Search Results - "Wheless, James W"

History of the ketogenic diet by Wheless, James W.

“…Summary Fasting and other dietary regimens have been used to treat epilepsy since at least 500 BC. To mimic the metabolism of fasting, the ketogenic diet (KD)…”
Get full text

Lateralization of epilepsy using intra‐hemispheric brain networks based on resting‐state MEG data by Pourmotabbed, Haatef, Wheless, James W., Babajani‐Feremi, Abbas

“…Focal epilepsy originates within networks in one hemisphere. However, previous studies have investigated network topologies for the entire brain. In this…”
Get full text

Identifying seizure onset zone from electrocorticographic recordings: A machine learning approach based on phase locking value by Elahian, Bahareh, Yeasin, Mohammed, Mudigoudar, Basanagoud, Wheless, James W., Babajani-Feremi, Abbas

“…•PLVs of electrodes with seizure activity are different than others prior to a seizure.•A machine learning approach can build a model for automated detection…”
Get full text

Infantile spasms: A U.S. consensus report by Pellock, John M., Hrachovy, Richard, Shinnar, Shlomo, Baram, Tallie Z., Bettis, David, Dlugos, Dennis J., Gaillard, William D., Gibson, Patricia A., Holmes, Gregory L., Nordli, Douglas R., O’Dell, Christine, Shields, W. Donald, Trevathan, Edwin, Wheless, James W.

“…Summary The diagnosis, evaluation, and management of infantile spasms (IS) continue to pose significant challenges to the treating physician. Although an…”
Get full text

Language mapping using high gamma electrocorticography, fMRI, and TMS versus electrocortical stimulation by Babajani-Feremi, Abbas, Narayana, Shalini, Rezaie, Roozbeh, Choudhri, Asim F, Fulton, Stephen P, Boop, Frederick A, Wheless, James W, Papanicolaou, Andrew C

“…Highlights • There is considerable concordance between CSM, high gamma ECoG (hgECoG), fMRI, and TMS. • TMS, hgECoG, and fMRI are valuable tools for presurgical…”
Get full text

Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology by Arzimanoglou, Alexis, MD, French, Jacqueline, MD, Blume, Warren T, MD, Cross, J Helen, MD, Ernst, Jan-Peter, MD, Feucht, Martha, MD, Genton, Pierre, MD, Guerrini, Renzo, MD, Kluger, Gerhard, MD, Pellock, John M, MD, Perucca, Emilio, MD, Wheless, James W, MD

“…Summary Lennox-Gastaut syndrome is one of the most severe epileptic encephalopathies of childhood onset. The cause of this syndrome can be symptomatic (ie,…”
Get full text

Diazepam nasal spray administration is effective to control seizure clusters irrespective of time of day by Liow, Kore, Wheless, James W, Cook, David F, Rabinowicz, Adrian L, Carrazana, Enrique

“…Neurologic circadian influences, including sleep/wake transitions, processes (e.g., hormonal variation), and behavioral patterns (e.g., consumption of food and…”
Get full text

Predicting seizure outcome of vagus nerve stimulation using MEG-based network topology by Babajani-Feremi, Abbas, Noorizadeh, Negar, Mudigoudar, Basanagoud, Wheless, James W.

“…Vagus nerve stimulation (VNS) is a low-risk surgical option for patients with drug resistant epilepsy, although it is impossible to predict which patients may…”
Get full text

SmartWatch by SmartMonitor: Assessment of Seizure Detection Efficacy for Various Seizure Types in Children, a Large Prospective Single-Center Study by Patterson, Amy L., MD, Mudigoudar, Basanagoud, MD, Fulton, Stephen, MD, McGregor, Amy, MD, Poppel, Kate Van, MD, Wheless, Margaret C, Brooks, Lai, DNP-FNP-BC, Wheless, James W., MD

“…Abstract Introduction Patients with epilepsy and their caregivers are constantly burdened with the possibility of a seizure and its consequences, such as…”
Get full text

Treatment of pediatric epilepsy: European expert opinion, 2007 by Wheless, James W, Clarke, Dave F, Arzimanoglou, Alexis, Carpenter, Daniel

“…Childhood epilepsies are a heterogeneous group of conditions that differ in diagnostic criteria and management and have dramatically different outcomes…”
Get full text

Comparison of statistical tests in effective connectivity analysis of ECoG data by Moharramipour, Ali, Mostame, Parham, Hossein-Zadeh, Gholam-Ali, Wheless, James W., Babajani-Feremi, Abbas

“…•We compared performance of three non-parametric tests in effective connectivity.•We used simulated and real electrocorticographic (ECoG) data.•Baseline…”
Get full text

On the relative merits of invasive and non-invasive pre-surgical brain mapping: New tools in ablative epilepsy surgery by Papanicolaou, Andrew C., Rezaie, Roozbeh, Narayana, Shalini, Choudhri, Asim F., Abbas-Babajani-Feremi, Boop, Frederick A., Wheless, James W.

