…Cytokines are peptides used by immune and inflammatory cells to communicate with each other and to control the milieu interieur in which they operate. Recent…”
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The acute phase protein response in patients receiving subcutaneous IL‐6 by BANKS, R. E., FORBES, M. A., STORR, M., HIGGINSON, J., THOMPSON, D., RAYNES, J., ILLINGWORTH, J. M., PERREN, T. J., SELBY, P. J., WHICHER, J. T.

“…SUMMARY IL‐6, tumour necrosis factor‐α (TNE‐α) and IL‐1 are thought to be the key mediators of the acute phase response although much of the evidence is based…”
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The value of acute phase protein measurements in clinical practice by Thompson, D, Milford-Ward, A, Whicher, J T

“…There is clearly a role for the measurement of acute phase proteins and other indices of the acute phase reaction but it is equally clear that no one…”
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Interleukin‐6 and ACTH act synergistically to stimulate the release of corticosterone from adrenal gland cells by SALAS, M. A., EVANS, S. W., LEVELL, M. J., WHICHER, J. T.

“…SUMMARY We investigated whether interleukin‐6 (IL‐6) could cause the release of corticosterone by a direct interaction with the adrenal gland. Primary cultures…”
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Synovial fluid concentration of five different cytokines in rheumatic diseases by Westacott, C I, Whicher, J T, Barnes, I C, Thompson, D, Swan, A J, Dieppe, P A

“…Interleukin-1 beta, interleukin-2, tumour necrosis factor alpha, and the interferons, alfa and gamma, were measured concurrently in synovial fluid samples from…”
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Factors affecting the measurement of cytokines in biological fluids: implications for their clinical measurement by Heney, D, Whicher, J T

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Effect of certified reference material 470 (CRM 470) on national quality assurance programs for serum proteins in Europe by Johnson, A M, Whicher, J T

“…The introduction of the international reference material for serum proteins, CRM 470, has resulted in significant reduction of the among-laboratory variance…”
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Reduction in circulating levels of CD4-positive lymphocytes in acute pancreatitis: relationship to endotoxin, interleukin 6 and disease severity by Curley, P J, McMahon, M J, Lancaster, F, Banks, R E, Barclay, G R, Shefta, J, Boylston, A W, Whicher, J T

“…The proportion of peripheral blood mononuclear cells expressing the T helper cell phenotype and levels of antiendotoxin core antibody, interleukin (IL) 6 and…”
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Interleukin-6 and Its Relationship to C-Reactive Protein and Fever in Children with Febrile Neutropenia by Heney, D., Lewis, I. J., Evans, S. W., Banks, R., Bailey, C. C., Whicher, J. T.

“…The assessment of febrile neutropenia is problematic. C-reactive protein (CRP) values alone do not differentiate those patients with microbiologically…”
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The existing interim consensus reference ranges and the future approach by Dati, F, Johnson, A M, Whicher, J T

“…The release of the reference material for serum proteins, CRM 470/RPPHS, in 1993, has given rise to a great improvement in the between-laboratory variability…”
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Effects of resuscitation fluids on T cell immune responses by Sillett, H K, Whicher, J T, Trejdosiewicz, L K

“…This study was designed to determine whether dextran, gelatin or hydroxyethyl starch-based colloidal resuscitation fluids (CRF) are inhibitory to T lymphocyte…”
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Effects of resuscitation fluids on nonadaptive immune responses by Sillett, H.K., Whicher, J.T., Trejdosiewicz, L.K.

“…BACKGROUND: Colloidal plasma‐expander fluids are commonly used as an alternative to blood components in the resuscitation of patients suffering from…”
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Expression of interleukin-6 by intestinal enterocytes by Jones, S C, Trejdosiewicz, L K, Banks, R E, Howdle, P D, Axon, A T, Dixon, M F, Whicher, J T

“…AIMS--To investigate the cellular source of the cytokine interleukin-6 (IL-6) in the small and large intestines of patients with inflammatory bowel disease,…”
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Comparative study of C reactive protein and serum amyloid A protein in experimental inflammation by Chambers, R E, Hutton, C W, Dieppe, P A, Whicher, J T

“…The responses of C reactive protein, measured by radial immunodiffusion and radioimmunoassay, and serum amyloid A protein, measured by radial immunodiffusion,…”
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A phase II study of interferon-alpha, interleukin-2 and 5-fluorouracil in advanced renal carcinoma: clinical data and laboratory evidence of protease activation by Joffe, J K, Banks, R E, Forbes, M A, Hallam, S, Jenkins, A, Patel, P M, Hall, G D, Velikova, G, Adams, J, Crossley, A, Johnson, P W, Whicher, J T, Selby, P J

“…To confirm the activity and evaluate the toxicity of the combination of subcutaneous interferon-alpha (IFN-alpha) and interleukin-2 (IL-2) with intravenous…”
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Strategy for determining racial and environmental similarities and differences for plasma proteins by Petersen, P H, Whicher, J T, Johnson, A M, Itoh, Y, Carlström, A B

“…The aim of this protocol is to establish a common basis for the production of reference values and well-defined and documented reference intervals for plasma…”
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Tests for detecting and monitoring the acute phase response by Stuart, J, Whicher, J T

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Acute phase response of serum amyloid A protein and C reactive protein to the common cold and influenza by Whicher, J T, Chambers, R E, Higginson, J, Nashef, L, Higgins, P G

“…C reactive protein (CRP) and serum amyloid A protein (SAA) are sensitive and rapid acute phase reactants, and their measurement for monitoring inflammatory…”
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Use of immunoglobulin heavy- and light-chain measurements compared with existing techniques as a means of typing monoclonal immunoglobulins by Whicher, J T, Wallage, M, Fifield, R

“…Using automated measurements of kappa and lambda light chains and IgG, IgA, and IgM, we assessed the utility of the kappa/lambda ratio and the heavy…”
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