Search Results - "Wheeler, Jun X."

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  1. 1

    Quantitation of thrombin-activatable fibrinolysis inhibitor in human plasma by isotope dilution mass spectrometry by Wheeler, Jun X., Thelwell, Craig, Rigsby, Peter, Whiting, Gail

    Published in Analytical biochemistry (01-02-2022)
    “…Measurement of Thrombin-activatable fibrinolysis inhibitor (TAFI) in human plasma is dependent on reproducible assays. To date, standards for measuring TAFI…”
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    Measurement of surface protein antigens, PorA and PorB, in Bexsero vaccine using quantitative mass spectrometry by Whiting, Gail, Vipond, Caroline, Facchetti, Alessandra, Chan, Hannah, Wheeler, Jun X.

    Published in Vaccine (05-02-2020)
    “…Bexsero is a multivalent vaccine containing outer membrane vesicles (OMV) derived from Neisseria meningitidis group B strain NZ98/254 and three recombinant…”
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    A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge by Chan, Win-Yan, Entwisle, Claire, Ercoli, Giuseppe, Ramos-Sevillano, Elise, McIlgorm, Ann, Cecchini, Paola, Bailey, Christopher, Lam, Oliver, Whiting, Gail, Green, Nicola, Goldblatt, David, Wheeler, Jun X, Brown, Jeremy S

    Published in Infection and immunity (01-03-2019)
    “…Current vaccination against uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We…”
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    Quantification of Müllerian Inhibiting Substance/Anti-Müllerian Hormone polypeptide by isotope dilution mass spectrometry by Whiting, Gail, Ferguson, Jackie, Fang, Min, Pepin, David, Donahoe, Patricia, Matejtschuk, Paul, Burns, Chris, Wheeler, Jun X.

    Published in Analytical biochemistry (01-11-2018)
    “…Measurement of serum concentrations of Müllerian inhibiting substance (MIS), also known as anti-Müllerian Hormone (AMH) by immunoassay is gaining clinical…”
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    The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies by Gurjar, Shalom A., Wheeler, Jun X., Wadhwa, Meenu, Thorpe, Robin, Kimber, Ian, Derrick, Jeremy P., Dearman, Rebecca J., Metcalfe, Clive

    Published in The Journal of biological chemistry (20-12-2019)
    “…Therapeutic mAbs are used to manage a wide range of cancers and autoimmune disorders. However, mAb-based treatments are not always successful, highlighting the…”
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    Proteomic Analysis Reveals Temporal Changes in Protein Expression in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes In Vitro by Hellen, Nicola, Pinto Ricardo, Carolina, Vauchez, Karine, Whiting, Gail, Wheeler, Jun X, Harding, Sian E

    Published in Stem cells and development (01-05-2019)
    “…Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold great promise for regenerative medicine and in vitro screening. Despite displaying…”
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    Mass spectrometry analysis reveals differences in the host cell protein species found in pseudotyped lentiviral vectors by Johnson, Sabine, Wheeler, Jun X., Thorpe, Robin, Collins, Mary, Takeuchi, Yasuhiro, Zhao, Yuan

    Published in Biologicals (01-03-2018)
    “…Lentiviral vectors (LVs) have been successfully used in clinical trials showing long term therapeutic benefits. Studying the role of cellular proteins in…”
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    Dissection of the function of the RmpM periplasmic protein from Neisseria meningitidis by Maharjan, Sunil, Saleem, Muhammad, Feavers, Ian M, Wheeler, Jun X, Care, Rory, Derrick, Jeremy P

    “…RmpM is a periplasmic protein from Neisseria meningitidis that comprises an N-terminal domain (residues 1-47) and a separate globular C-terminal domain…”
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    Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis by Awanye, Amaka M., Chang, Chun-Mien, Wheeler, Jun X., Chan, Hannah, Marsay, Leanne, Dold, Christina, Rollier, Christine S., Bird, Louise E., Nettleship, Joanne E., Owens, Raymond J., Pollard, Andrew J., Derrick, Jeremy P.

    Published in Scientific reports (02-05-2019)
    “…Outer membrane vesicle (OMV)- based vaccines have been used to provide strain-specific protection against capsular group B Neisseria meningitidis infections,…”
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    In vitro and in vivo growth alter the population dynamic and properties of a Jeryl Lynn mumps vaccine by Connaughton, Sarah M, Wheeler, Jun X, Vitková, Eva, Minor, Philip, Schepelmann, Silke

    Published in Vaccine (26-08-2015)
    “…Highlights • Mumps vaccines contain live attenuated viruses that are manufactured in cell substrates. • The production of the JL-CK vaccine in primary canine…”
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    Characterisation of the Protein Content of a Meningococcal Outer Membrane Vesicle Vaccine by Polyacrylamide Gel Electrophoresis and Mass Spectrometry by Vipond, Caroline, Wheeler, Jun X., Jones, Christopher, Feavers, Ian M., Suker, Janet

    Published in Human vaccines (01-03-2005)
    “…The development and evaluation of outer membrane vesicles as vaccines against meningococcal disease has been carried out for more than two decades. Although…”
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    Identification of vaccine antigens using integrated proteomic analyses of surface immunogens from serogroup B Neisseria meningitidis by Tsolakos, Nikos, Brookes, Charlotte, Taylor, Stephen, Gorringe, Andrew, Tang, Christoph M., Feavers, Ian M., Wheeler, Jun X.

    Published in Journal of proteomics (14-04-2014)
    “…Meningococcal surface proteins capable of evoking a protective immune response are candidates for inclusion in protein-based vaccines against serogroup B…”
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    Quantitation of haemagglutinin in H5N1 influenza viruses reveals low haemagglutinin content of vaccine virus NIBRG-14 (H5N1) by Harvey, Ruth, Wheeler, Jun X, Wallis, Chantal L, Robertson, James S, Engelhardt, Othmar G

    Published in Vaccine (02-12-2008)
    “…Abstract The assessment of potential candidate influenza vaccine viruses includes a number of factors. Growth properties of the virus and yield of antigen,…”
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    Proteomic analysis of a meningococcal outer membrane vesicle vaccine prepared from the group B strain NZ98/254 by Vipond, Caroline, Suker, Janet, Jones, Christopher, Tang, Christoph, Feavers, Ian M., Wheeler, Jun X.

    Published in Proteomics (Weinheim) (01-06-2006)
    “…In the absence of a suitable carbohydrate‐based vaccine, outer membrane vesicle (OMV) vaccines have been used to disrupt outbreaks of serogroup B meningococcal…”
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    Identification of peptide sequences as a measure of Anthrax vaccine stability during storage by Whiting, Gail, Wheeler, Jun X, Rijpkema, Sjoerd

    “…The UK anthrax vaccine is an alum precipitate of a sterile filtrate of Bacillus anthracis Sterne culture (AVP). An increase in shelf life of AVP from 3 to 5…”
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    Bioanalysis of meningococcal vaccines by Ravenscroft, Neil, Wheeler, Jun X, Jones, Christopher

    Published in Bioanalysis (01-02-2010)
    “…Meningococcal meningitis is feared because of the rapid onset of severe disease from mild symptoms and, therefore, is an important target for vaccine research…”
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