“…•Limitations of the Wada and cortical stimulation mapping procedures.•Evidence of compatibility of invasive and non-invassive brain mapping.•The efficacy of…”
Get full text

Clinical Utility of Transcranial Magnetic Stimulation (TMS) in the Presurgical Evaluation of Motor, Speech, and Language Functions in Young Children With Refractory Epilepsy or Brain Tumor: Preliminary Evidence by Narayana, Shalini, Gibbs, Savannah K., Fulton, Stephen P., McGregor, Amy Lee, Mudigoudar, Basanagoud, Weatherspoon, Sarah E., Boop, Frederick A., Wheless, James W.

“…Accurate presurgical mapping of motor, speech, and language cortices, while crucial for neurosurgical planning and minimizing post-operative functional…”
Get full text

Pitfalls of using video‐EEG for a trial endpoint in children aged <4 years with focal seizures by Bozorg, Ali, Beller, Cynthia, Jensen, Lori, Arzimanoglou, Alexis, Chiron, Catherine, Dlugos, Dennis, Gaitanis, John, Wheless, James W., McClung, Carrie

“…Objective Double‐blind, randomized, and placebo‐controlled trial SP0967 (NCT02477839/2013‐000717‐20) did not demonstrate superior efficacy of lacosamide versus…”
Get full text

Clinical Applications of Transcranial Magnetic Stimulation in Pediatric Neurology by Narayana, Shalini, Papanicolaou, Andrew C., McGregor, Amy, Boop, Frederick A., Wheless, James W.

“…Noninvasive brain stimulation is now an accepted technique that is used as a diagnostic aid and in the treatment of neuropsychiatric disorders in adults, and…”
Get full text

Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study by Wheless, James W., Hogan, Robert Edward, Davis, Charles S., Carrazana, Enrique, Rabinowicz, Adrian L.

“…Sex differences in drug pharmacokinetics include variations in the expression of the cytochrome P450 enzymes, which are involved in the metabolism of…”
Get full text

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation by Gennarino, Vincenzo A, Alcott, Callison E, Chen, Chun-An, Chaudhury, Arindam, Gillentine, Madelyn A, Rosenfeld, Jill A, Parikh, Sumit, Wheless, James W, Roeder, Elizabeth R, Horovitz, Dafne D G, Roney, Erin K, Smith, Janice L, Cheung, Sau W, Li, Wei, Neilson, Joel R, Schaaf, Christian P, Zoghbi, Huda Y

“…The brain is sensitive to the dose of MeCP2 such that small fluctuations in protein quantity lead to neuropsychiatric disease. Despite the importance of MeCP2…”
Get full text

Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies by Becker, Danielle A., Wheless, James W., Sirven, Joseph, Tatum, William O., Rabinowicz, Adrian L., Carrazana, Enrique

“…Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may experience…”
Get full text

Genotype/phenotype correlation in 325 individuals referred for a diagnosis of tuberous sclerosis complex in the United States by Au, Kit Sing, Williams, Aimee T, Roach, E Steve, Batchelor, Lori, Sparagana, Steven P, Delgado, Mauricio R, Wheless, James W, Baumgartner, James E, Roa, Benjamin B, Wilson, Carolyn M, Smith-Knuppel, Teresa K, Cheung, Min-Yuen C, Whittemore, Vicky H, King, Terri M, Northrup, Hope

“…Tuberous sclerosis complex is an autosomal dominant neurocutaneous disorder marked by hamartoma growth in multiple organ systems. We performed mutational…”
Get full text

Treatment of Refractory Convulsive Status Epilepticus in Children: Other Therapies by Wheless, James W., MD

“…Refractory convulsive status epilepticus occurs when seizures are not controlled with initial benzodiazepine therapy or a subsequent anticonvulsant drug…”
Get full text