Search Results - "Wheelock, C E"

Gene expression signatures, pathways and networks in carotid atherosclerosis by Perisic, L., Aldi, S., Sun, Y., Folkersen, L., Razuvaev, A., Roy, J., Lengquist, M., Åkesson, S., Wheelock, C. E., Maegdefessel, L., Gabrielsen, A., Odeberg, J., Hansson, G. K., Paulsson‐Berne, G., Hedin, U.

“…Background Embolism from unstable atheromas in the carotid bifurcation is a major cause of stroke. Here, we analysed gene expression in endarterectomies from…”
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Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose‐lowering therapy by Mahdi, A., Kövamees, O., Checa, A., Wheelock, C. E., Heijne, M., Alvarsson, M., Pernow, J.

“…Background Arginase is implicated in the pathogenesis behind endothelial dysfunction in type 2 diabetes mellitus (T2DM) by its inhibition of nitric oxide…”
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Cannabinoid receptor 2 augments eosinophil responsiveness and aggravates allergen‐induced pulmonary inflammation in mice by Frei, R. B., Luschnig, P., Parzmair, G. P., Peinhaupt, M., Schranz, S., Fauland, A., Wheelock, C. E., Heinemann, A., Sturm, E. M.

“…Background Accumulation of activated eosinophils in tissue is a hallmark of allergic inflammation. The endocannabinoid 2‐arachidonoylglycerol (2‐AG) has been…”
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Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematosus: a cross-sectional study by Checa, A, Idborg, H, Zandian, A, Sar, D Garcia, Surowiec, I, Trygg, J, Svenungsson, E, Jakobsson, P-J, Nilsson, P, Gunnarsson, I, Wheelock, C E

“…Objective The objective of this study was to investigate the association of clinical and renal disease activity with circulating sphingolipids in patients with…”
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Inhibition, recovery and oxime-induced reactivation of muscle esterases following chlorpyrifos exposure in the earthworm Lumbricus terrestris by Collange, B., Wheelock, C.E., Rault, M., Mazzia, C., Capowiez, Y., Sanchez-Hernandez, J.C.

“…Assessment of wildlife exposure to organophosphorus (OP) pesticides generally involves the measurement of cholinesterase (ChE) inhibition, and complementary…”
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Substituted 3-phenylpropenoates and related analogs: electron ionization mass spectral fragmentation and density functional theory calculations by Wheelock, C.E, Colvin, M.E, Sanborn, J.R, Hammock, B.D

“…Analysis of ethyl 3-(2-chlorophenyl)propenoate by electron ionization mass spectrometry showed the distinct loss of an ortho chlorine. To characterize the…”
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Synthesis of New Carboxylesterase Inhibitors and Evaluation of Potency and Water Solubility by Wheelock, Craig E, Severson, Tonya F, Hammock, Bruce D

“…Carboxylesterases are essential enzymes in the hydrolysis and detoxification of numerous pharmaceuticals and pesticides. They are vital in mediating…”
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Effect of nutritional state on Hsp60 levels in the rotifer Brachionus plicatilis following toxicant exposure by Wheelock, C.E, Baumgartner, T.A, Newman, J.W, Wolfe, M.F, Tjeerdema, R.S

“…The nutritional state of an organism can affect the results of toxicity testing. Here we exemplified this fact by examining the effect of nutritional…”
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Implementing precision medicine in a regionally organized healthcare system in Sweden by Fioretos, Thoas, Wirta, Valtteri, Cavelier, Lucia, Berglund, Eva, Friedman, Mikaela, Akhras, Michael, Botling, Johan, Ehrencrona, Hans, Engstrand, Lars, Helenius, Gisela, Fagerqvist, Therese, Gisselsson, David, Gruvberger-Saal, Sofia, Gyllensten, Ulf, Heidenblad, Markus, Höglund, Kina, Jacobsson, Bo, Johansson, Maria, Johansson, Åsa, Soller, Maria Johansson, Landström, Maréne, Larsson, Pär, Levin, Lars-Åke, Lindstrand, Anna, Lovmar, Lovisa, Lyander, Anna, Melin, Malin, Nordgren, Ann, Nordmark, Gunnel, Mölling, Paula, Palmqvist, Lars, Palmqvist, Richard, Repsilber, Dirk, Sikora, Per, Stenmark, Bianca, Söderkvist, Peter, Stranneheim, Henrik, Strid, Tobias, Wheelock, Craig E., Wadelius, Mia, Wedell, Anna, Edsjö, Anders, Rosenquist, Richard

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Evaluation of Fish Models of Soluble Epoxide Hydrolase Inhibition by Newman, John W., Denton, Debra L., Morisseau, Christophe, Koger, Cory S., Wheelock, Craig E., Hinton, David E., Hammock, Bruce D.

