Search Results - "Wheeler, T N"
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The inotropic and beta blocking effects of a chimeric molecule that putatively inhibits both type III phosphodiesterase and beta adrenoceptors in anesthetized dogs
Published in The Journal of pharmacology and experimental therapeutics (01-06-1993)“…The hemodynamic and beta adrenergic blocking effects of GI104313, a chimeric molecule containing a phosphodiesterase-inhibiting pyradazinone and a beta…”
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Substrate Specificity in Short-Chain Phospholipid Analogs at the Active Site of Human Synovial Phospholipase A2
Published in Journal of medicinal chemistry (01-11-1994)“…The substrate specificity at the active site of recombinant human synovial fluid phospholipase A2 (hs-PLA2) was investigated by the preparation of a series of…”
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3
Discovery of bioavailable inhibitors of secretory phospholipase A2
Published in Pharmaceutical biotechnology (1998)“…Substrate-mimetic inhibitors of sPLA2 with submicromolar in vitro potency were discovered by use of a novel dual substrate screening strategy. In vivo…”
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4
Charles Christopher Nicholson Roberts
Published in BMJ (Online) (27-01-2014)“…[...]Chris was not only a GP; he was for many years involved in industrial medicine with a major nickel alloy factory in Hereford, provided occupational…”
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5
Synthesis of 1-aminocyclopropenecarboxylic acid: the unsaturated analog of ACC
Published in Journal of organic chemistry (01-10-1987)Get full text
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Synthesis of 4-alkenoic and 4-alkynoic esters via alkylation of O-silylated ketene acetals
Published in Journal of organic chemistry (01-02-1984)Get full text
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Synthesis and biological activity of pyrethroids derived from halo-4-alkenoic acids
Published in Journal of agricultural and food chemistry (01-01-1984)Get full text
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6-Azasteroids: structure-activity relationships for inhibition of type 1 and 2 human 5 alpha-reductase and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase
Published in Journal of medicinal chemistry (22-07-1994)“…6-Azaandrost-4-en-3-ones were synthesized and tested versus human type 1 and 2 steroid 5 alpha-reductase (5AR) and human adrenal 3 beta-hydroxy-delta 5-steroid…”
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9
Synthesis and biological activity of pyrethroids derived from halo-4-alkenoic acids
Published in Journal of agricultural and food chemistry (01-01-1984)“…Sixty-two examples of pyrethroids derived from halo-4-alkenoic acids have been synthesized. The halo-4-alkenoic acids were prepared by a modified malonic ester…”
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D-nor steroids. 3. Synthesis of conformationally defined cyclobutylamines and alcohols
Published in Journal of the American Chemical Society (25-02-1970)Get full text
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D-Nor steroids. IV. Carbonium ion rearrangements of conformationally defined cyclobutanes
Published in Journal of the American Chemical Society (01-02-1970)Get full text
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Synthesis and insecticidal activities of pyrethroids derived from 3-methyl-2-(3',4'-dihydronaphthyl)butanoic acids
Published in Journal of agricultural and food chemistry (01-09-1984)Get full text
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Conversion of black and white prints to color in daylight. A demonstration lecture for general and organic courses
Published in Journal of chemical education (01-09-1975)“…A black and white print is converted to a full color print with the lights on; includes a detailed discussion of the chemical processes involved in the…”
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Synthesis of spiro[4.6]undecane-1,6-dione
Published in Journal of organic chemistry (01-05-1974)Get full text
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