Search Results - "Wheelock, Michael"
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1
Autoinhibition and Polo-Dependent Multisite Phosphorylation Restrict Activity of the Histone H3 Kinase Haspin to Mitosis
Published in Molecular cell (12-12-2013)“…The mitosis-specific phosphorylation of histone H3 at Thr3 (H3T3ph) plays an important role in chromosome segregation by recruiting Aurora B. H3T3…”
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Journal Article -
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The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis
Published in Nature reviews. Molecular cell biology (01-12-2012)“…Key Points The chromosomal passenger complex (CPC) is a 'master controller' of cell division that is formed by a kinase module (Aurora B kinase) and a…”
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Journal Article -
3
Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression
Published in The Journal of cell biology (03-04-2017)“…The chromosomal passenger complex (CPC), composed of inner centromere protein (INCENP), Survivin, Borealin, and the kinase Aurora B, contributes to the…”
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Journal Article -
4
Methionine‐deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF‐I and insulin levels, and increases hepatocyte MIF levels and stress resistance
Published in Aging cell (01-06-2005)“…Summary A diet deficient in the amino acid methionine has previously been shown to extend lifespan in several stocks of inbred rats. We report here that a…”
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Journal Article -
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Using Proactive Risk Assessment (HFMEA) to Improve Patient Safety and Quality Associated with Intraocular Lens Selection and Implantation in Cataract Surgery
Published in Joint Commission journal on quality and patient safety (01-10-2019)“…A proactive risk assessment using the Healthcare Failure Mode and Effect Analysis (HFMEA) process was completed on the intraocular lens (IOL) selection and…”
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6
Evaluation of Clinical Measures of Equilibrium
Published in The Laryngoscope (01-03-1998)“…Objective: Evaluate the clinical utility of several simple measures of static and dynamic equilibrium in human subjects. In particular, one proposed clinical…”
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Journal Article Conference Proceeding -
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Bilateral vestibular paresis: diagnosis and treatment
Published in Otolaryngology-head and neck surgery (01-01-1991)“…Patients with bilateral peripheral vestibular dysfunction present a substantial diagnostic and therapeutic challenge to the otologist. Caloric irrigations that…”
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Habituation therapy for chronic vestibular dysfunction: preliminary results
Published in Otolaryngology-head and neck surgery (01-07-1990)“…Chronic vestibular dysfunction is often a frustrating problem for both patient and physician. A program of customized vestibular habituation therapy is…”
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Journal Article -
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Vestibular and balance rehabilitation therapy
Published in Annals of otology, rhinology & laryngology (01-03-1993)“…A prospective observational study of the performance of patients enrolled in an individually customized program of habituation and balance rehabilitation…”
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10
Hormone-Treated Snell Dwarf Mice Regain Fertility But Remain Long Lived and Disease Resistant
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-12-2004)“…Snell dwarf mice have multiple hormonal deficits, but the way in which these deficits postpone aging are still uncertain. In this study, Snell dwarf mice…”
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Journal Article -
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Association of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in a Large Cohort from a Single Center
Published in Investigative ophthalmology & visual science (01-05-2004)“…To examine the effect of apolipoprotein E (APOE) alleles on age-related macular degeneration (AMD) risk and on age at diagnosis of AMD in a large patient…”
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Journal Article -
12
Factors Influencing the Adoption of Cloud Storage by Information Technology Decision Makers
Published 2013“…This dissertation uses a survey methodology to determine the factors behind the decision to adopt cloud storage. The dependent variable in the study is the…”
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Dissertation -
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Quantitative Trait Locus Mapping for Age-Related Cataract Severity and Synechia Prevalence Using Four-Way Cross Mice
Published in Investigative ophthalmology & visual science (01-06-2004)“…The goal of this study was to map mouse quantitative trait loci (QTL) that influence the development of murine age-related cataract and synechia, by using a…”
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Journal Article -
14
Hyperglycemia, impaired glucose tolerance and elevated glycated hemoglobin levels in a long-lived mouse stock
Published in Experimental gerontology (01-04-2005)“…We have previously demonstrated that two wild-derived stocks of mice, Idaho and Majuro, are significantly longer-lived than mice of a control stock (DC)…”
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Journal Article -
15
Free scapular osteocutaneous flap for mandibular reconstruction
Published in Archives of otolaryngology--head & neck surgery (01-11-1989)“…Seventeen patients, 4 of whom had osteoradionecrosis, underwent mandibular reconstruction with a revascularized scapular osteocutaneous flap. The mean length…”
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Factors influencing the adoption of cloud storage by information technology decision makers
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Dissertation -
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The free scapular flap for head and neck reconstruction
Published in American journal of otolaryngology (01-09-1990)“…The free scapular flap is a versatile flap for soft tissue and bony reconstruction of the head and neck. It has a very reliable blood supply and is easy to…”
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Journal Article -
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Race, Reason, and the State: Enlightenment Ideology and Black Critique
Published 01-01-2001“…The burden of transatlantic black literary studies is to situate early black writing within the larger history and discourse of eighteenth-century Western…”
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Dissertation -
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Experimental Manipulation of the Spheno-occipital Synchondrosis and Its Effects on Craniofacial Growth of the Growing Rabbit
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Dissertation