Search Results - "Wheeler, Graycen E."
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Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling
Published in Molecular biology of the cell (15-02-2021)“…Sustained cell migration is essential for wound healing and cancer metastasis. The epidermal growth factor receptor (EGFR) signaling cascade is known to drive…”
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Journal Article -
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Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers
Published in Nucleic acids research (28-02-2018)“…Abstract Histone deacetylase inhibitors (HDACIs) are known to alter gene expression by both up- and down-regulation of protein-coding genes in normal and…”
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Journal Article -
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Protocol for Analysis and Consolidation of TrackMate Outputs for Measuring Two-Dimensional Cell Motility using Nuclear Tracking
Published in Journal of visualized experiments (18-12-2021)“…Collective cellular migration plays a key role in many fundamental biological processes including development, wound healing, and cancer metastasis. To…”
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Journal Article -
4
Learning anisotropic interaction rules from individual trajectories in a heterogeneous cellular population
Published in Journal of the Royal Society interface (12-10-2022)“…Interacting particle system (IPS) models have proven to be highly successful for describing the spatial movement of organisms. However, it is challenging to…”
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Journal Article -
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Explorations of the Cell Signaling Behind Keratinocyte Motility, Cancer Drug Resistance, Adipocyte Differentiation, and Other Cellular Processes
Published 01-01-2021“…The regulation of cellular motility and proliferation in epithelial tissues is crucial for wound healing and maintenance of the epithelial sheet, but…”
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Dissertation -
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Learning Anisotropic Interaction Rules from Individual Trajectories in a Heterogeneous Cellular Population
Published 29-04-2022“…Interacting particle system (IPS) models have proven to be highly successful for describing the spatial movement of organisms. However, it has proven…”
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Journal Article