“…Substituted ureas and carbamates are mechanistic inhibitors of the soluble epoxide hydrolase (sEH). We screened a set of chemicals containing these…”
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Chronic Airway Diseases Early Stratification (CADSET): a new ERS Clinical Research Collaboration by Agusti, Alvar, Faner, Rosa, Donaldson, Gavin, Heuvelin, Elise, Breyer-Kohansal, Robab, Melén, Erik, Maitland-van der Zee, Anke H, Vestbo, Jørgen, Allinson, James P, Vanfleteren, Lowie E G W, van den Berge, Maarten, Adcock, Ian M, Lahousse, Lies, Brusselle, Guy, Wedzicha, Jadwiga A

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Hsp60-induced tolerance in the rotifer Brachionus plicatilis exposed to multiple environmental contaminants by WHEELOCK, C. E, WOLFE, M. F, OLSEN, H, TJEERDEMA, R. S, SOWBY, M. L

“…Hsp60 induction was selected as a sublethal endpoint of toxicity for Brachionus plicatilis exposed to a water accommodated fraction (WAF) of Prudhoe Bay crude…”
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Inhibition of 2‐arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U‐46619 by Hillard, C J, Ho, W‐Sv, Thompson, J, Gauthier, K M, Wheelock, C E, Huang, H, Hammock, B D

“…Background and purpose: Cerebrovascular smooth muscle cells express the CB1 cannabinoid receptor and CB1 agonists produce vasodilatation of the middle cerebral…”
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3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues by NAKAGAWA, Yoshiaki, WHEELOCK, Craig E, MORISSEAU, Christophe, GOODROW, Marvin H, HAMMOCK, Bruce G, HAMMOCK, Bruce D

“…Two hundred and seventy-one compounds including benzoylureas, arylureas and related compounds were assayed using recombinant murine soluble epoxide hydrolase…”
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Characterization of Hsp60 response in the rotifer, Brachionus plicatilis, exposed to multiple environmental contaminants by Wheelock, C.E., Wolfe, M.F., Olsen, H., Tjeerdema, R.S.

“…Many bioassays examine the effects of a single Stressor on organism health, but in the environment organisms are rarely, if ever, exposed to a single Stressor…”
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From Genome to Proteome: Integration and proteome completion - 8th Siena Meeting by Wheelock, Asa M, Wheelock, Craig E

“…The Siena Meeting is designed to cover the breadth of proteomics-based research, with a particular focus on clinical applications as well as emerging…”
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C21 APPLYING 'OMICS TECHNOLOGIES TO REVEAL GENE REGULATORS AND BIOMARKERS IN LUNG DEVELOPMENT AND DISEASE: Non-Invasive Sub-Phenotyping Of Asthma In The U-Biopred Study By Analysis Of Urinary Lipid Mediator Excretion Patterns by Wheelock, C E, Kolmert, J, Lefaudeux, D, Sjodin, M, Balgoma, D, Sousa, A R, Corfield, J, Pandis, I, Djukanovic, R, Dahlen, S-E

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The octadecanoids: an emerging class of lipid mediators by Quaranta, Alessandro, Revol-Cavalier, Johanna, Wheelock, Craig E

“…Oxylipins are enzymatic and non-enzymatic metabolites of mono- or polyunsaturated fatty acids that encompass potent lipid mediators including the eicosanoids…”
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The role of gene-environment interactions in lung disease: the urgent need for the exposome by Wheelock, Craig E, Rappaport, Stephen M

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Abnormal n-6 fatty acid metabolism in cystic fibrosis contributes to pulmonary symptoms by Wheelock, Craig E., Strandvik, Birgitta

“…•· Severe CF phenotype exhibit linoleic acid deficiency, which is associated with poor growth.•Linoleic acid positively influences pulmonary…”
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