Search Results - "Wheeler, B."
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1
Gradient light interference microscopy for 3D imaging of unlabeled specimens
Published in Nature communications (08-08-2017)“…Multiple scattering limits the contrast in optical imaging of thick specimens. Here, we present gradient light interference microscopy (GLIM) to extract…”
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2
Amino acid and lipid metabolism in post-gestational diabetes and progression to type 2 diabetes: A metabolic profiling study
Published in PLoS medicine (20-05-2020)“…Women with a history of gestational diabetes mellitus (GDM) have a 7-fold higher risk of developing type 2 diabetes (T2D) during midlife and an elevated risk…”
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3
Environmental, health, wellbeing, social and equity effects of urban green space interventions: A meta-narrative evidence synthesis
Published in Environment international (01-09-2019)“…As populations become increasingly urbanised, the preservation of urban green space (UGS) becomes paramount. UGS is not just dedicated recreational space such…”
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4
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Published in Lab on a chip (05-05-2020)“…Rapid, sensitive and specific detection and reporting of infectious pathogens is important for patient management and epidemic surveillance. We demonstrated a…”
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5
Identification of an oncogenic RAB protein
Published in Science (American Association for the Advancement of Science) (09-10-2015)“…In a short hairpin RNA screen for genes that affect AKT phosphorylation, we identified the RAB35 small guanosine triphosphatase (GTPase)–a protein previously…”
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6
Knowledge, experiences, and perceptions of medications for opioid use disorder among Black Kentuckians
Published in Annals of medicine (Helsinki) (01-12-2024)“…Opioid overdoses have continued to increase at higher rates among Black Americans compared to people from other racial groups. Despite demonstrated…”
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A Predictive Metabolic Signature for the Transition From Gestational Diabetes Mellitus to Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-09-2016)“…Gestational diabetes mellitus (GDM) affects 3-14% of pregnancies, with 20-50% of these women progressing to type 2 diabetes (T2D) within 5 years. This study…”
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A systematic review of clinic and community intervention to increase fecal testing for colorectal cancer in rural and low-income populations in the United States - How, what and when?
Published in BMC cancer (06-01-2018)“…Interventions to improve fecal testing for colorectal cancer (CRC) exist, but are not yet routine practice. We conducted this systematic review to determine…”
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Transcription Adaptation during In Vitro Adipogenesis and Osteogenesis of Porcine Mesenchymal Stem Cells: Dynamics of Pathways, Biological Processes, Up-Stream Regulators, and Gene Networks
Published in PloS one (23-09-2015)“…The importance of mesenchymal stem cells (MSC) for bone regeneration is growing. Among MSC the bone marrow-derived stem cells (BMSC) are considered the gold…”
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Preoperatively Misclassified, Surgically Removed Benign Renal Masses: A Systematic Review of Surgical Series and United States Population Level Burden Estimate
Published in The Journal of urology (2015)“…Purpose A significant proportion of renal masses removed for suspected malignancy are histologically benign with the probability inversely proportional…”
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CellProfiler Analyst: data exploration and analysis software for complex image-based screens
Published in BMC bioinformatics (15-11-2008)“…Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. Here, we describe…”
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Adiponectin-induced ERK and Akt Phosphorylation Protects against Pancreatic Beta Cell Apoptosis and Increases Insulin Gene Expression and Secretion
Published in The Journal of biological chemistry (29-10-2010)“…The functional impact of adiponectin on pancreatic beta cells is so far poorly understood. Although adiponectin receptors (AdipoR1/2) were identified, their…”
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Recreational physical activity in natural environments and implications for health: A population based cross-sectional study in England
Published in Preventive medicine (01-10-2016)“…Abstract Background Building on evidence that natural environments (e.g. parks, woodlands, beaches) are key locations for physical activity, we estimated the…”
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14
Declining liver utilization for transplantation in the United States and the impact of donation after cardiac death
Published in Liver transplantation (01-01-2013)“…Worsening donor liver quality resulting in decreased organ utilization may be contributing to the recent decline in liver transplants nationally. We sought to…”
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15
Epidemiology of Esophageal Cancer
Published in The Surgical clinics of North America (01-10-2012)“…This article discusses the incidence, geographic differences, and risk factors for the 2 most common cancers of the esophagus: squamous cell and adenocarcinoma…”
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Cancer Incidence Among US Medicare ESRD Patients Receiving Hemodialysis, 1996-2009
Published in American journal of kidney diseases (01-05-2015)“…Background Patients with end-stage renal disease (ESRD) receiving dialysis have been reported to have increased risk of cancer. However, contemporary cancer…”
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Novel ecosystems in the Anthropocene: a revision of the novel ecosystem concept for pragmatic applications
Published in Ecology and society (01-01-2014)“…Ecologists have developed terminology to distinguish ecosystems based on the degree of human alteration. To this end, ecosystems can be characterized as “novel…”
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Clinical review: insulin pump-associated adverse events in adults and children
Published in Acta diabetologica (01-12-2015)“…Aims Insulin pumps are a vital and rapidly developing tool in the treatment of type 1 diabetes mellitus in both adults and children. Many studies have…”
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Multi-level predictors of being up-to-date with colorectal cancer screening
Published in Cancer causes & control (01-12-2023)“…Purpose Assessing factors associated with being up-to-date with colorectal cancer (CRC) screening is important for identifying populations for which targeted…”
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Molecular and Metabolic Evidence for Mitochondrial Defects Associated With β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-02-2010)“…Molecular and Metabolic Evidence for Mitochondrial Defects Associated With β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes Hongfang Lu , Vasilij Koshkin…”
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